The coronavirus pandemic has dominated the headlines and our daily lives for over a year. Medical News Today has covered this fast-moving, complex story with live updates about the latest news, interviews with experts, and an ongoing investigation into the deep racial disparities that COVID-19 has helped unmask.
However, this has not stopped us from publishing hundreds of fascinating stories on a myriad of other topics.
We begin this weeks Recovery Room with new findings of research into Parkinsons disease that may also have wider implications for the treatment of other neurodegenerative diseases and cancer.
Next comes a detailed exploration of the role that carbohydrates play in the development of diabetes. Its a complex picture, and a low carb diet may not be the panacea that some claim it to be.
We also have two reports about the influence of artificial intelligence (AI) on medical research, as well as articles covering breakthroughs in HIV prevention, sickle cell disease reversal, and heart tissue regeneration.
Finally, we look at research confirming that a steady income is good for self-confidence but may have a minimal effect on feelings about other people.
We highlight this research below, along with several other recent stories that you may have missed amid all the COVID-19 fervor.
We begin with the most-read article of the past week, with more than 124,000 page views: our report on new insights into a biochemical pathway that drives Parkinsons disease. The discovery may help scientists develop treatments for this disease, as well as type 2 diabetes and cancer.
Parkin is a protein that plays a key role in maintaining cellular energy by removing damaged mitochondria, a process known as mitophagy. The new research indicates that the biochemical pathway that activates Parkin is shorter than previously thought, which helps explain how Parkin triggers mitophagy within minutes of cellular distress occurring.
Type 2 diabetes, cancer, and some neurodegenerative diseases stem from metabolic dysregulation in damaged mitochondria, so the Parkin pathway is likely to have a role in their progression, too.
Click below to learn more about how drugs developed to treat diabetes may also be used to treat Parkinsons, or click here to visit our new Parkinsons disease resource page.
Learn more here.
Our new article exploring the role that carbohydrates play in diabetes was also very popular, with over 117,000 page views so far this week.
First, our editors looked at the relationship between carb consumption, insulin, and blood sugar. They also explored how many carbs a person with diabetes should consume, good carbs, foods to include in the diet and foods to avoid, and the effects of specific diets, including a low carb diet.
The takeaway is that not all carbs are bad for a person with diabetes, but the focus should be on healthy, whole foods rather than processed foods and those high in refined sugars.
Learn more here.
Good nutrition is important at every stage of life. This week, we published a new article on the critical role of nutrition in a childs brain development, especially in the first 3 years.
Our editors first list a variety of healthy brain foods. They then share ideas for breakfasts that may help a child stay focused at school and snacks for children to try while studying. Click the link below to see the variety of foods and nutrients that should be part of every childs diet.
Learn more here.
A reliable HIV vaccine has been difficult to develop because there are so many strains of the virus, around 50 million, according to one researcher involved in a new phase 1 clinical trial.
The new course of vaccines is designed to activatebroadly neutralizing antibodies (bnAbs) that target a wide variety of HIV strains. Only one very rare type of immune cell is able to produce bnAbs, and the vaccine activated these naive B cells in 97% of participants who received it, according to the researchers.
This novel technique could also be used to make vaccines for other diseases that have proven challenging for vaccine developers, including malaria, influenza, and hepatitis C.
Learn more here.
Two of this weeks articles highlighted how AI is being deployed to aid medical research.
First, we described ways that researchers are using powerful learning algorithms to model and predict how proteins behave in human cells. Existing AI technology used to process natural language was adapted to see if it could also predict protein language and expression.
The researchers made the technique available on a new web application, linked to in our article, that allows scientists to submit a protein sequence and view its predicted behavior.
Learn more here.
We also reported on how AI is being used to analyse the brain scans of thousands of people with multiple sclerosis (MS) in an effort to learn more about the disease.
The AI program, called SuStaIn, performed an unsupervised analysis of the brain scans and detected patterns that might otherwise have been missed. As a result, three new subtypes of the disease were identified, each presenting as different types of abnormalities in the brain.
These subtypes could be used to predict a persons response to different treatments. If this finding is supported by more clinical research, it could help ensure that the correct therapy is given at the correct time.
Learn more here.
This week, we reported on a new study that concludes that a drug that appears to reverse sickle cell disease in mice is safe for humans. The drug candidate, called FTX-6058, restored the ability to produce fetal hemoglobin.
Around 1 in 365 Black people in the U.S. are born with sickle cell disease, which is relatively rare in white people. Currently, the only cure is a stem cell or bone marrow transplant, but these are very risky. FTX-6058 will now be used in a phase 2 clinical trial that includes people with sickle cell disease, for the first time, by the end of this year.
Learn more here.
Unlike humans, adult zebra fish regenerate their hearts and other organs after injury. Until recently, the way that they do this has been unclear, but researchers are now looking more closely at the role that a protein called KLF1 plays in this remarkable ability.
Inhibiting the gene for KLF1 severely limited the ability of zebra fish to regenerate heart tissue. Investigating the role of KLF1 in human hearts will require much more work, but if the protein can help regenerate heart tissue after an injury in humans, it could be a game-changer in the treatment of heart disease.
Learn more here.
April is National Autism Awareness Month, and last weeks Recovery Room featured the experience of a parent who established a school following the diagnosis of her sons autism.
This week, MNT reported on a new approach to assessing autism spectrum disorder that focuses more on proficiency and growth than deficits in a childs development. Changing the narrative in this way could help develop a more constructive and holistic way to understand each childs unique requirements and help with the selection of therapies and interventions.
This approach is also better able to account for factors such as household income and other elements of social context, compared with measuring a childs progress against a rigid set of outcomes.
Learn more here.
Finally, this week, we reported on what claims to be the first study into the emotional benefits of living with a secure income. This large study tracked the emotional responses of 1.6 million people in 162 countries.
Its key findings are that people with a steady income are more likely to feel confident and proud of themselves and that these feelings can persist for decades. However, making more money did not appear to strengthen positive feelings about others, and nor did it affect feelings such as anger.
According to this research, earnings are only linked to some inward-facing emotions, so a societys affluence may not have as strong an influence on community harmony as policymakers might expect.
Learn more here.
We hope that this weeks Recovery Room has provided a taste of the stories that we cover atMNT. We will be back with a new selection next week.
We publish hundreds of new stories and features every month. Here are some upcoming articles that may pique our readers interests:
- Stemming the tide of stem-cell treatment scams - Houston Chronicle - July 22nd, 2021
- FDA gives speedy review to Bayer's Parkinson's stem cell therapy - - pharmaphorum - July 22nd, 2021
- John Theurer Cancer Center Investigators Participated in ZUMA-7 Study Showing Value of CAR T-Cell Therapy as Second-Line Treatment for Relapsed Large... - July 22nd, 2021
- Creative Medical Technology Holdings Announces MyeloCelz The Company's Second Regenerative Immunotherapy Product - PRNewswire - July 22nd, 2021
- Kadimastem Patent for cell selection of beta cells to Treat and Potentially Cure Diabetes was Granted in Japan - Yahoo Eurosport UK - July 22nd, 2021
- Bluebird, with little fanfare, is first to bring a second gene therapy to market - BioPharma Dive - July 22nd, 2021
- BlueRock Therapeutics Receives FDA Fast Track Designation for DA01 in the Treatment of Advanced Parkinson's Disease - Yahoo Finance - July 22nd, 2021
- ViaCyte Appoints Dr. Jon Wilensky as Head of Surgery - PRNewswire - July 22nd, 2021
- Emerging Quadruplets, Novel Targets, and Immunotherapy Advances Personalized Medicine in Multiple Myeloma - OncLive - July 22nd, 2021
- Beyond CAR-T: New Frontiers in Living Cell Therapies - UCSF News Services - July 7th, 2021
- Sleeper cells, cells of origin and hematopoietic stem cells - Brain Tumour Research - July 7th, 2021
- Marker Therapeutics Announces Completion of Safety Lead-In Portion of Phase 2 Study in Post-Transplant AML - PRNewswire - July 7th, 2021
- Researchers investigate whether stem cell therapy is safe and effective for treatment-resistant bipolar disease - Newswise - April 18th, 2021
- Stem Cell and Regenerative Therapy Market: Cell Therapy Segment to Dominate Global Market - BioSpace - April 18th, 2021
- First in the nation, FDA-approved Phase II mesenchymal stem cell therapy for Parkinson's disease begins - Newswise - April 18th, 2021
- Cellino Biotech developing tech to help scale stem cell therapies - MedCity News - April 18th, 2021
- Stem cell treatment needed to fight the good fight - Victoria Lookout - April 18th, 2021
- Being bionic: the future of regenerative medicine - Toronto Star - April 18th, 2021
- Treating chronic myeloid leukemia (CML): By phase and more - Medical News Today - April 18th, 2021
- Chemical conversion of human epidermal stem cells into intestinal goblet cells for modeling mucus-microbe interaction and therapy - Science Advances - April 18th, 2021
- Andres Isaias Combining Innovation and Excellence - Influencive - April 18th, 2021
- A Massive New Gene Editing Project Is Out to Crush Alzheimer's - Singularity Hub - April 18th, 2021
- Antibiotic Use Prior to Allogeneic Stem Cell Transplantation May Be Linked to Graft Vs Host Disease - Hematology Advisor - April 18th, 2021
- Mucopolysaccharidosis (MPS) Treatment Market Is Rising With Post COVID-19 Impact Analysis, Development, CAGR - Global Banking And Finance Review - April 18th, 2021
- The Governments Watchful Eye on Fraud Stemming from Stem Cell Therapy - JD Supra - April 4th, 2021
- Uprooting Cancer: Innovative Hydrogel Rapidly Reverts Cancer Cells Back to Cancer Stem Cells - SciTechDaily - April 4th, 2021
- Multiple sclerosis: Recent research on causes and treatments - Medical News Today - April 4th, 2021
- First CAR T-Cell Therapy for Multiple Myeloma: Abecma - Medscape - April 4th, 2021
- Vitro Biopharma Retains Leading Health Care Executive as Acting Director of Regulatory Affairs & Director - Benzinga - April 4th, 2021
- Allogeneic hematopoietic stem cell transplantation for therapy-related myeloid neoplasms following treatment of a lymphoid malignancy - DocWire News - April 4th, 2021
- Orca-T Offers an Alternative to HSCT With Improved Patient Experience - OncLive - April 4th, 2021
- Russell Health Highlighted in the Silicon Review's '50 Leading Companies of the Year 2021' - PRNewswire - April 4th, 2021
- Gracell Biotechnologies Announces Enrollment of First Patient in Registrational Phase 1/2 Clinical Study for GC007g, an Allogeneic CAR-T Cell Therapy... - April 4th, 2021
- LGL Leukemia: Overview, Symptoms, and Treatment - Healthline - April 4th, 2021
- Funding the Next Generation of Cancer Therapies - Genetic Engineering & Biotechnology News - April 4th, 2021
- RenovaCare Announces Organizational Changes and Appointment of New Officers - GlobeNewswire - April 4th, 2021
- Stem Cell Therapy Market expected to reach USD 16.51 Billion by 2025 KSU | The Sentinel Newspaper - KSU | The Sentinel Newspaper - March 8th, 2021
- Creative Medical Technology Holdings Publishes Efficacy in Pain Reduction and Mobility in Patients with Disc Degenerative Disc Using StemSpine... - March 8th, 2021
- New Controversy for Stem Cell Therapy That Repairs Spinal Cords - The Great Courses Daily News - March 8th, 2021
- Cell Therapy for Cartilage Regeneration Gets a Boost With Hyaluronic Acid Enriched Chondrocytes in a 3D Tissue Engineering Platform - Business Wire - March 8th, 2021
- Scar-Forming Cells Switch to Producing New Neurons that Promote Functional Recovery in Mice after Spinal Cord Injury - Genetic Engineering &... - March 8th, 2021
- Moderna Hires Harvard Stem Cell Researcher Jonathan Hoggatt as Director of Hematology: What You Need to Know - Yahoo Finance - March 8th, 2021
- Stem Cell Banking Market Report 2021 | Growth and Opportunities Analysis - BioSpace - February 19th, 2021
- Global Cell Therapy Biomanufacturing Market (2020 to 2025) - Featuring Lonza Group, Merck & Novartis Among Others - ResearchAndMarkets.com -... - February 19th, 2021
- Off-the-Shelf NK Immunotherapy Is Safe and Promising in B-Cell NHL With Chemotherapy and Transplant - Targeted Oncology - February 17th, 2021
- Braunschweig Makes the Case for Earlier Use of CAR T-Cell Therapy in DLBCL - OncLive - February 17th, 2021
- Creative Medical Technology Holdings Files Patent on Prevention of Organ Transplant Rejection using ImmCelz - PRNewswire - February 17th, 2021
- Lineage to Host Virtual OPC1 Investor & Analyst Day on February 22, 2021 - Business Wire - February 17th, 2021
- Novartis, Gates Foundation pursue a simpler gene therapy for sickle cell - STAT - February 17th, 2021
- CRISPR Therapeutics Provides Business Update and Reports Fourth Quarter and Full Year 2020 Financial Results - GlobeNewswire - February 17th, 2021
- Equillium Presents Positive Interim Clinical Data of Itolizumab in First-line Treatment of Acute Graft-Versus-Host Disease at the 2021 Transplantation... - February 14th, 2021
- Zebrafish reveal regenerative protein that could inspire new treatments for muscle-wasting diseases and aging - FierceBiotech - February 11th, 2021
- Stem cell study illuminates the cause of an inherited heart disorder | Penn Today - Penn Today - February 11th, 2021
- Neurons from patient blood cells enable researchers to test treatments for genetic brain disease - Brown University - February 11th, 2021
- Therapeutic Solutions International Acquires Stem Cell Therapy That Successfully Completed FDA Double Blind Placebo Controlled Efficacy Study for Lung... - February 11th, 2021
- The Role and Activation Mechanism of TAZ in Hierarchical Microgroove/N | IJN - Dove Medical Press - February 11th, 2021
- Stem Cell Therapy Market: Top 5 trends fueling the industry revenue through 2025 - BioSpace - February 9th, 2021
- Magenta Therapeutics to Present Additional Data from Phase 1 MGTA-145 Stem Cell Mobilization Program and Preclinical Updates on Targeting Conditioning... - February 9th, 2021
- Gamida Cell Presents Efficacy and Safety Results of Phase 3 Study of Omidubicel in Patients with Hematologic Malignancies at the 2021 TCT Meetings of... - February 9th, 2021
- Creative Medical Technology Holdings Recruits Internationally Renowned Kidney Expert to Scientific Advisory Board - PRNewswire - February 9th, 2021
- Jasper Therapeutics Announces Positive Data from Phase 1 Clinical Trial of JSP191 as Targeted Stem Cell Conditioning Agent in Patients with... - February 9th, 2021
- USC scientist Ya-Wen Chen receives American Lung Association grant to advance stem cell-based lung therapies - USC News - February 9th, 2021
- [Full text] Successful Use of Nivolumab in a Patient with Head and Neck Cancer Aft | OTT - Dove Medical Press - February 9th, 2021
- Responses to Liso-Cel Not Influenced by Prior Treatment With Anti-CD19 Agents in R/R Large B-Cell Lymphoma - Targeted Oncology - February 9th, 2021
- Drugs that trip cellular alarm could help clear out hibernating HIV - New Atlas - February 9th, 2021
- Leukemia in children: Symptoms, causes, treatment, outlook, and more - Medical News Today - February 6th, 2021
- Stem Cell Study Illuminates the Cause of a Devastating Inherited Heart Disorder - Newswise - February 4th, 2021
- iSpecimen expands offerings to support regenerative medicine, adding cryopreserved stem and immune cells to existing biospecimens available through... - February 4th, 2021
- CU Researchers Win Prize from National Eye Institute - CU Anschutz Today - February 4th, 2021
- Leading Urologist Doubles Down on CaverStem Regenerative Stem Cell Procedure for Treatment of Erectile Dysfunction in Men - BioSpace - January 25th, 2021
- Research Assistant - Department of Obstetrics and Gynaecology job with NATIONAL UNIVERSITY OF SINGAPORE | 239606 - Times Higher Education (THE) - December 24th, 2020
- Getting to the root of why hair goes gray - messenger-inquirer - December 24th, 2020
- How the COVID Virus Induces Inflammation, Cytokine Storm and Stress in Infected Lung Cells - SciTechDaily - December 24th, 2020
- Medicine by Design symposium highlights importance of convergence in regenerative medicine and human health - News@UofT - December 22nd, 2020
- 2020 in Neuroscience, Longevity, and AIand What's to Come - Singularity Hub - December 22nd, 2020
- Updated Findings Show Continued Efficacy for CAR T-Cell Therapy in Heavily Pretreated Myeloma - Targeted Oncology - December 14th, 2020
- Cell Isolation/ Separation Market worth $15.0 billion by 2025 - Exclusive Report by MarketsandMarkets - PRNewswire - December 14th, 2020
- Cord blood banks sell parents on promising stem cell research, but with no guarantees - The Arizona Republic - December 8th, 2020
- Procyon Technologies LLC and Novo Nordisk A/S to Collaborate on the Development of a Stem-Cell Based Therapy for Type 1 Diabetes - PRNewswire - December 8th, 2020
- Genetic engineering transformed stem cells into working mini-livers that extended the life of mice with liver disease - The Conversation US - December 8th, 2020