Hypoimmunogenic derivatives of induced pluripotent stem …

Gyongyosi, M. et al. Meta-analysis of cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data. Circ. Res. 116, 13461360 (2015).

Fisher, S. A., Doree, C., Mathur, A. & Martin-Rendon, E. Meta-analysis of cell therapy trials for patients with heart failure. Circ. Res. 116, 13611377 (2015).

Kandala, J. et al. Meta-analysis of stem cell therapy in chronic ischemic cardiomyopathy. Am. J. Cardiol. 112, 217225 (2013).

Fernandez-Aviles, F. et al. Global position paper on cardiovascular regenerative medicine. Eur. Heart J. 38, 25322546 (2017).

Lipsitz, Y. Y., Timmins, N. E. & Zandstra, P. W. Quality cell therapy manufacturing by design. Nat. Biotechnol. 34, 393400 (2016).

Blair, N. F. & Barker, R. A. Making it personal: the prospects for autologous pluripotent stem cell-derived therapies. Regen. Med. 11, 423425 (2016).

Chakradhar, S. An eye to the future: researchers debate best path for stem cell-derived therapies. Nat. Med. 22, 116119 (2016).

Smith, D. M. Assessing commercial opportunities for autologous and allogeneic cell-based products. Regen. Med. 7, 721732 (2012).

Lipsitz, Y. Y., Bedford, P., Davies, A. H., Timmins, N. E. & Zandstra, P. W. Achieving efficient manufacturing and quality assurance through synthetic cell therapy design. Cell. Stem. Cell. 20, 1317 (2017).

van Berlo, J. H. & Molkentin, J. D. An emerging consensus on cardiac regeneration. Nat. Med. 20, 13861393 (2014).

Arck, P. C. & Hecher, K. Fetomaternal immune cross-talk and its consequences for maternal and offsprings health. Nat. Med. 19, 548556 (2013).

Jaiswal, S. et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 138, 271285 (2009).

Diecke, S. et al. Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency. Sci. Rep. 5, 8081 (2015).

Chang, C. H., Fontes, J. D., Peterlin, M. & Flavell, R. A. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J. Exp. Med. 180, 13671374 (1994).

Elsner, L. et al. The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands. J. Immunol. 179, 55235533 (2007).

Maddaluno, M. et al. Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules. Biomed. Res. Int. 2014, 949845 (2014).

Didie, M., Galla, S., Muppala, V., Dressel, R. & Zimmermann, W. H. Immunological properties of murine parthenogenetic stem cell-derived cardiomyocytes and engineered heart muscle. Front. Immunol. 8, 955 (2017).

Wunderlich, M. et al. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3. Leukemia 24, 17851788 (2010).

Shultz, L. D., Ishikawa, F. & Greiner, D. L. Humanized mice in translational biomedical research. Nat. Rev. Immunol. 7, 118130 (2007).

Billerbeck, E. et al. Development of human CD4+ FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rgamma(null) humanized mice. Blood 117, 30763086 (2011).

Melkus, M. W. et al. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat. Med. 12, 13161322 (2006).

Deuse, T. et al. Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival. Circulation 124, S3S9 (2011).

Wang, D., Quan, Y., Yan, Q., Morales, J. E. & Wetsel, R. A. Targeted disruption of the beta2-microglobulin gene minimizes the immunogenicity of human embryonic stem cells. Stem Cells Transl. Med. 4, 12341245 (2015).

Dressel, R. et al. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB J. 24, 21642177 (2010).

Kruse, V. et al. Human induced pluripotent stem cells are targets for allogeneic and autologous natural killer (NK) cells and killing is partly mediated by the activating NK Receptor DNAM-1. PLoS ONE 10, e0125544 (2015).

Gornalusse, G. G. et al. HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat. Biotechnol. 35, 765772 (2017).

Zhao, L., Teklemariam, T. & Hantash, B. M. Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives. Stem Cell Res. 13, 342354 (2014).

Hou, S., Doherty, P. C., Zijlstra, M., Jaenisch, R. & Katz, J. M. Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells. J. Immunol. 149, 13191325 (1992).

Shiba, Y. et al. Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts. Nature 538, 388391 (2016).

Kawamura, T. et al. Cardiomyocytes derived from MHC-homozygous induced pluripotent stem cells exhibit reduced allogeneic immunogenicity in MHC-matched non-human primates. Stem Cell Rep. 6, 312320 (2016).

Read more here:
Hypoimmunogenic derivatives of induced pluripotent stem ...

Related Posts