Health TED Talks
Will the next generation think about diseases like Alzheimers and diabetes the way we think about polio and the whooping cough? Susan Solomon, the co-founder of the New York Stem Cell Foundation (NYSCF), certainly hopes so. In this fascinating talk from TEDGlobal 2012, Solomon delves into the foundations work on research with stem cells, which she calls the black boxes for diseases.
[Stem cells] are our bodies own repair kits. They are pluripotent, which means they can morph into all of the cells in our bodies, says Solomon. Right now there are some really extraordinary things that we are doing with stem cells that are completely changing the way we model disease, our ability to understand why we get sick and even develop drugs. But this field has been under siege, politically and financially.
While much of the fray is about embryonic stem cells still the gold standard when it comes to cells Solomon explains that another type of pluripotent stem cell (called iPS cells) can now be created by, essentially, reprogramming skin cells. These cells hold great promise for allowing researchers to see how diseases develop in humans, rather than in rodents.
Currently, developing a drug takes an average of 13 years, costs $4 billion, and has a 99% failure rate. And because its impossible to test a new drug on a large and representative sample of the human population, even a drug that tests well with many people will have side-effects for others, based on their genetic makeup. This is a problem thats sometimes not apparent until the drug is on the market and being prescribed to patients like in the tragic case of Vioxx.
Thats a terrible business model, but also is a horrible social model,she says. The way weve been developing drugs is essentially like going into a shoe store and no one asking what size you are They just say, Well, you have feet. Here are shoes.
From the TEDGlobal stage, Solomon outlined an exciting new approachher team at NYSCF has developed a machine that creates stem cell lines that, until now, had to be crafted by hand. NYSCF expects to produce 2,500 stem cell lines by the end of the year. The idea is to eventually produce a comprehensive array of 25,000 stem cell lines which act like avatars for a wide sample of people that researchers would have access to as they test new drugs.This could help avoid disasters and also let people know ahead of time of what side-effects they, specifically, can expect with a given medicine.
Two months after her talk, Solomon tells the TED Blog that interest in NYSCF work is growing. Pointing to a recent article in The New York Times about how future lung cancer treatments could be tailored to individuals, Solomon said, Its really the leading edge of where this field is going.
But Solomon stressed that it will be extremely difficult to change the current systems of drug development.
All the established companies have been using mouse-and-rodent testing forever, she said. A lot of peoples careers are staked to a method that is outdated. Its like the tech sector; this is really the high-tech sector for biomedical research.
To hear more about the NYSCF, watch Solomons talk. Below, watch 9 more talks about the incredible promise of stem cells.
Susan Lim: Transplant cells, not organsAs a woman, surgeon Susan Lim had to fight for the right to perform the first liver transplant in Asia. But she began to question the morality of such work given that with donor organs in such short supply many are coerced or forced to donate. Lim began looking at another approach: transplanting cells, rather than organs. In this talk, given at the INK Conference, she describes her work with adult stem cells derived from fat.
Daniel Kraft invents a better way to harvest bone marrowPediatrician and stem cell researcher Daniel Kraft has created a device to collect bone marrow in a way that is far less painful for both the patient and the doctor. In this talk from TED2009, Kraft shows how the stem cells found in this marrow could be used to treat heart disease and Parkinsons.
Eva Vertes: Do stem cells cause cancer?Microbiology prodigy Eva Vertes was 19 years old when she spoke at TED2005 about a theory that cancer might be a repair response to damaged stem cells in the lungs, liver, bones, etc. The implication she is testing? Its possible, although far-fetched, that in the future we could think of cancer being used as a therapy.
Alan Russell: The potential of regenerative medicineNot for the squeamish, in this talk from TED2006, medical futurist Alan Russell shows a video of stem cells being removed from a patients hip and injected directly into their heart and how this procedure has gotten much more precise over a short time. Such cell regeneration therapies will keep improving, Russell says.
Noel Bairey Merz: The single biggest health threat women faceWhile heart disease is often thought of as a male disease, Noel Bairey Merz explains that it is actually the biggest killer of women. In this talk from TEDxWomen 2011, Merz gives a call to arms for women to think of heart disease in the same way we do breast cancer, and talks about some exciting possibilities for treatment, including stem cell therapy.
Daniel Kraft: Medicines future? Theres an app for thatKraft, chair of the FutureMed program at Singularity University, talks about some of the big innovations coming down the pipeline in medicine. Near the end of this talk given at TEDxMaastricht, Kraft talks about cancer stem cells and how understanding them could lead to an era of personalized oncology the ability to leverage all of this data together, analyze the tumor and come up with a real, specific cocktail for the individual patient.
Juan Enriquez: The next species of humanFuturist Juan Enriquez believes that some big changes are coming, and that the next generation of humans could potentially be considered a different species. Why? In this talk from TED2009, he looks at the ability to engineer both cells and tissue, and describes some shocking ways researchers are using stem cells.
Kevin Stone: The bio-future of joint replacementArthritis affects more adults than cancer, says Kevin Stone in this talk from TED2010. While therapies using human tissue have been very promising in helping joint damage, there simply isnt enough donor tissue to go around. Stone explains a process which uses cartilage from a pig, loaded with a persons own stem cells, to ease pain and immobility.
Iain Hutchison: Saving facesIn this talk from TEDGlobal 2010 which contains some images of badly injured and disfigured faces that may be disturbing facial surgeon Iain Hutchison gives a look at his groundbreaking work. Towards the end of the talk, he describes an promising area of research tissue engineering which uses a patients own stem cells, taken from their hip, to help heal facial damage.
See the original post here:
10 talks on the future of stem cell medicine | TED Blog
- New Progress in Stem-Cell-Free Regenerative Medicine - May 26th, 2019
- The Stem Cell Theory of Cancer | Ludwig Center | Stanford ... - May 26th, 2019
- Ansary Stem Cell Institute | Department of Medicine - March 10th, 2019
- PRP vs. Stem Cell Therapy in Medicine | NSI Stem Cell - March 9th, 2019
- Top Stem Cell Conferences | Stem Cell Research 2019 ... - March 8th, 2019
- Bone Marrow & Stem Cell Transplant | Weill Cornell Medicine - March 7th, 2019
- Stem Cell | Regenerative medicine | 2019 | Conference ... - January 29th, 2019
- Original Medicine Wellness Center - Functional Medicine ... - January 28th, 2019
- Stem Cell Medicine Licenses Exosome Technology for ... - January 11th, 2019
- Stem Cell Medicine | Murdoch Children's Research Institute - November 30th, 2018
- FAQs - Ocean Springs, MS - Gulf Coast Stem Cell ... - November 14th, 2018
- Hematopoietic stem cell - Wikipedia - November 14th, 2018
- Stem Cell Conferences | Regenerative Medicine Conferences ... - November 12th, 2018
- Stem Cell Conferences | Regenerative Medicine Meetings |Gene ... - November 12th, 2018
- Stem Cell Regenerative Medicine Conferences 2018 Zurich ... - November 2nd, 2018
- Biologic Stem Cell Medicine and Therapy | RestorePDX - November 1st, 2018
- Stem Cell Therapy NYC, Regenerative Medicine Injections ... - July 11th, 2018
- Stem Cell Therapy San Antonio TX | Alternative ... - October 12th, 2017
- Human skin cells transformed directly into motor neurons - Washington University School of Medicine in St. Louis - September 8th, 2017
- Cambridge Enterprise and Qkine to drive stem cell and regenerative medicine research - Business Weekly - September 2nd, 2017
- FDA announces actions regarding stem cell treatments - Lexology (registration) - September 1st, 2017
- Six Japanese arrested over medical treatments using blood taken from umbilical cords, which are popular with Chinese ... - South China Morning Post - September 1st, 2017
- In utero stem cell transplants may replace riskier childhood transplants for multiple conditions - Medical Xpress - August 31st, 2017
- Human Stem Cells Fight Parkinson's Disease in Monkeys - Scientific American - August 31st, 2017
- Puppies benefit from stem cell treatment for children with spina bifida - University of California - August 31st, 2017
- Why Doug Baldwin went to England for stem-cell therapy - The News Tribune (blog) - August 29th, 2017
- FDA moves to curb dangerous stem cell clinics - Philly.com - August 29th, 2017
- Stem Cell Treatment Helps Puppies With Spina Bifida - Technology Networks - August 29th, 2017
- US FDA steps up scrutiny of stem cell therapies - Reuters - August 29th, 2017
- ICMR's stem cell research guidelines soon to be released - ETHealthworld.com - August 29th, 2017
- Stem cell treatment for children with spina bifida helps dogs first - Phys.Org - August 25th, 2017
- 'Beating Heart' Patch Offers New Hope for Desperately Ill Patients - NBCNews.com - August 25th, 2017
- Yeargan Uses Patients Own Cells To Heal - Greater Wilmington Business Journal - August 25th, 2017
- State's Stem Cell Agency Awards $18.2 Million Grant for B Cell Cancer Clinical Trial - UC San Diego Health - August 25th, 2017
- Researcher Seeks to Unravel the Brain's Genetic Tapestry to Tackle Rare Disorder - University of Virginia - August 23rd, 2017
- Mouse Model of Human Immune System Inadequate for Stem Cell Studies - Technology Networks - August 23rd, 2017
- Mouse model of human immune system inadequate for stem cell ... - Medical Xpress - August 22nd, 2017
- Stem Cell Treatments for Lung Diseases Advance - Healthline - Healthline - August 22nd, 2017
- UTMB lung experiment flies into space - Austin American-Statesman - August 22nd, 2017
- These Six Startups From Y Combinator's Demo Day 1 Are Ready to Transform Our World - Futurism - August 22nd, 2017
- Novel stem cell-derived model created of inflammatory neurological disorder - Medical Xpress - August 10th, 2017
- Test results after stem cell transplant for multiple myeloma can ... - Medical Xpress - August 10th, 2017
- Are Stem Cell Companies Abusing ClinicalTrials.gov? - PLoS Blogs (blog) - August 10th, 2017
- Okyanos Center for Regenerative Medicine to Hold Stem Cell Symposium in Freeport - Benzinga - August 9th, 2017
- About Us - Stem Cell Medicine :: STEM CELL MEDICINE LTD. - August 4th, 2017
- Engineered Skin Cells Control Type 2 Diabetes in Mice: Study - Sioux City Journal - August 4th, 2017
- Qkine synchronises licensing deal - Global University Venturing - August 4th, 2017
- Honor for pioneering equine stem cell researcher - Horsetalk - August 3rd, 2017
- Speculator makes case for candidates to end years of hurt for stem cell investors - The Pharma Letter (registration) - July 31st, 2017
- Dozens of US clinics sell unproven stem cell therapies for heart failure - Reuters - July 30th, 2017
- The Big Deal About Stem Cell Therapies and Regenerative Medicine - PR Newswire UK (press release) - July 30th, 2017
- Regenexx Announces Successful Merger with Harbor View Medical - OrthoSpineNews - July 12th, 2017
- Stem Cells Guided by Electric Fields May Offer New Therapies for ... - Genetic Engineering & Biotechnology News (press release) - July 12th, 2017
- Danvers health group offers alternative solution to surgery - Wicked Local North of Boston - July 4th, 2017
- LMU-DCOM student selected for research project - The Middlesboro Daily News - July 1st, 2017
- Siberian scientists say stem cells can treat varicose veins - Russia Beyond the Headlines - June 30th, 2017
- Stemcell Stroke hold the key to changing the face of medicine forever. - Checkbiotech.org (press release) - June 30th, 2017
- A New Path for US Stem Cell Inc (OTCMKTS:USRM) - The Oracle Dispatch - June 28th, 2017
- UIC Launches Stem Cell, Regenerative Medicine Center - Chicago Tonight | WTTW - June 13th, 2017
- Stem Cell Research at Johns Hopkins Medicine: Spinal ... - May 29th, 2017
- INTERNATIONAL REGENERATIVE MEDICINE COMMUNITY TO ... - GlobeNewswire (press release) - May 13th, 2017
- Fighting arthritis: Researchers edit stem cells to fight inflammation - Kasmir Monitor - April 29th, 2017
- California's $3-billion bet on stem cells faces final test - Nature.com - April 29th, 2017
- Streamlining Stem Cell Manufacturing - Genetic Engineering & Biotechnology News (press release) - April 24th, 2017
- Cord Blood Association Names STEM CELLS Translational ... - Benzinga - April 1st, 2017
- 3 women blinded in stem cell clinical trial - AOL - March 17th, 2017
- Stem Cell Therapies for Degenerative Disc Disease - Clinical Pain Advisor (registration) - March 17th, 2017
- UC Davis licenses novel compound that helps stem cells regenerate bone - HealthCanal.com (press release) (blog) - March 4th, 2017
- Study of SanBio's Stem Cell Treatment for Stroke Receives Innovation Award from American Heart Association - Yahoo Finance - February 27th, 2017
- World-Renowned Stem Cell Transplantation Expert joins Cellect's Advisory Board - P&T Community - February 27th, 2017
- Obesity reprograms muscle stem cells -- ScienceDaily - Science Daily - February 23rd, 2017
- Early-stage study validates Cellect Bio's method of stem cell selection; shares ahead 19% - Seeking Alpha - February 22nd, 2017
- Cancer stem cell - Wikipedia - February 4th, 2017
- Adult Stem Cell Medicine Technology | Asymmetrex - November 27th, 2016
- Duke Stem Cell and Regenerative Medicine Program - November 2nd, 2015
- Eli and Edythe Broad Center for Regenerative Medicine and ... - October 22nd, 2015
- California Stem Cell Report - October 17th, 2015
- Hair Restoration Treatment Uses Novel Stem Cell Therapy ... - October 12th, 2015
- CD47 - Research and Clinical Trials - Institute for Stem ... - September 25th, 2015
- Stem Cells News -- ScienceDaily - September 8th, 2015