Category Archives: Stem Cell Doctors

Stem Cell Worx – Empowering Consumers and Health Professionals

Stem Cell Worx has experienced increased sales of 30% in the last quarter, largely due to its aggressive expansion within the health sector.

The sublingual delivery of the Stem Cell Worx Intraoral Spray is rapid and extremely effective, enabling up to 95% of its natural, pure ingredients to be absorbed quickly into the body, whereas pills and capsules only provide a 10% to 20% absorption rate. This dietary supplement targets advanced immune response, cellular repair and renewal. These fundamentals are the core essence to life and good health and provide the platform for many cumulative health benefits.

(PRWEB) September 26, 2012

The sublingual delivery of the Stem Cell Worx Intraoral Spray is rapid and extremely effective, enabling up to 95% of its natural, pure ingredients to be absorbed quickly into the body, whereas pills and capsules only provide a 10% to 20% absorption rate. This dietary supplement targets advanced immune response, cellular repair and renewal. These fundamentals are the core essence to life and good health and provide the platform for many cumulative health benefits.

Director of Stem Cell Worx, Maree Day reports: This natural health supplement has proved to be a great fit for Healthcare Professionals, especially those who are at the forefront of regenerative medicine. Doctors and Pharmacists recognize the quality and efficacy of the supplement, and the validation from their patients and clients speaks volumes.

No prescription is necessary.

So many health supplements havent kept pace with the latest nutritional and scientific advancements. Stem Cell Worx Intraoral Spray has. It is one of the few innovative health supplements that aligns with todays new science.

Dr. Steven E. Sampson D.O. of The Orthobiologic Institute and Orthohealing Center, 10780 Santa Monica Blvd, Los Angeles reports:

We have integrated Stem Cell Worx into our standard pre and post injection protocol for regenerative injections like platelet rich plasma. Overall, we are seeing enhanced recoveries and facilitation of pain relief more rapid than in the past. Stem Cell Worx is one additional tool to naturally regulate inflammation by positively influencing the immune system. The opportunity to increase granulocyte stimulating factor naturally to boost our bodies own repair system is a perfect marriage with biologic based therapies like PRP. Six weeks following injections, most patients elect to continue taking Stem Cell Worx noting that their immune system is stronger with increased energy and improved quality of sleep.

Dr. Kenneth J. Welker, M.D. of Oregon Optimal Health, 1200 Executive Parkway, Eugene, Oregon reports:

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Stem Cell Worx – Empowering Consumers and Health Professionals

Stem Cells To Aid In Heart-Related Research

June 21, 2012

Connie K. Ho for redOrbit.com

Pumping vigorously night and day, the heart is clearly one of the most important organs in the human body. It is also one of the most delicate parts of the body. As such, news regarding heart-related diseases is beneficial to both doctors and patients. University of Michigan (UM) researchers recently reported the discovery of a new method that could produce cardiac muscle patches from stem cells.

The innovative process was created at UMs Center for Arrhythmia Research and effectively uses stem cells that can copy the hearts squeezing action. The cells showed activity that was like that of peoples resting heart rate. The rhythmic electrical impulse transmission of the engineered cells worked at a rate of 60 beats per minute and this rate was 10 times quicker than rates reported in other stem cell studies.

To date, the majority of studies using induced pluripotent stem cell-derived cardiac muscle cells have focused on single cell functional analysis, remarked senior author Dr. Todd J. Herron, an assistant research professor in the Departments of Internal Medicine and Molecular & Integrative Physiology at the U-M, in a prepared statement.

The researchers believe that the stem biology findings will be beneficial to those who suffer from common but life-threatening heart diseases. They hope that the use of stem cells will assist patients diagnosed with arrhythmia, which is found in approximately 2.5 million people. With arrhythmia, patients suffer an irregularity in the hearts electrical impulses and this can hinder the hearts ability to circulate blood.

For potential stem cell-based cardiac regeneration therapies for heart disease, however, it is critical to develop multi-cellular tissue like constructs that beat as a single unit, commented Herron in the statement.

Regarding the specifics of the project, the goal of the scientists was to use stem cells to develop skin biopsies. These biopsies could be used to produce large quantities of cardiac muscle cells, which could then help transmit uniform electrical impulses and work as a cohesive unit. In collaborating with researchers from the University of Oxford, Imperial College, and the University of Wisconsin, the team was able to design a fluorescent imaging platform. The platform used light emitting diode (LED) illumination to quantify the cells electrical activity.

Action potential and calcium wave impulse propagation trigger each normal heart beat, so it is imperative to record each parameter in bioengineered human cardiac patches, remarked Herron in the statement.

Overall, authors of the study believe that the velocity of the engineered cardiac cells is still slower than the velocity of cells found in the beating adult heart. However, the velocity of the engineered cardiac cells is quicker than those previously reported; it is also similar to the rate found in commonly used rodent cells. For future scientific research purposes, the investigators theorize that human cardiac patches could be utilized instead of rodent systems. The new method could be used in many cardiac research laboratories and allow cardiac stem cell patches to be utilized in disease research, new drug treatment testing, and therapies focused on repairing damaged heart muscles.

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Stem Cells To Aid In Heart-Related Research

Lab-grown vein transplant is new milestone in stem cell research

In a first, doctors in Sweden have transplanted into the body of 10-year-old girl a vein grown in the laboratory from her own stem cells.

The core team that performed the procedure was led by Dr Suchitra Holgersson, a transplant medicine specialist originally from Mumbai, and included four other doctors from India. The landmark transplant was published in the British medical journal The Lancet on Thursday.

The procedure could offer a potential new way for patients lacking healthy veins to undergo dialysis or heart bypass surgery without the problems of synthetic grafts or the need for lifelong immunosuppressive drugs, The Lancet said.

The child had a blockage in her extrahepatic portal vein, which was obstructing blood supply to her liver. Options available to doctors included a liver transplant or taking a vein graft from the umbilical cord of a donor, which would have led to permanent dependence on immunosuppressants.

A third alternative was to graft another vein usually from the leg or neck on to the liver vein. But this procedure is associated with risks of lower limb disorders, and was not considered a viable option due to the girls young age.

Speaking to The Indian Express by phone, Dr Holgersson, a professor in the department of transplant and regenerative medicine at Sahlgrenska Science Park in Gothenburg University, explained the breakthrough procedure:

We took a 9-centimetre graft from a deceased donor and removed all its original cells, leaving a hollow piece of vein. We then extracted stem cells of two kinds from the bone marrow endothelial and smooth muscle cells of the little girl, gave it necessary growth factors, and let it incubate for two weeks.

... contd.

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Lab-grown vein transplant is new milestone in stem cell research

10-year-old girl gets new vein made from her own stem cells in medical first

(CBS News) A 10-year-old girl made medical history when a vein created from her own stem cells was transplanted into her body to treat a life-threatening blockage.

PICTURES: First lab-grown windpipe saves cancer patient

The girl had a condition called hepatic portal vein obstruction in which there is a blockage in the vein that drains blood from the intestines and spleen to the liver. A blockage here can lead to major complications like bleeding, developmental delays, an enlarged spleen and even death. Typical treatments include removing veins from other parts of the body - such as the leg - and transplanting them elsewhere to restore blood flow, but the procedures can be risky and have had mixed success.

For the new procedure, the girl was admitted to the Sahlgrenska University Hospital in Gothenburg, Sweden, where a team had already taken a 9 centimeter segment of vein from the groin of a deceased donor. The doctors stripped all cells from the vein, leaving just a tube of scaffolding, which was then injected with stem cells obtained from the girl's own bone marrow. After two weeks in a bioreactor, the graft was re-implanted in the 10-year-old girl, and her condition has been improving ever since.

The medical milestone is described in the June 14 issue of the The Lancet.

"The young girl in this report was spared the trauma of having veins harvested from the deep neck or leg with the associated risk of lower limb disorders," and avoided the need for a liver transplant, explained Dr. Martin Birchall, chair of laryngology, and Dr. George Hamilton, professor of vascular surgery, both at the University College London, U.K., in a commentary published in the same issue.

The girl had no complications from the operation and her blood flow was restored immediately.

In the year since the procedure, the girl has grown from about 4 feet 4.5 inches to almost 4 feet 7 inches and her weight increased from 66 pounds to 77 pounds. However over that year her blood flow decreased and the graft narrowed, requiring a second stem cell-based procedure. She has remained well since the second procedure, taking long walks of up to two miles and participating in light gymnastics. Especially noteworthy is her immune system has not attempted to fight off the donor tissue, despite her not taking any immunosuppressive drugs which often carry side effects.

"The new stem-cells derived graft resulted not only in good blood flow rates and normal laboratory test values but also, in strikingly improved quality of life for the patient," wrote the surgeons, led by Dr. Michael Olausson, a profsesory of surgery at the University of Gothenburg in Sweden. They added that their work opens up the possibility of trying to reproduce arteries for surgical use, such as for coronary bypass surgery.

This isn't the first procedure to use a patient's stem cells to create new tissue to save a person's life. HealthPop reported in 2011 of an Eritrean man with late-stage throat cancer who received the world's first synthetic windpipe. The organ was grown from the man's stem cells and then applied to a plastic scaffold, eliminating the need for a donor organ.

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10-year-old girl gets new vein made from her own stem cells in medical first

Lab-grown vein transplant marks another milestone in stem cell research

In a first, doctors in Sweden have transplanted into the body of 10-year-old girl a vein grown in the laboratory from her own stem cells.

The core team that performed the procedure was led by Dr Suchitra Holgersson, a transplant medicine scholar originally from Mumbai, and included four other doctors from India. The landmark transplant was published in the British medical journal The Lancet on Thursday.

The child had a blockage in her extrahepatic portal vein, which was obstructing blood supply to her liver. Options available to doctors included a liver transplant or taking a vein graft from the umbilical cord of a donor, which would have led to lifelong dependence on immunosuppressants.

A third alternative was to graft another vein usually from the leg or neck onto the liver vein. This is associated with risks of lower limb disorders, and was not considered a viable option due to the girls young age.

Speaking to The Indian Express by telephone, Dr Holgersson, a professor in the department of transplant and regenerative medicine at Sahlgrenska Science Park in Gothenburg University, said: We took a 9-centimetre graft from a deceased donor and removed all its original cells, leaving a hollow piece of vein. We then extracted stem cells of two kinds from the bone marrow of the little girl endothelial and smooth muscle cells gave it necessary growth factors, and let it incubate for two weeks.

This manufactured vessel was then transplanted into the girl. Blood flow to the liver started immediately after the procedure, and since the stem cells were the patients own, there was no fear of an adverse immune reaction either, and she needs no drugs, Dr Holgersson said.

... contd.

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Lab-grown vein transplant marks another milestone in stem cell research

Doctors Use Stem Cells To Grow Vein For Young Patient

June 14, 2012

Brett Smith for redOrbit.com

A successful transplant operation in Sweden points to a medical future where your doctor can grow a transplant organ from your own cells, making organ donation a thing of the past.

Doctors have now successfully transplanted a vein grown with a patients own stem cells without complications or the need for immunosuppressants, according to a report published this week in The Lancet. The patient was a 10-year-old girl in Sweden who was suffering from a potentially fatal blockage in the vein which drains blood from the intestines and spleen to the liver.

Last March, a team of doctors at the University of Gothenburg decided to grow the new blood vessel used to bypass the blocked vein instead of using an invasive neck or leg surgery to extract one of her own.

The young girl in this report was spared the trauma of having veins harvested from the deep neck or leg with the associated risk of lower limb disorders, and avoided the need for a liver or multivisceral transplantation, Martin Birchall and George Hamilton of University College London wrote in The Lancet.

To start the procedure, doctors took a three-inch section of a cadaver groin vein and stripped it of all living cells, leaving only an inert protein structure. The team then injected it with blood-forming stem cells taken from the girls bone marrow. After growing the vein for two weeks in an incubator, the stem cells had multiplied and converted into vein wall cells, to create a biologically-engineered replacement. The new vein was then implanted into the patient a year ago.

The new stem-cells derived graft resulted not only in good blood flow rates and normal laboratory test values but also, in strikingly improved quality of life for the patient, the report said.

In noting the success of the transplant, the doctors reported that the patient grew 2 inches and gained 11 pounds over the following year. In addition, her parents said that she was more physically active, had improved articulated speech, and had concentrated better on her studies.

The only major complication was the slight constriction of the vein nine months after the operation, which was corrected in a follow-up procedure. During the course of following up on the operation, scientists found no antibodies for the donor vein in the girls blood. This meant her body was not rejecting the transplant because it was recognized as being made of her own cells.

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Doctors Use Stem Cells To Grow Vein For Young Patient

Doctors look to cure HIV patients with cord blood units

Timothy Brown made medical history when he became the first patient who was essentially cured of HIV, after receiving a stem cell transplant from a person who was genetically resistant to the infection. Now, doctors are hoping to build on Browns success by treating HIV patients using cord blood units that have the same HIV-resistant gene.

Brown, 46, was a student living in Berlin in 1995 when he tested positive for HIV. He responded well to therapies for the disease until 2006, when doctors also diagnosed him with acute myeloid leukemia.

The doctor who treated Brown, Dr. Gero Htter from Berlins University Hospital, proposed to tackle his leukemia by using chemotherapy to wipe out his immune system, and then rebuild the immune system with a bone marrow transplant.

However, when searching for an appropriate match, Htter kept his eyes out for a specific donor: one who carried a genetic mutation called delta 32, which disables the CCR5 receptor on immune system cells. The CCR5 receptor is the one HIV uses to infect its victims meaning people who carry the mutation are essentially immune to the disease. Approximately one percent of Europeans carry the mutation, but it is rarer people of African, Asian, or South American descent.

Out of 232 potential donors, Htter found a match for Brown, who also carried the delta 32 mutation, on the 67th try. The doctors performed the transplant, repopulating Browns bone marrow cells with the donor cells. Months later, Brown was in remission for leukemia and had no trace of HIV in his body.

And while Browns leukemia eventually recurred a year later, necessitating another transplant, his HIV never did.

I still have some disabilities due to the treatments its not perfect, Brown told FoxNews.com, explaining that he suffered from speech and balance issues following the procedure. But it is my life, and Im very happy not to have to worry about HIV anymore.

However, Browns stem cell transplant isnt feasible as a widespread treatment for HIV patients, according to doctors. It can be highly difficult to find a matching bone marrow donor let alone one who also carries the HIV-resistant gene.

The cord blood idea came about later because of the success with my transplant, Brown said. In my case, using stem cells, they had to find a perfect match for me. With cord blood, you dont have to use donors that are an exact match, so it means doctors are more likely to find a donor who will work.

Dr. Lawrence Petz, a stem cell transplantation specialist, as well as chief medical officer for StemCyte and president of the Cord Blood Forum, explained cord blood essentially gives doctors more leeway in regards to matching patients with donors and opens the possibility of treating many more people.

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Doctors look to cure HIV patients with cord blood units

NCAA baseball: Mike Kent of Clemson’s biggest save came away from the diamond

CLEMSON, S.C. The cells Mike Kents own cells, the donated stem cells now coursing through his stricken brothers body are working just fine. Thats what they tell him. His family and the doctors are careful to shield Mike, just 21 years old, from most of the bad news regarding Matts battle with Hodgkins lymphoma and lately there has been plenty of it. But they always make sure to tell him: Your cells are doing great.

It can mess with your head, being a stem-cell donor to your own brother. If something goes wrong, it is only natural to wonder if it was your fault. Were your cells bad? And Mike Kent, a 2009 Washington Post All-Met selection at West Springfield High, has enough on his plate right now not just Matts three-year fight with cancer, but also his own baseball career at Clemson to be saddled with all that guilt. Clemson opens play in the NCAA regionals at Columbia, S.C., on Friday.

(Family photo) - Mike Kent, right, poses with his brother, Matt, when Mike was a high school senior and a pitcher for the West Springfield, Va, baseball team.

Because now, Matts liver is failing, the veins breaking down from the high doses of chemotherapy and radiation. He floats in and out of consciousness in the intensive-care unit at the University of Maryland Medical Center in Baltimore, unaware of his surroundings.

Ill be honest: Ive asked them, Is he going to survive this? said Susan Kent, Matt and Mikes mother, a look of sheer resolve on her face. Of course, the doctors wont answer.

Such an awkward spot for a mother who had raised two boys on her own. One of them, a college sophomore, is playing out his dream, preparing to pitch in college baseballs national championship tournament, his life spread out before him. The other son, 26 years old and a late-bloomer who was just starting to get his life in order before the diagnosis, is fighting for his life.

How do you handle such a fate? You play up the positives, thats how. You visit Matt in the hospital Matt being the one who taught Mike the game of baseball, in the absence of a father and you tell him, in great detail, about all of Mikes solid outings at Clemson: the scoreless relief appearances, the saves. And you spare him the gory details about the ugly ones the three-run homers, the bases-loaded walks, the losses.

And you give Mike the barest of details about Matts setbacks: There are some complications. Some side effects. But while Mike knows most of the more pertinent information the liver failure, the ICU you emphasize what is important, the thing Mike needs to know: Your cells are doing great.

Throwing extra innings

The injections, the doctors told Mike, would make him feel like he had the flu. The drug, Neupogen, was being given in eight doses, spread over four days to produce and stimulate white blood cells in his body in preparation for the stem cell transplant. One thing he shouldnt try to do, they told him, was play baseball.

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NCAA baseball: Mike Kent of Clemson’s biggest save came away from the diamond

Stem cell therappy to treat a chimp's torn ACL may prove beneficial for humans

Veterinarians hope a new medical procedure can treat a 25-year-old chimpanzee with a torn ACL, or anterior cruciate ligament, at the "Save the Chimps" in Florida.

The procedure involves injecting the chimp with her own stem cells.

"With chimps we don't want to do a lot of surgical work, put hardware in their knee, they tend to pull out that sort of thing," said Veterinarian Linda Gregard, M.D.

Dr. Darrell Nazareth with the Florida Veterinary League has been using stem cells to treat dogs with arthritis for the past two years, but this is his first chimp.

"We're not using embryonic stem cells, we're not taking embryos and taking their stem cells from there. We're just using the patient's own tissue," said Dr. Nazareth.

The technology harnesses the bodies own ability to heal itself and doctors hope it could find wider use in humans.

After injecting two billion stem cells into Angie's knee, doctors will find out in the next two to three weeks if the stem cell therapy treatment was successful.

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Stem cell therappy to treat a chimp's torn ACL may prove beneficial for humans

Stem cell therapy to treat a chimp's torn ACL may prove beneficial for humans

Veterinarians hope a new medical procedure can treat a 25-year-old chimpanzee with a torn ACL, or anterior cruciate ligament, at the "Save the Chimps" in Florida.

The procedure involves injecting the chimp with her own stem cells.

"With chimps we don't want to do a lot of surgical work, put hardware in their knee, they tend to pull out that sort of thing," said Veterinarian Linda Gregard, M.D.

Dr. Darrell Nazareth with the Florida Veterinary League has been using stem cells to treat dogs with arthritis for the past two years, but this is his first chimp.

"We're not using embryonic stem cells, we're not taking embryos and taking their stem cells from there. We're just using the patient's own tissue," said Dr. Nazareth.

The technology harnesses the bodies own ability to heal itself and doctors hope it could find wider use in humans.

After injecting two billion stem cells into Angie's knee, doctors will find out in the next two to three weeks if the stem cell therapy treatment was successful.

Continued here:
Stem cell therapy to treat a chimp's torn ACL may prove beneficial for humans