If you have leukemia or lymphoma, you may need a stem cell transplant. These cells help replace cells damaged by the cancer. They also let your body recover faster from intense chemotherapy and radiation treatments.
For some, it may be the best -- or only -- approach.
They grow inside your marrow, the soft tissue of your bones. Theyre also in your blood, as well as blood from umbilical cords.
As they mature, blood stem cells change into threetypes of cells your body needs:
There are two types of transplants. Your doctor will decide which is best for you.
In an autologous (AUTO) transplant, doctors take healthy stem cells from your bone marrow or blood. Theyre frozen and carefully stored. Since they're outside your body, they arent harmed during the chemotherapy or radiation treatments youll need to get rid of your cancer cells.
After your treatment ends, your thawed stem cells are returned to your bloodstream through an IV. Theyll find their way back to your bone marrow.
Once there, they can help your body make healthy blood cells again.
In an allogeneic (ALLO)transplant, you get healthy stem cells from a donor.
Its important that the donors bone marrow closely matches yours. If it doesnt, your body may reject their cells. Your donor might be a family member. You can also get stem cells from someone you dont know.
Before an ALLO transplant, youll get chemotherapy, radiation, or both. This wipes out your own stem cells and gets your body ready for the new ones soon after your treatment is done.
If your doctor cant find a donor,theymay use cells from donated umbilical cord blood. After a baby is born, blood rich in stem cells remains in the discarded cord and placenta. It can be frozen and stored in a cord blood bankuntil its stem cells are needed.
Cord blood is tested before its banked. This lets doctors quickly check to see if theres a match for you. Plus, the pairing doesnt have to be as perfect as it would be from a donor.
If youre being treated with your own stem cells, you may have high-dose chemotherapy first. This can cause side effects. What and how severe they are depend on the dose. You might have:
That doesnt sound great, but advances in cancer treatment can make them easier to live with.
When you get stem cells from a donor or cord blood, theres a risk of something called graft-versus.-host disease. Its when your body fights to get rid of the new cells, or the cells launch an attack against you. It could happen right after the transplant or not until a year later.
Thanks to strides in the matching process in the past decade or so, your odds of having more problems from the treatment are much lower than they used to be.Youll also get medicine after your transplant that can workto keep those problems at bay.
Still, if youre older, it can be harder for you to manage side effects. Also, its more likely youhave another health condition like high blood pressure or diabetes. Your doctor may want you to have a reduced-intensity, or mini, stem cell transplant.
Youll start out with a lower dose of chemo and radiation before you get the stem cells. Its less taxing on your body, and new cells can still grow and fight your cancer.
They sound like special cells that fight cancer. They arent. Theyre cells that advance cancer.
Experts used to think all cancer cells were the same. Now, theres reason to believe that special, fast-growing cancer stem cells keep your disease alive by reproducing.
If thats true, in the next few years, the focus of treatments could shift from trying to shrink tumors to trying to kill this type of cell.
WebMD Medical Reference Reviewed by Kumar Shital, DO on July 17, 2020
MD Anderson Cancer Center: Stem Cell Transplantation.
National Cancer Institute: Stem Cell Transplant.
Linda Burns, MD, vice president and medical director of health services research, National Marrow Donor Program/Be The Match, Minneapolis, MN.
Jack Jacoub, MD, medical oncologist and director of thoracic oncology at MemorialCare Cancer Institute at Orange Coast Memorial Medical Center, Fountain Valley, CA.
American Society of Clinical Oncology: What Is a Stem Cell Transplant?
American Cancer Society: Stem Cell Transplant for Multiple Myeloma.
City of Hope: Breakthroughs: Mini Stem Cell Transplant: What Is It and How Does It Treat Cancer?
National Cord Blood Program: Cord Blood Q&A.
Stanford Medicine Ludwig Center for Cancer Stem Cell Research and Medicine: The Stem Cell Theory of Cancer.
Cleveland Clinic: Graft vs Host Disease: An Overview in Bone Marrow Transplant.
Read this article:
Stem Cell Transplants: A Lifesaving Treatment for Cancer ...
- Sophomore saves sister's life with stem cell donation - University of Miami - August 5th, 2021
- Myelodysplastic Syndrome Treatment Options - Healthline - August 5th, 2021
- Gold River Productions, Inc. (GRPS) Appoints Michael Berkowitz to spearhead the Rejuvenation Division with StemSpa - Yahoo Finance - August 5th, 2021
- Colin Jackson health: Im in constant pain Athlete to undergo stem cell therapy to help - Express - August 5th, 2021
- The Basics of MDS: Diagnosis and Staging - Curetoday.com - August 5th, 2021
- Blood donation clinic will honour life of Jocelyn McGlynn - Chatham Daily News - August 5th, 2021
- Pharming Group reports financial results for the first half of 2021 - PRNewswire - August 5th, 2021
- Symptoms of seizures: Early signs, post-seizure, and more - Medical News Today - August 5th, 2021
- Lymph nodes: Purpose, location, and disease warning signs - Medical News Today - June 8th, 2021
- Teesside baby will be third in country to have ground breaking complex cancer treatment - Teesside Live - June 8th, 2021
- Brave Nathaniel Nabena, 9, all smiles as he has life-saving procedure - thanks to you - The Mirror - June 8th, 2021
- Local veterinary clinics offer integrated care options for pets - williamsonherald.com - June 8th, 2021
- Blood cancer and leukaemia: UAE oncologist urges public to spot the symptoms - The National - June 8th, 2021
- Replotting the human: the thorny ethics of growing babies outside the womb - Prospect - June 8th, 2021
- Crossroads of life: Jordan Reed's journey through concussions, injuries and post-NFL healing - The Athletic - June 8th, 2021
- B-cell acute lymphoblastic leukemia: What to know - Medical News Today - May 28th, 2021
- Chronic lymphocytic leukemia and stomach pain: What is the link? - Medical News Today - May 28th, 2021
- Top 12 Disruptive Gene and Cell Therapy Technologies Announced - GlobeNewswire - May 28th, 2021
- BlueRock and Senti Collaborate to Build Smarter, Disease-Fighting Cell Therapies - BioSpace - May 28th, 2021
- Living with blood cancer - Lara Said - Times of Malta - May 28th, 2021
- 3D Printed Stem Cells Could Revolutionize Neuroscience, Aid Treatment and Understanding of Neural Diseases - Science Times - May 28th, 2021
- In the War on Cancer, Science Is Winning - The Wall Street Journal - May 28th, 2021
- Whats Causing Black Fungus? Here Is What The Doctors Have To Say - The Logical Indian - May 28th, 2021
- University of Pittsburgh Won't Explain its Planned Parenthood Ties | Opinion - Newsweek - May 28th, 2021
- Trial treatment with a mythologically-inspired name saves life of young man diagnosed with multiple myeloma - Neos Kosmos - May 28th, 2021
- An unusual addition to Californias 2022 ballot - CalMatters - May 28th, 2021
- Stem Cell Therapy Los Angeles - Darrow Stem Cell Institute - February 14th, 2021
- Smart Stem Cells Made From Fat Have the Power to Heal - Freethink - February 14th, 2021
- Are Covid-19 vaccines safe for cancer patients? Here is what cancer experts say - CNN - February 14th, 2021
- The race to treat a rare, fatal syndrome may help others with common disorders like diabetes - Science Magazine - February 14th, 2021
- Arlo's Army needs stem cell donor as mum begs for help to save three-year-old's life - Glasgow Live - February 14th, 2021
- Arlo's Army: mum opens up on heartbreaking decision to make 3-year-old sick to save his life - Glasgow Live - February 14th, 2021
- Bone marrow transplant shows signs of curing brave little boy with one in a million condition - Shields Gazette - February 14th, 2021
- Canada's blood supply has a diversity problem and people are dying because of it - CBC.ca - February 2nd, 2021
- State-of-the-Art Treatments Garner University Foot and Ankle Institute Multiple Top Doctor Awards - Yahoo Finance - February 2nd, 2021
- Dean Tracy Johnson seeks to diversify the pipeline of future scientists and doctors - UCLA Newsroom - February 2nd, 2021
- Transforming optimism: finding new ways to treat rare cancers - Cancer Research UK - Science Blog - February 2nd, 2021
- Family of Belfast woman Eimear Gooderham (25) share memories and dealing with grief in special UTV programme - Belfast Telegraph - February 2nd, 2021
- Doctor: COVID-19 cases will continue to slowly go down, but were not out of the woods - Yahoo Money - January 23rd, 2021
- Global Precision Medicine Market With COVID 19 Impact Analysis| Leading Players In-depth Analysis Research Report Foresight to 2027 - KSU | The... - January 23rd, 2021
- Leading Urologist Doubles Down on CaverStem Regenerative Stem Cell Procedure for Treatment of Erectile Dysfunction in Men - PRNewswire - January 22nd, 2021
- Sisters who organised an Ilkley fundraising ball are to be honoured - Wharfedale Observer - January 22nd, 2021
- Medical Doctor: Roes Overlooking of the Consensus of Societal Morality and Science Reverberates to This Day - National Catholic Register - January 22nd, 2021
- DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL)... - January 22nd, 2021
- Seattle researchers find clues for treatments that could eliminate HIV in infected patients - GeekWire - January 14th, 2021
- Flow Cytometry Market is Projected to Reach a Value of US$8100 Mn by the End of 2025 - KSU | The Sentinel Newspaper - January 14th, 2021
- Doctors diagnosed a Suffolk teen with a rare condition. Now, his mom is part of the solution - 13newsnow.com WVEC - January 12th, 2021
- Cassville club assists 2 families as they recover from illness - telegraphherald.com - January 12th, 2021
- The 26 billion-dollar startups to watch that are revolutionizing healthcare in 2021 - Business Insider - January 12th, 2021
- Global Precision Medicine Market 2020 Overview By Size, Share, Trends, Growth Factors and Leading Players With Detailed Analysis of Industry Structure... - January 12th, 2021
- More than 250 articles and a book later, the Valley Doctor bids adieu - San Lorenzo Valley Press-Banner - January 12th, 2021
- Groundbreaking Treatment for Severe COVID-19 Using Stem Cells It's Like Smart Bomb Technology in the Lung - SciTechDaily - January 5th, 2021
- New combo therapy offered against refractory T-cell lymphoma - Korea Biomedical Review - January 5th, 2021
- Hair Growth Treatment Secrets Bollywood Will Never Tell You About - Times of India - January 5th, 2021
- Are metabolic hormones the next frontier in cancer treatment? - MedCity News - January 5th, 2021
- Limerick toddler to wait six months for trial cancer treatment after family raises over 400,000 - Extra.ie - January 5th, 2021
- West Lothian mum fighting for her life after back pain turned out to be terminal blood cancer - Edinburgh Live - January 5th, 2021
- MorphoSys and Incyte Announce the Acceptance of the Swissmedic Marketing Authorization Application for Tafasitamab - Yahoo Finance UK - January 5th, 2021
- A Wish Come True urges plungers to dump a bucket of ice water on themselves for this year's fundraiser - Fall River Herald News - December 26th, 2020
- Ashley Cain says over 80,000 people registered for stem cell donation in 48 hours after appeal to save baby - The Sun - December 22nd, 2020
- The 11 most mind-blowing, awe-inspiring health discoveries and innovations of 2020 - Business Insider - Business Insider - December 22nd, 2020
- 3-year-old patient successfully treated for rare fatal disease- familial Hemophagocytic lymphohistiocytosis (HLH) at Fortis Hospital Shalimar Bagh -... - December 22nd, 2020
- Startups are racing to reproduce breast milk in the lab - MIT Technology Review - December 22nd, 2020
- Hand weakness: Causes, symptoms, treatment, and seeking help - Medical News Today - December 22nd, 2020
- Gujarat Issues Health Advisory On Fungal Infection With "50% Mortality Rate" - NDTV - December 22nd, 2020
- A side-by-side comparison of the Pfizer/BioNTech and Moderna vaccines - STAT - December 22nd, 2020
- City of Hope Doctors Present Innovative Therapies to Better Treat Blood Cancers at American Society of Hematology Virtual Conference - Business Wire - December 9th, 2020
- Medical technologies that will disrupt (and improve) healthcare in the 2020s - Universe.byu.edu - December 9th, 2020
- Community Cord Blood Banking saves life of child with aplastic anaemia - The Hindu - November 20th, 2020
- Arya Lloyd: Father launches global search for blood stem cell donor to save his 12-year-old daughter - Sky News - November 20th, 2020
- Blood Cancer: Science Reveal Five Easily Missed Signs of Leukemia - Science Times - November 20th, 2020
- Karnataka:Community cord blood banking emerges as lifesaver - United News of India - November 18th, 2020
- How CAR-T Cell Therapy is Being Used in the Field of Blood Cancer Treatment - Curetoday.com - November 16th, 2020
- Election results for California Propositions 14, 18, 23, and 24 - FOX 11 Los Angeles - November 16th, 2020
- Cell Separation Beads Market to Witness Robust Expansion Throughout the Forecast Period 2018-2028 - The Daily Philadelphian - November 16th, 2020
- Fight for the rights of unborn - The Daily Telegram - November 11th, 2020
- Genetic Mechanism Identified in Neonatal Diabetes Could Offer Insights into Other Forms of the Disease - Genetic Engineering & Biotechnology News - November 11th, 2020
- Doctors Debate: Is Intensive or Low-Intensity Chemotherapy Plus BCR-ABL TKI Therapy Best for Treatment of Ph+ ALL? - Targeted Oncology - November 11th, 2020
- Record number of stem cell donors apply after Ex On The Beach star plea - expressandstar.com - November 11th, 2020
- Bisbee: A commitment to health care initiatives The Journal Record - Journal Record - November 11th, 2020