Archive for the ‘Stem Cell Doctors’ Category

Sports & Regenerative Medicine Specialist, Stem Cell …

Stem Cell Doctors | Posted by admin
Apr 13 2019

Exercise and sports are generally viewed as positive, health-enhancing activities. But, there are many ways to become injured in the process, such as through a fall, collision, overuse, or simply pushing the body too hard. To deal with the resulting pain and mobility limitations, some people resort to an extended period of inactivity, repeated cortisone injections, long-term medication use, or surgery. In any of those scenarios, the recovery process can be long and frustrating especially for an individual who is accustomed to being very active.

As an avid multi-sport athlete himself, Dr. Lox understands the challenges that many active individuals face when traditional treatments prove to be ineffective for addressing a musculoskeletal condition or sports injury, such as arthritis, tendonitis, bursitis, or joint instability, or a meniscal, ACL, or rotator cuff tear. To help his patients recover as quickly and safely as possible, Dr. Lox offers innovative regenerative treatments, personalized to a patients specific needs. These advanced therapies help many people find effective pain relief and recover, while delaying or eliminating the need for more aggressive treatments, such as joint replacement surgery.

If you would like to learn more about regenerative medicine, how a specific procedure is performed, or how stem cells can potentially aid in injury recovery, Dr. Lox would be pleased to talk with you one on one at his office in the Tampa Bay, FL, area or Beverly Hills, CA. Contact Sports & Regenerative Medicine Centers today to schedule a personal consultation with Dr. Lox.

Dennis M. Lox, M.D. has applied his personal interest in sports medicine. As a World Renowned Stem Cell Pioneer. Dr. Lox helps elite athletes improve their functional level so they may return to sports.

Many patients are turning to stem cell therapy as a means of nonsurgical joint pain relief when their mobility and quality of life are severely affected by conditions like osteoarthritis, torn tendons, and injured ligaments.Dennis M. Lox, M.D.specializes in this progressive, innovative treatment that may be able to help you return to an active, fulfilling life.

Stem cell therapyfor joint injuries and osteoarthritis is suited for many individuals, fromprofessional athletes to active seniors. Adult mesenchymal stem cells, not embryonic stem cells, are used in this procedure, which is performed right in the comfort of Dr. Loxs state-of-the-art clinic. The cells are simply extracted from the patients own body (typically from bone marrow or adipose/ fat tissue), processed in our office, and injected directly into the site of injury. Conditions that can be addressed with stem cell treatment include osteoarthritis, degenerative disc disease, knee joint issues (such as meniscus tears), shoulder damage (such as rotator cuff injuries), hip problems (such as labral tears), and tendonitis, among others. For many patients, astem cell procedure in the knee, hip, shoulder, or another area of the body relieves pain, increases mobility, and may be able to delay or eliminate the need for more aggressive treatments like joint replacement surgery.

If you have questions about adult stem cell therapy for joint injuries and arthritis, how the procedure is performed, and how the stem cells work to repair injured joints and tissues, Dr. Lox would be happy to educate you about the entire process.

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Sports & Regenerative Medicine Specialist, Stem Cell ...

Stem Cell Doctors in Delaware, Stem cell injections, Stem …

Stem Cell Doctors | Posted by admin
Apr 13 2019

Stem Cell Doctors in Delaware. Stem cells are a particular sort of cells that have the capacity to repeat and recover themselves inside the human body. Grown-up mesenchymal foundational microorganisms work as a sort of interior repair framework, having the capacity to separate to recharge different cells. These regenerative cells have the one of a kind ability to remain an undifferentiated cell or turn into another sort of cell with a particular capacity inside the human body, for example, bone, ligament, muscle or skin cells. Given their great and extraordinary regenerative nature, fat inferred regenerative cell treatment offers new potential in the treatment of specific signs.

Delaware, USA a small Mid-Atlantic U.S. state, sits on a peninsula marked by dune-backed beaches bordering the Atlantic Ocean, Delaware River and Delaware Bay. In Dover, the capital, First State Heritage Park encompasses 18th-century Colonial landmarks like the Georgian-style Old State House.

Stem cells have the capability to modify into specific cell types. There are two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult cell type.

We offer a complete way to deal with construct their training by teaching people in general in a straightforward way. Our careful screening process insures doctors a high quality treatment for patients suffering from inflammatory and degenerative conditions.

For further information about our systems or doctors Contact us today.

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Stem Cell Doctors in Delaware, Stem cell injections, Stem ...

Meet Our Doctors | National Stem Cell Centers | NY Stem …

Stem Cell Doctors | Posted by admin
Apr 13 2019

He approaches hair transplants with a discerning eye, aiming to restore a natural hairline for a youthful appearance. He uses the latest techniques with finesse and tailors his work to a patients particular facial attributes for the most meaningful and long-lasting results. Trained at prominent institutions including New York-Presbyterian/Columbia University Medical Center, New York-Presbyterian/Weill Cornell, Memorial Sloan Kettering, and graduated in the top 1% of his medical school and was inducted into the Alpha Omega Alpha medical honor society.

Dr. Doshi has lectured on surgical topics both nationally and internationally, published scientific articles and book chapters, and serves as one of only a handful of selected physicians across the country to advise on cases in the field of facial plastic and head & neck surgery for prominent medical groups.

Dr. Doshi is a member of the American Academy of Facial Plastic and Reconstructive Surgery, American Academy of Cosmetic Surgery, American Society for Laser Medicine and Surgery, American Academy of Otolaryngology Head & Neck Surgery, American Medical Association, and Alpha Omega Alpha Medical Honor Society. He is licensed to practice in New York and New Jersey. Dr. Doshi is Board Certified in Head & Neck / Facial Plastic Surgery.

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Meet Our Doctors | National Stem Cell Centers | NY Stem ...

Stem Cell Doctors | Regenerative Medicine | Stem Cell …

Stem Cell Doctors | Posted by admin
Mar 07 2019

What are stem cells?

Stem cells are the bodys raw materials cells from which all other cells with specialized functions are generated.

Stem cell therapy, also known as regenerative medicine, promotes the repair response of diseased or injured stem cells.

Makes use of cells, biomaterials, and molecules to fix structures in the body that do not function properly due to disease or injury.

To promote repair and restore normal function after disease, illness or injury

Dr. Cesar Amescua is a Pain Management Doctor and Regenerative Medicine Specialist.

The Regenerative Medicine program seeks to develop new therapies by either recruiting stem cells within organs to promote repair, or administering new cells and tissue made from stem cells to restore normal function after disease, illness or injury.

The promising field of Regenerative Medicine is working to restore structure and function of damaged tissues and organs. It is also working to create solutions for organs that become permanently damaged.

The goal of Regenerative Medicine is to find a way to cure previously untreatable injuries and diseases.

Dr. Amescua is board-certified in Anesthesiology and Pain Medicine.

Regenerative Medicine its all about helping human cells, tissues, and organs work properly. This branch of medicine focuses on the way cells live and function every day.

So, to better understand regenerative medicine, we need to consider what would happen if a group of cells in your body werent operating at their best. Conceptually, what could we do to fix that problem?

After several promising treatments in Panama using stem cell technology developed by Medistem Panama Inc. at the City of...

Research has pointed strongly toward autologous adipose tissue-derived mesencymal stem cells

Regenerative medicine for central nervous system (CNS) disorders using cell-based therapies represents an exciting area that requires significant preclinical...

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Stem Cell Doctors | Regenerative Medicine | Stem Cell ...

2nd ever HIV patient in remission after stem cell …

Stem Cell Doctors | Posted by admin
Mar 07 2019

2nd ever HIV patient in remission after stem cell transplant: Doctors originally appeared on abcnews.go.com

A man who previously tested positive for HIV has shown no trace of the virus that causes AIDS since receiving a stem cell transplant more than a year ago, doctors say.

The patient, a resident of the United Kingdom who has chosen to remain anonymous, appears to be the second known person to be declared free of HIV since the pandemic began.

The latest case study was published online Tuesday by the scientific journal Nature and will be presented at the Conference on Retroviruses and Opportunistic Infections in Seattle this month.

(MORE: 'Miles to go' in fight against HIV, UN report warns)

Both HIV-positive patients were diagnosed with cancer and received bone-marrow transplants from donors carrying two copies of a rare genetic mutation, known as CCR5-delta 32, that made them resistant to HIV-1, the most widespread and pathogenic strain of the human immunodeficiency viruses.

The first patient, later identified as American Timothy Ray Brown, underwent two such transplants in Berlin in 2007 and 2008 to treat acute myeloid leukemia after chemotherapy and radiation failed, according to the case report published in the New England Journal of Medicine in 2009.

Brown has been cancer-free and in sustained remission from HIV ever since, as far as doctors can tell.

Blood samples are seen here in a stock photo. (STOCK PHOTO/Getty Images)

The second patient received the transplant in London in 2016 after being diagnosed with advanced Hodgkin lymphoma and going through less intensive chemotherapy.

Regular testing confirmed the so-called "London patient" also has been in long-term remission for the past 18 months since discontinuing antiretroviral therapy, according to the case report, which was carried out by researchers at University College London and Imperial College London with teams at the Universities of Cambridge and Oxford.

"By achieving remission in a second patient using a similar approach, we have shown that the Berlin patient was not an anomaly, and that it really was the treatment approaches that eliminated HIV in these two people," said Dr. Ravindra Gupta, lead author of the new study and University College London's Division of Infection and Immunity professor, in a statement.

(MORE: Man jailed for life after deliberately infecting men with HIV)

The researchers cautioned that a stem cell transplant is not appropriate as a standard treatment for HIV due to the toxicity of chemotherapy given before the transplant.

"While it is too early to say with certainty that our patient is now cured of HIV, and doctors will continue to monitor his condition, the apparent success of haematopoietic stem cell transplantation offers hope in the search for a long-awaited cure for HIV/AIDS," said Dr. Eduardo Olavarria, medical director of London's Hammersmith Hospital blood and marrow transplantation unit and Imperial College London haematology professor, in a statement.

PHOTO: Timothy Ray Brown poses for a photograph, March 4, 2019, in Seattle. (Manuel Valdes/AP)

Some 36.9 million people worldwide were living with HIV/AIDS in 2017, and just 59 percent were receiving antiretroviral therapy, which are medicines to suppress the HIV virus.

Acquired immunodeficiency syndrome, or AIDS, is the most advanced stage of HIV infection. Almost one million people died from AIDS-related illnesses around the world in 2017, according to data from the Joint United Nations Program on HIV/AIDS (UNAIDS).

Early diagnosis and prompt treatment of HIV can help prevent progression.

"At the moment, the only way to treat HIV is with medications that suppress the virus, which people need to take for their entire lives, posing a particular challenge in developing countries," Gupta said. "Finding a way to eliminate the virus entirely is an urgent global priority, but is particularly difficult because the virus integrates into the white blood cells of its host."

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2nd ever HIV patient in remission after stem cell ...

Stem Cell Docu Series

Stem Cell Doctors | Posted by admin
Mar 05 2019

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Information on this web site is provided for informational purposes only. The information is a result of years of practice and experience by the author. This information is not intended as a substitute for the advice provided by your physician or other healthcare professional or any information contained on or in any product label or packaging. Do not use the information on this web site for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or homeopathic supplement, or using any treatment for a health problem. If you have or suspect that you have a medical problem, contact your health care provider promptly. Do not disregard professional medical advice or delay in seeking professional advice because of something you have read on this web site. Information provided on this web site and the use of any products or services purchased from our web site by you DOES NOT create a doctor-patient relationship between you and any of the physicians affiliated with our web site. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

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Dr. Neil Riordan, Cell Therapy Expert – Stem Cell Treatment …

Stem Cell Doctors | Posted by admin
Feb 24 2019

Neil Riordan, PA, PhD is one of the early pioneers and experts in applied stem cell research. Dr. Riordan founded publicly traded company Medistem Laboratories (later Medistem Inc.) which was acquired by Intrexon in 2013.

He is the founder and chairman of Medistem Panama, Inc., a leading stem cell laboratory and research facility located in the Technology Park of the prestigious City of Knowledge in Panama City, Panama. Medistem Panama (est. 2007) is at the forefront of research on the effects of adult stem cells on the course of several chronic diseases and conditions. The stem cell laboratory at Medistem Panama is fully licensed by the Ministry of Health of Panama.

Human umbilical cord tissue-derived mesenchymal stem cells (hUCT-MSCs) that were isolated and grown at Medistem Panama to create master cell banks are currently being used in the United States. These cells serve as the starting material for cellular products used in MSC clinical trials for two Duchennes muscular dystrophy patients under US FDAs designation of Investigational New Drug (IND) for single patient compassionate use. (IND 16026 DMD Single Patient) These trials are the first in the United States to use hUCT-MSCs. Translational Biosciences, a fully-owned subsidiary of Medistem Panama is currently conducting phase I/II clinical trials for multiple sclerosis, autism and rheumatoid arthritis.

Dr. Riordan is founder, chairman and chief science officer of the Stem Cell Institute in Panama, which specializes in the treatment of human diseases and conditions with adult stem cells, primarily human umbilical cord tissue-derived mesenchymal stem cells. Established in 2007, Stem Cell Institute is one of the oldest, most well-known and well-respected stem cell therapy clinics in the world.

He is co-founder and chief science officer of the Riordan Medical Institute (RMI). Located in the Dallas-Fort Worth area city of Southlake, Texas, RMI specializes in the treatment of orthopedic conditions with autologous bone marrow-derived stem cells combined with amniotic tissue products developed by Dr. Riordan.

He is also the founder of Aidan Products, which provides health care professionals with quality nutraceuticals. Dr. Riordans team developed the product Stem-Kine, the only nutritional supplement that is clinically proven to increase the amount of circulating stem cells in the body for an extended period of time. Stem-Kine is currently sold in 35 countries.

Dr. Riordan has published more than 70 scientific articles in international peer-reviewed journals. In the stem cell arena, his colleagues and he have published more than 20 articles on multiple sclerosis, spinal cord injury, heart failure, rheumatoid arthritis, Duchenne muscular dystrophy, autism, and Charcot-Marie-Tooth syndrome. In 2007, Dr. Riordans research team was the first to discover and document the existence of mesenchymal-like stem cells in menstrual blood. For this discovery, his team was honored with the Medical Article of the Year Award from Biomed Central. Other notable journals in which Dr. Riordan has published articles include the British Journal of Cancer, Cellular Immunology, Journal of Immunotherapy, and Translational Medicine.

In addition to his scientific journal publications, Dr. Riordan has authored two books about mesenchymal stem cell therapy: Stem Cell Therapy: A Rising Tide: How Stem Cells Are Disrupting Medicine and Transforming Lives and MSC (Mesenchymal Stem Cells): Clinical Evidence Leading Medicines Next Frontier. Dr. Riordan has also written two scientific book chapters on the use of non-controversial stem cells from placenta and umbilical cord.

Dr. Riordan is an established inventor. He is the inventor or co-inventor on more than 25 patent families, including 11 issued patents. His team collaborates with a number of universities and institutions, including National Institutes of Health, Indiana University, University of California, San Diego, University of Utah, University of Western Ontario, and University of Nebraska.

He has made a number of novel discoveries in the field of cancer research since the mid-1990s when he collaborated with his father, Dr. Hugh Riordan, on the effects of high-dose intravenous vitamin C on cancer cells and the tumor microenvironment. This pioneering study on vitamin Cs preferential toxicity to cancer cells notably led to a 1997 patent for the treatment of cancer with vitamin C. In 2010, Dr. Riordan was granted an additional patent for a new cellular vaccine for cancer patients.

Neil Riordan, PA, PhD earned his Bachelor of Science at Wichita State University and graduated summa cum laude. He received his Masters degree at the University of Nebraska Medical Center. Dr. Riordan completed his education by earning a Ph.D. in Health Sciences at Medical University of the Americas.

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Dr. Neil Riordan, Cell Therapy Expert - Stem Cell Treatment ...

Stem Cell Therapy Tulsa OK | Broken Arrow | Jenks

Stem Cell Doctors | Posted by admin
Feb 24 2019

Stem Cell Therapy in Tulsa, Oklahoma Our physicians utilize stem cell therapy in treating Stem Cell Injections for Arthritis, Tendonitis, Knee Pain & More

As an alternative to surgery, our patients can now benefit from injections of platelet rich plasma, amniotic, bone marrow or adipose stem cells to treat chronic orthopaedic conditions. These treatments can reduce pain and provide long lasting relief from chronic tendinitis, early arthritis and cartilage damage in the joint.

Our surgeons offer these fairly new treatment options; PRP, amniotic membrane stem cell, bone marrow stem cell as well as adipose stem cell injections to successfully treat patients with knee, hip or shoulder osteoarthritis, rotator cuff tendonitis, Achilles tendonitis, chronic bursitis, meniscal tears and degenerative arthritis. (For clarification, amniotic stem cells comes from the amniotic sac not an embryo. While some people may have ethical issues with embryonic stem cell therapy, most people agree the use of amniotic tissue productraises no ethical or moral questions.)

Why do I have chronic pain in my joints and tendons?

As we age, our bodies undergo wear and tear from previous injuries, exercising, playing sports or arthritis. We do not repair these injures as well as we did when we were young. We produce less of our repair cells (mesenchymal stem cells) as we get older so it takes longer to recover.

How can Amniotic tissue injections help me?

Stem cell treatment takes advantage of the bodys ability to repair itself. With amniotic tissue product, the physician injects cells from amniotic tissues into your body. These stem cells have anti-inflammatory properties, similar to steroid and cortisone shots. Whats great is stem cell therapy can go beyond the benefits of standard injection therapy. Stem cells can actually restore degenerated tissue while providing pain relief. The growth factors in amniotic stem cells may replace damaged cells in your body. Stem cell injections also contain hyaluronic acid which lubricates tendons and joints which eases pain and helps to restore mobility.

How are Bone Marrow stem cells obtained?

One of the richest sources of stem cells is bone marrow, and the hip (pelvis) is one of the best and most convenient locations for obtaining bone marrow. During the harvesting procedure, the doctor removes (or aspirates) your cells from the pelvis. A trained nurse or technician then uses specifically designed equipment to concentrate the stem cells in the bone marrow and provides the cells back to the surgeon for implantation at the site of injury. This technique can be performed in one of our procedure rooms at the clinic.

How are Adipose stem cells obtained?

A small sample of Adipose tissue (fat) is removed from above the Superior Iliac spine (love handles) or abdomen under a local anesthetic. Then a trained nurse or technician uses specifically designed equipment to concentrate the adipose stem cells and provides the cells back to the surgeon for implantation at the site of injury. This technique can be performed in one of our procedure rooms at the clinic.

What are the benefits of Stem Cell injections?

Amniotic Stem Cell injections provide patients with a non-surgical treatment option to reduce various types of musculoskeletal pain. The injections are performed under Ultrasound guidance to ensure proper placement of the stem cells. With amniotic stem cells, there is no threat of patient rejection and amniotic fluid is highly concentrated source of stem cells, which makes this type of stem cell injection preferable.

Are Stem Cell injections safe?

Yes, more than 10,000 injections have been performed without a single reported adverse side effect. The use of amniotic stem cells is well researched, safe and effective, plus they have been used by ophthalmologists and plastic surgeons for around 20 years.

Is PRP the same as Stem Cell Therapy?

No, PRP is the injection or addition of blood platelets to enhance or jump-start the healing of soft tissue. Stem cell therapy is the process of using stem cells to create new cells to promote damaged or lost cells. They are different treatments but fall in the category of regenerative medicine.

How is PRP obtained?

To develop a PRP preparation, blood must first be drawn from a patient. The platelets are separated from other blood cells and their concentration is increased during a process called centrifugation. The increased concentration of platelets is then injected back into the region of the body being treated. This technique can also be performed in one of our clinic procedure rooms.

Does insurance cover these regenerative procedures?

While PRP and stem cell therapy has been used for years to treat a multitude of injuries, their application is fairly new to orthopaedics. Due to this, some insurance companies may deny coverage making these procedures self-pay. In most cases its close to the amount of your deductible if you did in fact have a surgery. Our business office will be happy to work with you to obtain alternative payment arrangements prior to scheduling any procedure.

Am I a candidate for these regenerative treatment options?

If you are suffering from any kind of joint, tendon or ligament pain and most other conservative treatments arent alleviating it then you may be a candidate for amniotic tissue product. However if you have severe degenerative osteoarthritis you may not be eligible. If you believe you are a candidate then please fill out the form to the right to schedule a consultation appointment with one of our surgeons. They will look at your X-rays and examine you to determine if you are a candidate for one of these regenerative treatments.

Post-Procedure Instructions for Joints

Immediately After Your Cell Transplant Procedure: The stem cell injection includes producing a micro injury in the joint. As a result, expect the joint to be sore. This can be everything from minimally sore to very sore. Activity: The goal is to allow the stem cells to attach and then to protect them while they differentiate into cartilage. For this reason, youll be asked to keep the joint as still as possible for 30-60 minutes after the procedure. Do not take a bath for three days, but a shower 12 hours after the procedure is fine. 1st 3rd Day: For the first day, you should limit activity on the joint. If you have post-op soreness this may be easy to do, as you may have a natural limp or antalgic gait (your body does this to reduce pressure on the area to allow healing). If you dont have this, then simply, naturally taking a bit of weight off this area as you walk is a good idea this first day. Avoid all contact sports as well as jogging, running, or sports that involve impact on that joint. 4th Day 2nd Week: You can start to walk normally, no more than 30-60 minutes a day. Avoid all contact sports as well as jogging, running, or sports that involve impact on that joint. Bike riding is fine as are stationary bikes (no up/downs), elliptical machines, and swimming (no breast stroke). 3rd 6th Week: Avoid all contact sports as well as jogging, running, or sports that involve impact on that joint. You can walk as much as you like. Bike riding is fine, as are stationary bikes, elliptical machine, and swimming. Stem Cell Therapy Testimonials

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Stem Cell Therapy Tulsa OK | Broken Arrow | Jenks

Stem Cell FAQ – Massachusetts General Hospital, Boston, MA

Stem Cell Doctors | Posted by admin
Feb 24 2019

Why are doctors and scientists so excited about stem cells?

Stem cells have potential in many different areas of health and medical research.

Adult and embryonic stem cells differ in the type of cells that they can develop into embryonic stem cells can become all cell types of the body (they arepluripotent). Adult stem cells are found in mature tissues (bone marrow, skin, brain, etc.) and give rise to other cell types from their tissue or origin (they are are multipotent). For example, adult blood stem cells give rise to red blood cells, white blood cells and platelets.

Adult stem cells are thought to exist in every type of tissue in the body. But, to date, the isolation of many types of adult stem cells has been limited. Hematopoietic (blood) stem cells are readily available via bone marrow aspiration. But stem cells for solid organs such as liver or brain have proven more difficult to identify and derive. The hope is that hESCs can be used to derive every type of adult stem cell in the body and allow research that is currently not possible.

Embryonic stem cells are isolated from 3 to 5 day old human embryos at the blastocyst stage. The blastocyst is a hollow microscopic cluster of several hundred undifferentiated cells.

This is a culture of hESCs derived from a single embryo. Because stem cells can self-replicate, just a few hESCs can give rise to a whole population of identical hESCs, or a cell line.

Once established, a cell line can be grown in the laboratory indefinitely and cells may be frozen for later use or distributed to other researchers. Because each cell line has its own distinct genetic footprint, researchers are often interested in using the same cell line for a number of related experiments.

No. At this point, the promise is huge, but hESC research is still in its early stages. Human embryonic stem cell (hESC) research only began in 1998, when a group led by Dr. James Thomson at the University of Wisconsin developed a technique to isolate and grow the cells.

In late January 2009, the California-based company Geron received FDA clearance to begin the first human clinical trial of cells derived from human embryonic stem cells.

In contrast, research with adult stem cells such as blood-forming stem cells in bone marrow (called hematopoietic stem cells, or HSCs) has been active for over decades. And this research has resulted in treatment of patients; for example, bone marrow (stem cell) transplants have been conducted for over 40 years.

In addition, studies with a limited number of patients have demonstrated the clinical potential of adult stem cells in the treatment of other human diseases that include diabetes and advanced kidney cancer.

Induced pluripotent stem cells (iPS cells) are cells that began as normal adult cells (for example, a skin cell) and were engineered (induced) by scientists to become pluripotent, that is, able to form all cell types of the body. This process is often called 'reprogramming.' While iPS cells and embryonic stem cells share many characteristics they are not identical. Scientists are currently exploring whether they differ in clinically significant ways.

The technology used to generate iPS cells holds great promise for creating patient- and disease-specific cell lines for research purposes. These cells are already useful tools for drug development and scientists hope to use them in transplantation medicine. However, additional research is needed before the reprogramming techniques can be used to generate stem cells suitable for safe and effective therapies.

Somatic cell nuclear transfer (SCNT), is a technique in which the nucleus of a somatic cell (any cell of the body except sperm and egg cells) is injected, or transplanted, into an egg, that has had its nucleus removed. The product of SCNT has the same genetic material as the somatic cell donor.

Yes. SCNT is a technique of cloning. The product of SCNT is nearly genetically identical to the somatic cell used in the process. (Of note, the product of SCNT is not technically 100% identical in that the cytoplasm of the oocyte includes mitochondrial DNA.) While SCNT is considered cloning, it is important to differentiate between therapeutic and reproductive cloning. The following FAQ addresses these differences.

Reproductive cloning includes the placement of the product of SCNT into a uterus for the purpose of a live birth. The resulting organism would, in theory, be the genetic copy of the somatic cell donor. Reproductive cloning has been performed in animals for many years and is burdened by many technical and biological problems. Only about 1 percent of all the eggs that receive donor DNA can develop into normal surviving clones. Therapeutic cloning uses SCNT for the sole purpose of deriving cells for research, and potentially in the future for therapy. In therapeutic cloning, the product of SCNT is not placed into a uterus and hence a live birth is never a possibility. Therapeutic cloning provides two potential benefits.

Yes. Massachusetts state law that was enacted in May 2005 allows hESC research and it allows the derivation of hESCs from embryos that were created for reproductive purposes and are no longer needed for reproduction and from somatic cell nuclear transfer.

The National Academy of Sciences (NAS) issued guidelines for hESC research in April 2005, and subsequently updated those guidelines in 2007 and 2008. The current guidelines contain detailed recommendations with regard to many aspects of hESC research, including:

No. IRB approval is required for:

Until recently, the federal government limited its funding to specific hESCs derived before August 9, 2001. Specifically, federal funds were only allowed for research on hESCs listed on the National Institutes of Health (NIH) Registry, and on derivative products from hESCs on the NIH Registry. On March 9, 2009, President Obama signed an executive order clearing the way for the NIH and other federal agencies to fund research using all kinds of hESCs.

Human embryonic stem cell research at the Center for Regenerative Medicine has been supportedin partby private philanthropic donations. These donations allowed us to support a wide range of research activities that could not have been supported from other sources such as NIH funding. In the future, we expect to receive support for eligible activities from NIH and other funding agencies.

The Center for Regenerative Medicine depends upon philanthropic support. To find out how you can help accelerate research and discovery, please click here.

The Center for Regenerative Medicine is dedicated to understanding how tissues are formed and may be repaired in settings of injury. Embedded at Mass General Hospital, the Center's primary goal is to develop novel therapies to regenerate damaged tissues and thereby overcome debilitating chronic disease. The success of this effort requires a cohesive team of scientists and clinicians with diverse areas of expertise, but with a shared mission and dedication to the larger goal.

The Center for Regenerative Medicine has extensive interactions with other investigators at MGH and in the broader Harvard-MIT community. The Center helped galvanize the establishment of the Harvard Stem Cell Institute (HSCI), which is co-directed by Dr. Scadden and Dr. Douglas Melton of Harvard's Department of Stem Cell and Regenerative Biology and the Howard Hughes Medical Institute. As an important confederated partner of HSCI, the Center brings specific features that augment other elements of HSCI, including unique stem cell clinical investigation expertise and ongoing collaborative clinical trials using stem cell transplantation. The Center emphasizes technologies that will ultimately be critical for the success of stem cell based medicine, including bioengineering, biomaterials expertise, close links to in vivo imaging capability and its GMP facility for sophisticated cell manipulation.

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Stem Cell FAQ - Massachusetts General Hospital, Boston, MA

Stem Cell Knee Therapy Cost | Stem Cell Knee Injection …

Stem Cell Doctors | Posted by admin
Feb 17 2019

Knee pain affects millions of Americans and can become so severe that the pain limits sporting activities, work productivity and daily activities. When a patients ability to live happily is hindered by severe, chronic knee pain, painful knee surgery or knee replacement surgery may be recommended by a physician. A stem cell knee injection treatment is now available to patients who want to postpone knee surgery. In certain patients, stem cell knee therapy cost is more beneficial than a surgery and rehabilitation program. OPTIMAL Pain & Regenerative Medicines board-certified physicians are leading providers in the Dallas, Arlington and Fort Worth, Texas area in treating knee pain with autologous stem cell therapy techniques.

An autologous stem cell knee injection is a non-invasive knee treatment used to treat chronic pain in patients suffering from ligament injuries, tendon injuries, fractures and degenerative joint disorders, such as osteoarthritis. Autologous stem cells are harvested from a patients own body and have the natural ability to help a damaged area heal. Since the stem cells used for stem cell knee injections are extracted directly from a patients hip area, patients do not experience risk factors like the ones present with the use of highly controversial embryonic stem cells.

A stem cell knee injection requires a sample of bone marrow to be removed from the patients own body. After the bone marrow is harvested, the sample is spun in a special machine called a centrifuge to separate a combination of pluripotent stem cells, platelets and white blood cells. The combination is then injected into the damaged knee area to regenerate and promote healing.

When traditional knee repair options, such as weight loss, pain medication and physical therapy, do not alleviate chronic knee pain, some physicians may recommend a knee surgery or knee replacement surgery. Surgery is not always a viable option for all patients. In these cases, a stem cell knee injection may prove to be a beneficial treatment option.

Some patients may be concerned about stem cell knee therapy cost and effectiveness. The physicians at OPTIMAL Pain & Regenerative Medicine are highly trained and experienced at stem cell knee injections. Patients do not need to worry about getting a treatment that is not needed or beneficial to his/hers healing process.

Our physicians follow a strict protocol to ensure a patient is a good candidate and will benefit from the autologous stem cell injection therapy. These protocols include:

When these protocols are followed, stem cell knee injections are highly effective in many patients. The postponement of a painful knee surgery and long rehabilitation process is often a key benefit of autologous stem cell therapy and offsets stem cell knee therapy cost.

For more resources on stem cell knee injections, or stem cell knee therapy cost, please contact OPTIMAL Pain & Regenerative Medicine, located in the Dallas, Arlington and Fort Worth, Texas area.

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Stem Cell Knee Therapy Cost | Stem Cell Knee Injection ...