Our company has built a platform to produce high-quality cells    and tissues for regenerative medicine. That pursuit involves    multiple disciplines, which means everyone here is an expert in    a different language. Some of us are fluent in stem-cell    biology, others in optical engineering, others in machine    learning. When we started the company it wasnt possible to do    biology and engineering under the same roof. When we finally    moved into a shared space we were able to learn each others    lexicons, and we became more strongly aligned. And now that    were all working separately, the bonds created in that process    have helped us deal with things. We cant discuss technical    details at our desks anymore, but weve learned new ways of    working together. Its important to stay in sync as a team, and    in a covid-19 world thats never felt more true.  
      TIM O'CONNELL    
    Founded Blendoor, a job-search platform that hides candidates    names and photos in the initial stages to reduce unconscious    bias.  
    I started coding at 13, and that has gotten me pretty far in my    career (Stanford, MIT, Microsoft). I once viewed humanities and    social science education as nice-to-haves but not    need-to-haves. It wasnt until I came face to face with the    harsh realities of inequity and the paradox of meritocracy that    I realized that artificial intelligence is far from solving    many of our most challenging problems as a human race (for    example, xenophobia, sexism, racism, homophobia, impostor    syndrome, and unconscious bias).  
    The externalities that influence creativity, adoption, and    scale are often more important than the innovation itself. To    be a successful innovator one has to be really in tune with    whats happening in the world on a global scale (or be really    lucky, or better yet both). Venture capital has shortened the    learning curve for some innovators, but bias has limited access    to venture capital for many. Unconscious bias is like an    odorless gasits imperceptible to most, but pervasive and    deadly.   
    To optimize the innovation ecosystem, institutions must invest    more in leveling the playing field. Today and for much of the    documented past, innovation has been reserved for the children    of middle- and upper-class parents. (Research the founders of    companies valued at over $1 billion.) We laud the proverb    Necessity is the mother of invention, but the people who grow    up needing the most, independent of their intelligence, are    often left out of the innovation game. As with all games, the    best players emerge when the barriers to entry are low, the    rules/standards are equally enforced, and there is high    transparency across the board.  
    Audre Lorde once wrote: The masters tools will never    dismantle the masters house.  
    I am a short, melanin-enriched, queer female on planet Earth.    In some ways its easier to be innovative when youre    invisible, but at some point, you need tools to scale:    capital, team, mentorship. The one thing I know now that I wish    I had known earlier is that my path toward getting the tools I    need looks a lot different from the paths of others. Its not    better nor worsesimply different. The hardest part is carving    it out. Now that I know my path isnt blockedrather, it just    didnt existIm way better equipped to win.  
      COURTESY PHOTO    
    Founded DotLab, which makes diagnostic tests focused on womens    health.  
    About a decade ago I worked at the White House Office of    Science and Technology Policy, whose goal was to speed up the    commercialization of technologies being developed in federally    funded labs. While there I saw that some of the most important    work done by the government involved things the media paid no    attention tofor example, the way it could use investments in    research and development to fuel private--sector    innovation.  
    In 2009, the Obama administration released the Strategy for    American Innovation. The idea behind it was to establish the    critical nature of federal government support for R&D. In    particular it stressed the spillover effects, or the idea    that investments in such research end up being beneficial to    people unrelated to the original investment. Or to put it    another way, R&D investment is a public good. Analyses at    the time suggested that in order to produce economic growth we    should be doubling or quadrupling our R&D investments.    Instead that spending has since been slashed, especially in    basic research.  
    President Obama also launched a Lab to Market Initiative meant    to speed the path to market for technologies stemming from    government--funded research. There were also pilot programs    designed to increase the use of government-funded R&D    facilities by entrepreneurs, create incentives to    commercialization, and improve, among other things, the impact    of the Small Business Innovation Research (SBIR) program.  
    My own company, DotLab, ended up being a beneficiary. We    develop novel molecular diagnostic tests for prevalent yet    underserved diseases affecting womens health. Its notoriously    difficult for this field of early--stage diagnostics to attract    private investment, because of unclear regulatory pathways, low    reimbursement rates, or resistance to change among    physiciansor all of the above. Many promising diagnostic    technologies never make it to patients because its so hard for    these types of companies to get financing. A grant from the    SBIR was critical to our early success. I cant be sure that    wed be here today without it.  
      COURTESY PHOTO    
    Founded Ubiquitous Energy, which makes transparent solar cells    that can be put on windows or device screens.  
    I used to imagine innovators as individuals, as most people    probably dothe genius inventor divining solutions in    a lab or garage. But this picture that people have is not only    wrong; it hinders our ability to innovate effectively.  
    Eight years ago I cofounded Ubiquitous Energy, a company based    on an innovation Id helped to launch from an MIT    laba transparent solar cell that promised new ways of    deploying solar technology, like windows that generate energy    or consumer devices powered by their own displays. I learned    that in the messy, scrappy world of tech startups, the key to    innovation is to make it a team sport.  
    Taking any innovation from the lab to commercial reality    requires engaging with all sorts of people. You need to work    with engineering, R&D, business development, and sales    teams, as well as investors, advisors, and customers. By    thoughtfully designing teams and carefully tending to the    connections among them, you ensure that innovation doesnt    happen in a vacuum. If you isolate the engineering team you    risk creating an innovative technology that doesnt have a    customer. If you listen only to the customer you might conceive    of a product that cant practically be made. Neglect investors    and you can find yourself with a business plan that nobody    wants to fund.  
    Working among people with competing priorities takes more    effort. It means encouraging communication so theyre aware of    each others needs as they generate new ideas. You have to find    a way to invite these ideas in, make it okay for people to    disagree respectfully, and encourage the flow of ideas among    the various groups. You need each person to focus on his or her    task, but not so much that it creates boundaries and kills any    sense of creativity in the group.  
    Ive found that viewing innovation as a team sport instills a    creative culture that makes an organization better. The    innovations that result are far greater than anything that    might have come from any one person operating independently.  
      CHRIS SCIACCA / IBM RESEARCH    
    Founded Somalias first incubator and start-up accelerator; now    at IBM Research.  
    People tend to think innovation can be neatly placed into two    categories: incremental or disruptive. They also assume that    the only category that really matters is the disruptive kind,    where you dramatically transform markets or introduce a novel    product. And yes, disruptive innovations in CRISPR, quantum    computing, or batteries are undoubtedly worth the    headlines.  
    But Ive learned that there is immense value in incremental    innovation. When you improve an existing product to cut costs,    or when you make that product more efficient or user friendly,    thats what pays the bills. And in fact those little    innovations can give you the needed tailwind to go after the    disruptive ideas, which can take years to incubate and bring to    fruition. Never underestimate the importance of incremental    improvements.  
      TIM O'CONNELL    
    Cofounded Imprint Energy, which is developing thin, flexible,    and safe print- able batteries.  
    As a CEO of a startup, you get used to hearing no. You also    face an endless succession of what feel like earth--shattering    crises, like nearly running out of cash, losing a key customer,    discovering a widespread product failureor having to shut down    operations because of a global pandemic. But it turns out that    these disasters can actually be good for you. In fact, Im not    sure you can innovate without them. Heres what all our crises    have taught me.  
    Its good to be uncomfortable. We once had a    key customer request a battery capability that wed never    deployed before. The customer made it clear that if we couldnt    develop this capability theyd be less confident in our    product. We wrestled with the risks, not least of which was the    potential embarrassment if we couldnt meet the customers    needs. We knew wed face many technical problems with no    obvious solutions if we tried to pull it off. Yet we decided to    try to satisfy the customer, even if it wasnt obvious at first    how we could get it done. A few weeks later we delivered    something beyond what the customer had asked for, and weve    since grown this capability into a powerful sales tool and    potential revenue streamnot to mention it strengthened our    relationship with the customer.  
    Short-term failure is good. A few years ago    our company began to scale up our manufacturing output in    response to a customers need. In the process we discovered    aberrations we hadnt seen during smaller-scale production. Our    team dived into failure analysis, and we finally attributed the    problem to a single material within the battery. Wed used this    material for years, but now we needed a replacement. Once we    deployed that change, the battery quality, reliability, and    manufacturability drastically improved.  
    Its okay to be vulnerable. One of my hardest    days as Imprints CEO was the day I found out I was pregnant.    We were in the middle of raising a funding round, we had begun    scaling our manufacturing output, and I had been traveling    nonstop for a year. Until that day, I had assumed that my role    as CEO was to exude strength and confidence. With the mounting    pressure I was harder on myself than I needed to be, and now I    had the added stress of being pregnant. I decided to    acknowledge to my team that I was overwhelmed. They rallied    together and found ways to operate more efficiently and    communicate more effectively, supporting me to focus my time    and leverage on our most pressing goals. This gave me not only    the space to plan for the companys future, but also the    resiliency to prepare for my own new normal: leading while    becoming a first-time mother.  
Read more:
Six tales from the trenches of running a startup - MIT Technology Review