Little Arlo McArthur has spent his short life fighting.
No one knows better than his mum Nicole just how tough this little warrior is.
Diagnosed with a deadly blood disorder at just 10 weeks old, the three-year-old desperately needs a stem cell transplant to save his life.
And as the campaign to encourage males between 16 and 30 to volunteer to be tested to see if they are a match gathers pace, Nicole has opened up in heartbreaking detail about the harrowing battle to save Arlo.
She told Glasgow Live: "This is every parents worst nightmare. I cannot lose my son. We have such a fight ahead of us.
"He's doing really well at the moment but it's really scary looking at him, knowing he is so vulnerable. It hurts us so much."
It was only two weeks after bringing their baby boy home in 2017 that Nicole and husband Ian discovered something was wrong with him.
"We rushed him to A&E after he vomited a blood clot." Nicole recalls. "Doctors initially diagnosed a severe cows milk allergy and sent us home. Later he vomited again, and we found blood in his poo so we returned.
"It was suggested that it may be leukaemia as his platelets were so low. When they said that, I knew there was something deeply wrong. After that was ruled out, we waited ten more weeks for answers.
This was the point that I realised that doctors were only human, they are not God. They dont know everything: Its about eliminating all of these possibilities until they get to what it is. It was tough.
The Milngavie family spent weeks agonising in the dark and were offered leaflets on living without a diagnosis but kept in touch with medics.
One doctor mentioned that she thought his symptoms matched up with a rare condition, but did not want to define it to Nicole until the test results were confirmed.
After asking another member of staff, the sickened mum discovered they were testing her baby for Wiskott Aldrich Syndrome.
She said: "I Googled it when I got home and I was utterly traumatised to learn that the life expectancy for a child with this condition was five. I was beside myself.
"My friends and family were saying dont be silly and stay positive. I was praying and hoping it wasnt, but I knew in my gut it was what Arlo had."
Nicola steeled herself for the worst, but nothing could have prepared her for the moment she was given the bad news at the hospital. She broke down before the doctor had finished delivering the diagnosis.
Worse still, she was alone as her husband was unable to take any more time off work.
I was complete mess I was in full crazy mode, crying. I had to deliver the news to my husband over the phone. I never imagined it would be like this," she said.
The doctor tried to calm me down and said we could get him a bone marrow transplant. I didnt even know what that was before then.
Wiskott Aldrich Syndrome is a rare genetic immunodeficiency disease that keeps a child's immune system from functioning properly. It also makes it difficult for a child's bone marrow to produce platelets, making them prone to bleeding.
Its estimated there are between 1 and 10 cases per million males worldwide. Arlo was only the third case at Queen Elizabeth University Hospital.
A 10/10 donor match was found for him on December 22 the best Christmas present ever and shipped over from the US. The family battled to have it transported to Scotland from Heathrow in an Uber after flights were grounded during a snow storm.
The baby's transplant was successful, and the cells were engrafting. But that started to change, and his engraftment started to drop with each check in.
He also contracted severe sepsis and began suffering from seizures and it emerged entophilitis, a form of meningitis, had entered his brain. His neck lolled and his eyes danced around. He was taken into intensive care after being discharged.
We thought he might have had brain damage. It sounds terrible but we were accepting of that. Well take anything as long as hes with us. Well deal with what we have to. We just wanted him to live. Thankfully the symptoms resolved themselves.
If he didnt have that within six months, he wouldnt have made it to his first birthday. He was very, very sick.
Arlo urgently needs to find a young, male, donor aged 16-30. His back-up is his dad, who is a half-match.
Nicole explains that the success rate is higher for children under five in a healthier condition. When they find the match, the toddler will have to undergo high-dose chemotherapy to break down his immune system to allow the transplant to take place. He last had this when he was six months old.
One nurse described it to me as taking the body as close to death as they possibly can and rebuilding it. Its really harsh on the body its basically a poison," she said.
He really wasnt well the first time and he ended up on morphine for the pain. He had mucositis all the way from his throat to his gut and had to be fed through a tube to bypass his stomach. It was horrible.
"But if he doesnt do this as soon as he can, his immune system wont be able to withstand it. He could be at risk of leukaemia. I know hes a ticking time-bomb.
While doctors are hopeful that the next transplant will help Arlo, they warned the family to brace themselves for it not working out again. The mortality rate for a transplant is also around 20 per cent but Nicole said its a risk the family is willing to take to give their boy his best chance.
She said: The doctors do speak to you and say You do know if we dont get the result youre looking for things can go wrong. You have to sign paperwork to confirm that you know this could result in death.
So much can happen. You could undergo a transplant to fix one thing, and come out with another.
Once I played devils advocate and asked the doctor what Arlos life would be like if we chose not to take the transplant.
"He told me that Arlo would have a poor quality of life and they could possibly get him to his teenage years, maybe even his late teens. But it 'wouldnt be a nice way to live.' I said thats not an alternative. "
She added: To make him sick and risk his life to make him better all at the same time is heartbreaking. But theres that chance he could live a better life and thats what we are fighting for.
If we lose Arlo in the process, we know that we have done everything in our power to give him a normal life that we possibly can. That's in God's hands. It is our only option.
To find out how you can can join the register and help the fight to save little Arlo and others just like visit Anthony Nolan's website here.
- Indiana's top doctors frustrated about the state's COVID-19 vaccination rate - 953mnc.com - August 31st, 2021
- Should You Get a COVID Booster Shot? Our Doctor Explains - Articles and Videos, COVID-19, Featured, Health Topics - Hackensack Meridian Health - August 31st, 2021
- OpRegen: tackling the leading cause of blindness with cell replacement - Clinical Trials Arena - August 31st, 2021
- I blamed stress for my three-month period but it turned out to be much more sinister... - The Sun - August 31st, 2021
- New fault lines emerge in Car-T therapy - Vantage - August 31st, 2021
- When aid-in-dying means you have to go before youre ready - Monterey Herald - August 31st, 2021
- Dr. Death Season 1 Review: Truth continues to be stranger than fiction. - Times of India - August 31st, 2021
- Circulating Tumor Cells (CTC) Diagnostics Market is expected to Account for Over US$ 9.5 Million in - PharmiWeb.com - August 31st, 2021
- COVID-19 in children with cancer: Severe disease and disrupted treatment - Markets Insider - August 31st, 2021
- Sophomore saves sister's life with stem cell donation - University of Miami - August 5th, 2021
- Myelodysplastic Syndrome Treatment Options - Healthline - August 5th, 2021
- Gold River Productions, Inc. (GRPS) Appoints Michael Berkowitz to spearhead the Rejuvenation Division with StemSpa - Yahoo Finance - August 5th, 2021
- Colin Jackson health: Im in constant pain Athlete to undergo stem cell therapy to help - Express - August 5th, 2021
- The Basics of MDS: Diagnosis and Staging - Curetoday.com - August 5th, 2021
- Blood donation clinic will honour life of Jocelyn McGlynn - Chatham Daily News - August 5th, 2021
- Pharming Group reports financial results for the first half of 2021 - PRNewswire - August 5th, 2021
- Symptoms of seizures: Early signs, post-seizure, and more - Medical News Today - August 5th, 2021
- Lymph nodes: Purpose, location, and disease warning signs - Medical News Today - June 8th, 2021
- Teesside baby will be third in country to have ground breaking complex cancer treatment - Teesside Live - June 8th, 2021
- Brave Nathaniel Nabena, 9, all smiles as he has life-saving procedure - thanks to you - The Mirror - June 8th, 2021
- Local veterinary clinics offer integrated care options for pets - williamsonherald.com - June 8th, 2021
- Blood cancer and leukaemia: UAE oncologist urges public to spot the symptoms - The National - June 8th, 2021
- Replotting the human: the thorny ethics of growing babies outside the womb - Prospect - June 8th, 2021
- Crossroads of life: Jordan Reed's journey through concussions, injuries and post-NFL healing - The Athletic - June 8th, 2021
- B-cell acute lymphoblastic leukemia: What to know - Medical News Today - May 28th, 2021
- Chronic lymphocytic leukemia and stomach pain: What is the link? - Medical News Today - May 28th, 2021
- Top 12 Disruptive Gene and Cell Therapy Technologies Announced - GlobeNewswire - May 28th, 2021
- BlueRock and Senti Collaborate to Build Smarter, Disease-Fighting Cell Therapies - BioSpace - May 28th, 2021
- Living with blood cancer - Lara Said - Times of Malta - May 28th, 2021
- 3D Printed Stem Cells Could Revolutionize Neuroscience, Aid Treatment and Understanding of Neural Diseases - Science Times - May 28th, 2021
- In the War on Cancer, Science Is Winning - The Wall Street Journal - May 28th, 2021
- Whats Causing Black Fungus? Here Is What The Doctors Have To Say - The Logical Indian - May 28th, 2021
- University of Pittsburgh Won't Explain its Planned Parenthood Ties | Opinion - Newsweek - May 28th, 2021
- Trial treatment with a mythologically-inspired name saves life of young man diagnosed with multiple myeloma - Neos Kosmos - May 28th, 2021
- An unusual addition to Californias 2022 ballot - CalMatters - May 28th, 2021
- Stem Cell Therapy Los Angeles - Darrow Stem Cell Institute - February 14th, 2021
- Stem Cell Transplants: A Lifesaving Treatment for Cancer ... - February 14th, 2021
- Smart Stem Cells Made From Fat Have the Power to Heal - Freethink - February 14th, 2021
- Are Covid-19 vaccines safe for cancer patients? Here is what cancer experts say - CNN - February 14th, 2021
- The race to treat a rare, fatal syndrome may help others with common disorders like diabetes - Science Magazine - February 14th, 2021
- Arlo's Army needs stem cell donor as mum begs for help to save three-year-old's life - Glasgow Live - February 14th, 2021
- Bone marrow transplant shows signs of curing brave little boy with one in a million condition - Shields Gazette - February 14th, 2021
- Canada's blood supply has a diversity problem and people are dying because of it - CBC.ca - February 2nd, 2021
- State-of-the-Art Treatments Garner University Foot and Ankle Institute Multiple Top Doctor Awards - Yahoo Finance - February 2nd, 2021
- Dean Tracy Johnson seeks to diversify the pipeline of future scientists and doctors - UCLA Newsroom - February 2nd, 2021
- Transforming optimism: finding new ways to treat rare cancers - Cancer Research UK - Science Blog - February 2nd, 2021
- Family of Belfast woman Eimear Gooderham (25) share memories and dealing with grief in special UTV programme - Belfast Telegraph - February 2nd, 2021
- Doctor: COVID-19 cases will continue to slowly go down, but were not out of the woods - Yahoo Money - January 23rd, 2021
- Global Precision Medicine Market With COVID 19 Impact Analysis| Leading Players In-depth Analysis Research Report Foresight to 2027 - KSU | The... - January 23rd, 2021
- Leading Urologist Doubles Down on CaverStem Regenerative Stem Cell Procedure for Treatment of Erectile Dysfunction in Men - PRNewswire - January 22nd, 2021
- Sisters who organised an Ilkley fundraising ball are to be honoured - Wharfedale Observer - January 22nd, 2021
- Medical Doctor: Roes Overlooking of the Consensus of Societal Morality and Science Reverberates to This Day - National Catholic Register - January 22nd, 2021
- DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) Becomes the First FDA-Approved Treatment for Patients with Newly Diagnosed Light Chain (AL)... - January 22nd, 2021
- Seattle researchers find clues for treatments that could eliminate HIV in infected patients - GeekWire - January 14th, 2021
- Flow Cytometry Market is Projected to Reach a Value of US$8100 Mn by the End of 2025 - KSU | The Sentinel Newspaper - January 14th, 2021
- Doctors diagnosed a Suffolk teen with a rare condition. Now, his mom is part of the solution - 13newsnow.com WVEC - January 12th, 2021
- Cassville club assists 2 families as they recover from illness - telegraphherald.com - January 12th, 2021
- The 26 billion-dollar startups to watch that are revolutionizing healthcare in 2021 - Business Insider - January 12th, 2021
- Global Precision Medicine Market 2020 Overview By Size, Share, Trends, Growth Factors and Leading Players With Detailed Analysis of Industry Structure... - January 12th, 2021
- More than 250 articles and a book later, the Valley Doctor bids adieu - San Lorenzo Valley Press-Banner - January 12th, 2021
- Groundbreaking Treatment for Severe COVID-19 Using Stem Cells It's Like Smart Bomb Technology in the Lung - SciTechDaily - January 5th, 2021
- New combo therapy offered against refractory T-cell lymphoma - Korea Biomedical Review - January 5th, 2021
- Hair Growth Treatment Secrets Bollywood Will Never Tell You About - Times of India - January 5th, 2021
- Are metabolic hormones the next frontier in cancer treatment? - MedCity News - January 5th, 2021
- Limerick toddler to wait six months for trial cancer treatment after family raises over 400,000 - Extra.ie - January 5th, 2021
- West Lothian mum fighting for her life after back pain turned out to be terminal blood cancer - Edinburgh Live - January 5th, 2021
- MorphoSys and Incyte Announce the Acceptance of the Swissmedic Marketing Authorization Application for Tafasitamab - Yahoo Finance UK - January 5th, 2021
- A Wish Come True urges plungers to dump a bucket of ice water on themselves for this year's fundraiser - Fall River Herald News - December 26th, 2020
- Ashley Cain says over 80,000 people registered for stem cell donation in 48 hours after appeal to save baby - The Sun - December 22nd, 2020
- The 11 most mind-blowing, awe-inspiring health discoveries and innovations of 2020 - Business Insider - Business Insider - December 22nd, 2020
- 3-year-old patient successfully treated for rare fatal disease- familial Hemophagocytic lymphohistiocytosis (HLH) at Fortis Hospital Shalimar Bagh -... - December 22nd, 2020
- Startups are racing to reproduce breast milk in the lab - MIT Technology Review - December 22nd, 2020
- Hand weakness: Causes, symptoms, treatment, and seeking help - Medical News Today - December 22nd, 2020
- Gujarat Issues Health Advisory On Fungal Infection With "50% Mortality Rate" - NDTV - December 22nd, 2020
- A side-by-side comparison of the Pfizer/BioNTech and Moderna vaccines - STAT - December 22nd, 2020
- City of Hope Doctors Present Innovative Therapies to Better Treat Blood Cancers at American Society of Hematology Virtual Conference - Business Wire - December 9th, 2020
- Medical technologies that will disrupt (and improve) healthcare in the 2020s - Universe.byu.edu - December 9th, 2020
- Community Cord Blood Banking saves life of child with aplastic anaemia - The Hindu - November 20th, 2020
- Arya Lloyd: Father launches global search for blood stem cell donor to save his 12-year-old daughter - Sky News - November 20th, 2020
- Blood Cancer: Science Reveal Five Easily Missed Signs of Leukemia - Science Times - November 20th, 2020