Top Providers of the Alpha Thalassemia Market gives a New Dimension easing Measurement and Quantification – GuruFocus.com

Inclusive study on Alpha Thalassemia Market to Attractive Growth by Strategic Industry Evolutionary Analysis 2029| Segmentation, Future Scope, Development Strategies, Competitive Breakdown, and Regional Forecast. The market is expected to remain prominent in the Asia Pacific, Center East, and Africa, North America, South America, and Europe regions as companies are intensifying business operations and focusing on increasing market share.

Explosive Growth In Alpha Thalassemia Market size in terms of revenue (USD MN) is calculated for the study along with the aspects of the factors affecting the market growth (drivers and restraints). The market for alpha thalassemia has been categorized into various segments, for analysis, on the basis of the type, application area, and region. Detailed analysis of alpha thalassemia market Predicted to grow by 2029 with competitive Analysis identifying the key mutual trends and major players of the market and business guidelines till 2029. This strong growth outlook of the Alpha Thalassemia market has been attributed to the advancements in computing capacity for Alpha Thalassemia-based research and applications.

Furthermore, the report offers an in-depth understanding of alpha thalassemia market-particular drivers, constraints and major micro markets. The report highlights many significant points and trends of the industry which are helpful for our esteemed clients. In this research study, the manufacturing base, productivity, manufacturers, strengths, recent trends, features are identified in detailed.

*******Super Discount!! Grab Maximum up-to 25% off On Our Market Research Reports [Single User | Multi User| Corporate Users] Valid Till 31st December 2019.*******

To get all-inclusive information on forecast analysis of the market, request a Free PDF brochure here: https://market.us/report/alpha-thalassemia-market/request-sample/

[Note: Our Free Complimentary Sample Report Accommodate a Brief Introduction To The Synopsis, TOC, List of Tables and Figures, Competitive Landscape and Geographic Segmentation, Innovation and Future Developments Based on Research Methodology]

About Alpha Thalassemia Industry

As per the findings of a new Market.us report titled,Global Alpha Thalassemia Market By Type (Iron Chelating Drugs, Gene Therapy),By Application (Hospitals, Private clinics) and by Region Global Forecast to 2029.This offers a holistic view of the alpha thalassemia market through systematic segmentation that covers every aspect of the target market. The study provides valued information on key competition trends and the most preferred developmental strategies of leading market brands. The analysis covers alpha thalassemia market and its advancements across different industry verticals as well as regions. It targets estimating the current market size and growth potential of the alpha thalassemia industry across sections such as also application and representatives.

Additionally, the analysis also has a comprehensive review of the crucial players on the alpha thalassemia market together side their company profiles, SWOT analysis, latest advancements, and business plans.

Get a customized report here: https://market.us/report/alpha-thalassemia-market/#inquiry

For the Alpha Thalassemia Market research study, the following years have been considered to estimate the market size:

Historic Year:2012 to 2018

Estimated Year:2019

Forecast Year:2020 to 2029

The Alpha Thalassemia Market report serves as a vital guide in portraying present and forecast industry statistics

-The supply/ demand situation, gross margin view and competitive profile of top Alpha Thalassemia players (Bluebird Bio, Novartis, Kiadis Pharma) are presented.

-The Alpha Thalassemia market breakdown by product, type, application and regions will provide sophisticated and precise analysis. Recent developments in Alpha Thalassemia industry, growth opportunities, constraints are studied completely.

-The revenue estimates of Alpha Thalassemia market based on top industry players, their product type, applications and regions is studied.

-In the next segment, the SWOT analysis of players, cost structures, traders, distributors and dealers are listed.

-The forecast study on Alpha Thalassemia industry will be useful for business plans and growth analysis.

-This document is a helpful source of guidance for anyone interested in investing in the Brazing Materials Sale, Insights industry. We welcome requests for any special requirements or customizations from our clients.

To Get Immediate Access, Invest On Report Here: https://market.us/purchase-report/?report_id=66566

Explore More Trending Research Reports Here:

Endoscopy Baskets Market Growth Potential, Opportunities, Industry Challenges and Risks 2029

Drug Allergy Treatments and Drugs Market (2020-2029) Trends and Top Key Companies Profile | Allergy Therapeutics, HAL Allergy Group and Stallergenes Greer

This content has been distributed via WiredRelease press release distribution service. For press release service enquiry, please reach us at [emailprotected].

WiredRelease

Visit WiredRelease's Website

Excerpt from:
Top Providers of the Alpha Thalassemia Market gives a New Dimension easing Measurement and Quantification - GuruFocus.com

Lip Augmentation Market Recent Trends, In-depth Analysis, Market Size Research Report Forecast up to 2027 | Allergan, Anika Therapeutics, Cytophil -…

Lip augmentation is a type of procedure that aims to increase the fullness of a lip through enlargement using fillers such as hyaluronic acid, fat, or implants. Lip augmentation is a cosmetic procedure that gives filled, plumper lips. Nowadays, injectable dermal filler is the most commonly used method of lip augmentation. There are many dermal fillers that can be injected in your lips and around your mouth. The lip augmentation market is anticipated to grow in the market by rising participation of market players and the development of the medical tourism industry. Whereas increasing awareness about lip augmentation is rising geriatric population, and rising demand for dermal fillers is expected to grow the market in the forecast period. However, side effects cause by lip fillers, and high cost of treatment is restraining the market growth.

Download Exclusive PDF Sample [emailprotected] https://www.reportsweb.com/inquiry&RW00013057619/sample

Top Manufacturers Profiles Operating in this Study:

Allergan Anika Therapeutics Inc. Cytophil, Inc. Galderma Laboratories, L.P. Informa plc. Integra LifeSciences Corporation Korman Laboratories Merz Pharma GmbH & Co.KGaA Suneva Medical, Inc Teoxane

MARKET SCOPE

The Lip Augmentation Market Analysis to 2027 is a specialized and in-depth study of the medical devices industry with a special focus on the global market trend analysis. The report aims to provide an overview of in lip augmentation market with detailed market segmentation by type, lip fillers, distribution channel and geography. The lip augmentation market is expected to witness high growth during the forecast period. The report provides key statistics on the market status of the leading in lip augmentation market players and offers key trends and opportunities in the market.

MARKET SEGMENTATION

The lip augmentation market is segmented on the basis of type, lip fillers, distribution channel. Based on type the market is segmented as temporary lip augmentation and permanent lip augmentation. On the basis of lip fillers the market is categorized as fat injection or lipoinjection, hyaluronic acid fillers, lip collagen injections, platelet-rich plasma (PRP) and others. On the basis of distribution channel the market is categorized as hospital pharmacies, clinics, retail pharmacies, drug stores, online pharmacies and others.

REGIONAL FRAMEWORK

The report provides a detailed overview of the industry including both qualitative and quantitative information. It provides overview and forecast of the in lip augmentation market based on various segments. It also provides market size and forecast estimates from year 2017 to 2027 with respect to five major regions, namely; North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South & Central America. The lip augmentation market by each region is later sub-segmented by respective countries and segments. The report covers analysis and forecast of 18 countries globally along with current trend and opportunities prevailing in the region.

The report analyzes factors affecting lip augmentation market from both demand and supply side and further evaluates market dynamics affecting the market during forecast period i.e., drivers, restraints, opportunities, and future trend. The report also provides exhaustive PEST analysis for all five regions namely; North America, Europe, APAC, MEA and South & Central America after evaluating political, economic, social and technological factors effecting the lip augmentation market in these regions.

Avail [emailprotected] https://www.reportsweb.com/inquiry&RW00013057619/discount

TABLE OF CONTENTS

1. INTRODUCTION1.1. SCOPE OF THE STUDY1.2. PUBLISHER RESEARCH REPORT GUIDANCE1.3. MARKET SEGMENTATION1.3.1 Lip Augmentation Market By Type1.3.2 Lip Augmentation Market By Lip fillers1.3.3 Lip Augmentation Market By Distribution Channel1.3.4 Lip Augmentation Market By Region1.3.4.1 By Country

2. KEY TAKEAWAYS

3. RESEARCH METHODOLOGY

4. LIP AUGMENTATION MARKET LANDSCAPE4.1. OVERVIEW4.2. PEST ANALYSIS4.2.1 North America Pest Analysis4.2.2 Europe Pest Analysis4.2.3 Asia-Pacific Pest Analysis4.2.4 Middle East and Africa Pest Analysis4.2.5 South and Central America Pest Analysis4.3. EXPERT OPINIONS

Continue..

About ReportsWeb:

ReportsWeb.com is a one stop shop of market research reports and solutions to various companies across the globe. We help our clients in their decision support system by helping them choose most relevant and cost effective research reports and solutions from various publishers. We provide best in class customer service and our customer support team is always available to help you on your research queries.

Contact Us:

Call: +1-646-491-9876Email: [emailprotected]

This post was originally published on Market Reports Observer

Read more:
Lip Augmentation Market Recent Trends, In-depth Analysis, Market Size Research Report Forecast up to 2027 | Allergan, Anika Therapeutics, Cytophil -...

ESPN reporter diagnosed with pneumonia, HLH. What is HLH? – Crossroads Today

Edward Aschoff, a college football reporter for ESPN, died Tuesday on his 34th birthday, according to ESPN Edward Aschoff, a college football reporter for ESPN, died Tuesday on his 34th birthday, according to ESPN Related stories

BRISTOL, Conn. - When ESPN reporter Edward Aschoff died, he had been diagnosed with multifocal pneumonia and a rare disease known as HLH, his fiance tweeted.

Aschoff was first admitted to the hospital and diagnosed with pneumonia in many parts of his lungs but was brought back to the emergency room when antibiotic treatment failed and he got worse, Katy Berteau said.

"After many tests - bone marrow and lung biopsies - treatment was started for a presumed diagnosis of HLH," she tweeted. "Within 3 days of being moved into the ICU, he passed."

HLH, hemophagocytic lymphohistiocytosis, is a rare disease that affects the immune system.

She did not provide any further details about the manner of Aschoff's death, which occurred on his 34th birthday.

Other people, including Aschoff himself, expressed surprise about the seriousness of the illness in a young man in apparently good health.

"Anyone ever had multifocal (bilateral) pneumonia in their early 30s as some who never gets sick and has a very good immune system? Asking for two friends ... my lungs," he tweeted on December 5.

More questions have come up about his second diagnosis, HLH. It is unclear if Aschoff had HLH or pneumonia first, if one came from the other, and exactly how he died so quickly.

Here is what we know about the diseases Aschoff's had:

Pneumonia is when air sacs in the lungs fill with fluid or pus. It can be caused by a virus, bacteria or a fungus, causing a fever and respiratory problems.

It can occur in one or both lungs, and multifocal means the pneumonia occurs in multiple places.

Thousands of people die around the world each year of pneumonia, but most healthy people can fight it off, especially with antibiotics and antiviral medications. The people most at risk are the young, elderly, frail or immune-compromised.

HLH is a rare disease that affects the immune system, making certain white blood cells attack other blood cells and enlarging the spleen and liver, according to Johns Hopkins Medicine.

It can be inherited or acquired, Johns Hopkins said. About a quarter of cases are passed down through families, and the rest come from infections, a weakened immune system and cancer.

Symptoms can include coughing, difficulty breathing, fever, headaches, rashes, swollen lymph nodes, jaundice and digestive problems, according to Johns Hopkins.

There is treatment for HLH, and acquired forms may clear when properly treated, Johns Hopkins said. If familial HLH goes untreated, it is usually fatal.

Treatments include chemotherapy, immunotherapy, steroids, antibiotic drugs and antiviral drugs. Stem cell transplants can cure HLH in most cases if drug treatments don't work, Johns Hopkins said.

There is no way to prevent HLH, the medical center said.

Here is the original post:
ESPN reporter diagnosed with pneumonia, HLH. What is HLH? - Crossroads Today

2019: the year gene therapy came of age – Times of India

WASHINGTON: In the summer, a mother in Nashville with a seemingly incurable genetic disorder finally found an end to her suffering - by editing her genome.Victoria Gray's recovery from sickle cell disease, which had caused her painful seizures, came in a year of breakthroughs in one of the hottest areas of medical research - gene therapy.'; var randomNumber = Math.random(); var isIndia = (window.geoinfo && window.geoinfo.CountryCode === 'IN') && (window.location.href.indexOf('outsideindia') === -1 ); console.log(isIndia && randomNumber "I have hoped for a cure since I was about 11," the 34-year-old told AFP in an email.

"Since I received the new cells, I have been able to enjoy more time with my family without worrying about pain or an out-of-the-blue emergency."

Over several weeks, Gray's blood was drawn so doctors could get to the cause of her illness - stem cells from her bone marrow that were making deformed red blood cells.

The stem cells were sent to a Scottish laboratory, where their DNA was modified using Crispr/Cas9 - pronounced "Crisper" -- a new tool informally known as molecular "scissors."

The genetically edited cells were transfused back into Gray's veins and bone marrow. A month later, she was producing normal blood cells.

Medics warn that caution is necessary but, theoretically, she has been cured.

"This is one patient. This is early results. We need to see how it works out in other patients," said her doctor, Haydar Frangoul, at the Sarah Cannon Research Institute in Nashville.

"But these results are really exciting."

In Germany, a 19-year-old woman was treated with a similar method for a different blood disease, beta thalassemia. She had previously needed 16 blood transfusions per year.

Nine months later, she is completely free of that burden.

For decades, the DNA of living organisms such as corn and salmon has been modified.

But Crispr, invented in 2012, made gene editing more widely accessible. It is much simpler than preceding technology, cheaper and easy to use in small labs.

The technique has given new impetus to the perennial debate over the wisdom of humanity manipulating life itself.

"It's all developing very quickly," said French geneticist Emmanuelle Charpentier, one of Crispr's inventors and the cofounder of Crispr Therapeutics, the biotech company conducting the clinical trials involving Gray and the German patient.

Crispr is the latest breakthrough in a year of great strides in gene therapy, a medical adventure started three decades ago, when the first TV telethons were raising money for children with muscular dystrophy.

Scientists practising the technique insert a normal gene into cells containing a defective gene.

It does the work the original could not -- such as making normal red blood cells, in Victoria's case, or making tumor-killing super white blood cells for a cancer patient.

Crispr goes even further: instead of adding a gene, the tool edits the genome itself.

After decades of research and clinical trials on a genetic fix to genetic disorders, 2019 saw a historic milestone: approval to bring to market the first gene therapies for a neuromuscular disease in the US and a blood disease in the European Union.

They join several other gene therapies - bringing the total to eight - approved in recent years to treat certain cancers and an inherited blindness.

Serge Braun, the scientific director of the French Muscular Dystrophy Association, sees 2019 as a turning point that will lead to a medical revolution.

"Twenty-five, 30 years, that's the time it had to take," he told AFP from Paris.

"It took a generation for gene therapy to become a reality. Now, it's only going to go faster."

Just outside Washington, at the National Institutes of Health (NIH), researchers are also celebrating a "breakthrough period."

"We have hit an inflection point," said Carrie Wolinetz, NIH's associate director for science policy.

These therapies are exorbitantly expensive, however, costing up to $2 million - meaning patients face grueling negotiations with their insurance companies.

They also involve a complex regimen of procedures that are only available in wealthy countries.

Gray spent months in hospital getting blood drawn, undergoing chemotherapy, having edited stem cells reintroduced via transfusion - and fighting a general infection.

"You cannot do this in a community hospital close to home," said her doctor.

However, the number of approved gene therapies will increase to about 40 by 2022, according to MIT researchers.

They will mostly target cancers and diseases that affect muscles, the eyes and the nervous system.

Another problem with Crispr is that its relative simplicity has triggered the imaginations of rogue practitioners who don't necessarily share the medical ethics of Western medicine.

Last year in China, scientist He Jiankui triggered an international scandal - and his excommunication from the scientific community - when he used Crispr to create what he called the first gene-edited humans.

The biophysicist said he had altered the DNA of human embryos that became twin girls Lulu and Nana.

His goal was to create a mutation that would prevent the girls from contracting HIV, even though there was no specific reason to put them through the process.

"That technology is not safe," said Kiran Musunuru, a genetics professor at the University of Pennsylvania, explaining that the Crispr "scissors" often cut next to the targeted gene, causing unexpected mutations.

"It's very easy to do if you don't care about the consequences," Musunuru added.

Despite the ethical pitfalls, restraint seems mainly to have prevailed so far.

The community is keeping a close eye on Russia, where biologist Denis Rebrikov has said he wants to use Crispr to help deaf parents have children without the disability.

There is also the temptation to genetically edit entire animal species - malaria-causing mosquitoes in Burkina Faso or mice hosting ticks that carry Lyme disease in the US.

The researchers in charge of those projects are advancing carefully, however, fully aware of the unpredictability of chain reactions on the ecosystem.

Charpentier doesn't believe in the more dystopian scenarios predicted for gene therapy, including American "biohackers" injecting themselves with Crispr technology bought online.

See the original post:
2019: the year gene therapy came of age - Times of India

This Is How Human Head Transplants Could Be Achieved, According To A Neurosurgeon – IFLScience

The idea of transplanting a human head onto another persons body may sound like the stuff of science fiction and thats because it is. But while penning a fictional story about the worlds first cranial exchange, neuroscientist Bruce Mathew came up with an idea that he says could soon become a real-life procedure.

Speaking to The Telegraph, Mathew who was previously the clinical lead for neurosurgery at Hull University Teaching Hospitals NHS Trust explained that a head could be grafted onto another body if the entire spinal cord is transplanted along with it.

Initially our intention was to just brainstorm an idea and it seemed rather silly, but then I realized, it actually isnt. If you transplant the brain and keep the brain and spinal cord together its actually not impossible, he said.

The spinal cord is the most profound thing imaginable. You need to keep the brain connected to the spinal cord. The idea that you cut the spinal cord is utterly ridiculous."

Obviously this is not an easy thing to do, and while recent advances have opened up the possibility of reattaching individual severed nerves, the prospect of connecting an entire spinal column is still some way out of reach.

Yet with surgical technologies improving at a rapid rate, Mathew says it is not entirely unrealistic to think that it will probably happen in the next 10 years.

At the moment, you can connect one or two nerves, but with robotics and artificial intelligence well soon be able to do 200 nerves, he explained.

Of course, there are likely to be many complications with such a procedure, as the recipients body will probably reject such a large amount of donor material. While Mathew hasnt figured out all the solutions in detail, he says that transferring gut bacteria along with the head and spinal cord, and stem cell transplants, may help to ensure that the transplant is accepted.

At present, Mathew has no plans to take his idea any further than the pages of his science fiction novel, although Italian neurosurgeon Sergio Canavero has spent the last few years actively attempting to achieve a human head transplant.

In 2017 he announced that he had successfully transplanted the head of one human corpse onto another, and previously claimed to have grafted a donor head onto a monkey although the animal never regained consciousness and would probably have been paralyzed if it had, as the spinal cord remained unattached.

Despite this, Canavero apparently has a willing human donor, and of course, there are thousands of people (and sometimes just heads) across the world cryonically frozenin the hope medicine and technology of the future will be able to revive them. Perhaps it will happen one day, but we're not quite there yet.

See the original post here:
This Is How Human Head Transplants Could Be Achieved, According To A Neurosurgeon - IFLScience

Finding Joy While Struggling With Infertility Over The Holidays – SheKnows

Last night, my parents hosted Chanukah dinner for my siblings and our significant others. My father declared it the best Chanukkah hes ever had. It was truly joyous. We took down several shots of vodka (we are of Russian Jewish heritage) toasting to good health and a drama-free new year.

Our family hasnt had a holiday season like this in a few years. In January of 2018, I was diagnosed with a rare form of non-hodgkin lymphoma, one that afflicts otherwise perfectly healthy young women. Just a few months after I wrapped up graduate school and my husband wrapped up internal medicine residency, we found ourselves in an emergency room. I had been on a long flight and had experienced a very strange sensation in my chest.

Because I was of child-bearing age and my husband had accompanied me to the ER, the doctors almost instinctively thought I was pregnant. Indeed, I had taken out my IUD six months beforehand. After two years of a difficult start to our marriage, living 300 miles apart, Ben and I were finally starting to think about having a child. We werent trying, but we werent not trying. So while we waited for test results, Ben squeezed my hand and whispered, maybe were pregnant?

Little did we know how far off our hopes would be. Six hours later, after the doctors had ruled out everything else that would be normal for a 29-year-old to walk into the ER complaining about, a CT scan revealed a 6x by 8cm tumor in my chest, snug between my lungs, nestled behind my breastbone in a cavernous spot called the mediastinum.

Truly in the blink of an eye, our lives fell apart. It wasnt until my medically-trained husband reviewed the scan results, emerging to face me with tears in his eyes, that I started to digest the doctors words: I had cancer.

As unfortunate as the diagnosis was, and as badly as I wanted to start treatment, I somehow more badly wanted to preserve the chances of us starting a family, as we had been whispering about at bedtime for many months. I didnt know much about how to handle the aftermath of my diagnosis, but I knew I had to move fast to determine if I had the time to freeze my eggs.

We were fortunate to set up care at Memorial Sloan Kettering, where a fertility advisor arranged for me to see a reproductive endocrinologist the next morning. I negotiated about 2 weeks of treatment delay with my oncologist to let me try to squeeze in a cycle of IVF injections before chemotherapy would ensue. Fortunately, he agreed and my IVF doctor took care of the rest.

Within 10 days, and many syringes and ultrasounds later, my egg retrieval day landed on the eve of the most fertile lunar moon in 150 years (after cancer you start to take this woo-woo stuff more seriously). The lunar moon delivered: I retrieved 39 eggs. We decided to put aside nine eggs (I learned the real truth behind the saying, dont put your eggs in one basket) and we attempted fertilization on the remaining 30 eggs. As IVF math would have it, we ended up storing 13 frozen embryos in a freezer on 72nd and 1st avenue.

Having crushed IVF, I thought (foolishly) that treatment might be a breeze. What neither my oncologist nor my reproductive endocrinologist could have prepared me for was that the first phase of treatment didnt work. Within four months of completing first-line therapy, the tumor had regrown.

Last Chanukah, I was in the middle of trying a different, more intense chemotherapy alongside an experimental immunotherapy. This would be followed by ten days of twice-a-day radiation therapy and then lastly an auto stem-cell transplant that rendered me a bubble girl for a number of months.

Today, I am 31 years-old and I am in medically-induced menopause. But, despite all I have been through, I couldnt be happier. I just had my third clean scan of 2019. This year, not only did I learn how to mountain bike in the Sedona desert and kayak in the Norwegian fjords, I learned how to cry. Like, really cry. Cry from your deepest belly, when life feels unsurmountable with its unfairness. I learned how to be genuinely happy for the good news, because theres too much bad news on this planet. Finally, I learned how to enjoy what you have, even when you cant have other things you may want.

Its unclear if and when well be able to have a family. Though we have a plentiful frozen reservoir of embryos on the Upper East Side, I need about 3-4 additional clean scans before my doctors will even consider letting us attempt to try to get pregnant. Those scans, six months apart, are the end dates to these short-term leases on life I feel am living between.

So, for now, I just focus on each six-month lease and dream up other type of babies that I can nurture in the interim, whether thats precious time with my family, new places to visit or new ventures to attempt. Perhaps, most importantly, Im focusing on nurturing me and giving myself the tender love and care Ive been saving for somebody else.

Follow this link:
Finding Joy While Struggling With Infertility Over The Holidays - SheKnows

The reporter driven to do ‘whatever it takes’ to conquer cancer and return to the press box – The Athletic

CLEVELAND Matt Loede stores an orange paper credential on a shelf in his home office. Even after 25 years, its mostly free of smudges and creases.

It includes Loedes name, his media affiliation and the date of the first Indians game he was assigned to cover: July 21, 1994. In the bottom right corner, team employee Susie Giuliano planted her initials to grant Loede access to the interview room. Dennis Martinez tossed a complete game that night but relinquished the Indians late lead in a 6-5 loss to the White Sox.

The credential reminds Loede of the thousands of hours he has spent milling around the Indians clubhouse and tracking jump shots at Cavaliers shootaround. He has reported on three World Series. He has placed his recorder within inches of LeBron James beard. He has attended countless Browns introductory news conferences in Berea.

Nearly 25 years to the day of his initiation to the media, Loede covered the MLB All-Star Game in...

Read more here:
The reporter driven to do 'whatever it takes' to conquer cancer and return to the press box - The Athletic

A blood cancer diagnosis helped me find true happiness – The Guardian

December 2017, and the Christmas party season is in full flow. Everywhere I look are scenes from some hilariously awful Dickens pastiche: revellers squeezed into warm pubs; joyful chatter spilling out on to the street; the sound of carols and the scent of mulled wine in the air. Its as if I am peering in at it all through frosted glass, wishing my own Christmas could be as carefree.

Instead, I have spent a morning turned on my side on a hospital bed while a nervous-looking young doctor works up a sweat attempting to force a long needle into my hipbone. He needs it to go deep enough that he can suck out some of the marrow inside, but my tough bones are making life difficult for him.

I dont feel so tough. My wife and I spend the next fortnight anxiously waiting for the results. Results that should confirm why my body is behaving in unexpected ways: the unusual infections; the crushing fatigue; the old jeans that suddenly slip off my waist.

Christmas is never a nice time to feel alone. Yet, despite the fact I am surrounded by loved ones, that is how I feel: terrifyingly alone. The emotions of the season get warped and amplified. I attempt to go to one party, see a friend who is going through her own hellish time, and we both sob on each others shoulders for five minutes straight. Everything feels raw and heavy. My little girl is not even 18 months old, and I love her more than anything but I find it hard to even be in the same room as her. Its all too much.

If Christmas has lost its religious meaning, then it hasnt for me. I try praying for the first time in about three decades: Er, yes, it has been a while sorry about that but could you just help me out with this one thing? I promise God and Santa Ill be all sorts of good if things turn out OK.

***

My results arrive on 22 December. There is a wait in a hospital corridor that is still too triggering to think about properly. And then a doctor calls me in, sits me down and tells me that I have a rare blood cancer called essential thrombocythemia, which sounds like some cult artist signed to Warp Records in the 90s (the doctor doesnt say that bit). There is no known cure. But dont worry, he says, its manageable. I just need to take some aspirin and keep an eye on it. You will lead a normal life, he says. My wife tells me my face instantly changed colour, the pallid grey lifting for the first time in weeks.

My little girl throws up all over the seat when we pull out of the drive, and it doesnt even feel slightly annoying

Its a strange gift, receiving blood cancer for Christmas. In some ways I preferred the Mr Frosty slushy-making kit I got when I was eight, and maybe even the Scalextric that never quite played out the way you hoped it would from the adverts. And yet what the doctor is telling me you will lead a normal life feels like the biggest and best present I have ever received. Queueing up to be discharged, I let wave after wave of euphoria run through me and think to myself: This has to be the weirdest cancer diagnosis ever.

A day later, we pack up the car and head off to my parents. My little girl throws up all over the back seat as soon as we pull out of the drive, and it doesnt even feel slightly annoying. We laugh. Life is good. That Christmas, for the first time since I can remember, I am truly happy; just living in the moment. The light seems brighter and more beautiful. I notice dew drops on plants and the smell of fresh air. I hug my wife and daughter even more tightly than usual.

***

All this relief is not to last long. In the first week of 2018, I attend a follow-up appointment and am told that, sorry, they hadnt seen all of the bone marrow samples before. My condition is, in fact, developing into a much more serious disease called myelofibrosis, which needs treatment.

A week on from that, I turn up at the hospital, steeled to start chemotherapy. But there is worse news: a team of specialists have discussed my case and they believe I am at high risk of developing acute myeloid leukaemia, a swift and deadly cancer. They recommend you have a stem cell transplant, says the doctor. I ask when. As soon as possible. If I can find a match on the stem cell donor register, then I will be dosed up with drugs so intense that my entire immune system will be wiped out; then a strangers cells will be fed into me and we will all cross our fingers and hope that my body doesnt reject them. The chance of survival and the disease not returning does not seem to me to be all that much better than 50/50. Even if it all succeeds, the recovery process will be long and gruelling.

I spend the next few weeks in a state of catatonic depression. Or do I? Because I am somehow getting things done: I organise a will, I arrange a sperm bank visit (the transplant, even if successful, will leave me infertile), I cry myself senseless writing a letter to my daughter in case the worst should happen. I also drink all the good bottles of wine I had been saving for special occasions. A bottle of Domaine Dujac Morey Saint-Denis 2012 on a Tuesday night with defrosted Quorn chilli not the pairing Id had in mind, but saving it for the future seems silly.

Through all the gloom I see something with startling clarity. I realise that what Im mourning is not so much my old life before all this started a life of pointless anxieties, petty rivalries and overthinking but rather the carefree, optimistic version of life I had briefly glimpsed over Christmas. And yet no sooner have I understood all this than the chance to enact it has been snatched away. I feel like an old professor who has finally unravelled the mysteries of the universe with his dying breath.

***

Over the next few months, something happens that I still find hard to believe. I am transferred to a new hospital with a more specialist team on the case. There are more blood tests and scans, and another long needle is forced into my hip. And then I get another gift, this one in time for Christmas 2018: my condition is not so serious as I was led to believe. It appears to be a peculiar version of a peculiar cancer caught somewhere between the relatively benign essential thrombocythemia and the more concerning myelofibrosis. But it is stable, at least for now, with no signs to suggest it will progress any time soon.

***

I like to think that this year I have made good on my promise to live like I did during the Christmas of 2017. My outlook has certainly changed. When people ask how, I always say the same thing: that its great to get older. The idea of panicking about a milestone such as my imminent 40th seems so ridiculous now. Instead, just think what a privilege it is to be able to get there.

I am more present for my family these days, and less consumed with things I cant control. I have returned to the volunteering role I thought I didnt have time for; I have got fit; I dont let work define my happiness; I am kinder to myself. I have bought lots more nice wine to replace the nice wine I drank with defrosted Quorn chilli.

Do I still get annoyed by delayed trains, lost keys or the fact my daughter is taking half an hour to put on a pink tutu, the only item of clothing in the house that shell wear? It would be a lie to say no. But the second I think: But youre not quite likely to die any more, the problem disappears. I am, undeniably, a happier person.

I still have a malfunction inside me and I still have to think about it every day. Its hard not to my spleen, inflated with excess blood cells, gently nudges against my ribs like an annoying acquaintance who would hate me to forget that all is not quite right. At some point in the future and not even the best doctors can predict exactly when the disease might whirr into life and start scarring my bone marrow, turning it into a barren wasteland that can no longer produce enough blood to keep me alive. Im hopeful that science will find a fix before that time comes. There are encouraging signs on the horizon. And if not? Well, these days I try not to dwell on the future. I am here, instead, for the present. I am alive. I am alive with the spirit of Christmas.

MPN Voice provides information and emotional support to people diagnosed with a myeloproliferative neoplasm

Go here to see the original:
A blood cancer diagnosis helped me find true happiness - The Guardian

Michael Schumacher health: Doctor reveals truth about Schumi as Lewis Hamilton is catching up fast to break F1 legend’s record – EconoTimes

Michael Schumachers health update is one of the things that his fans are always waiting in the news. This is because, for years, they have been kept in the dark as his family decided not to divulge any information about his condition.

The secrecy about Schumachers health began when he was badly injured during a skiing outing in Switzerland. He suffered from a serious head injury that left him in a coma in December 2013.

Based on the reports, the F1 legend was able to come out of his induced coma after six months while others say it took longer. The point is, the public is really clueless and yet, his family still remained silent about his health.

Shumis doctor breaks his silence

Recently, it seems that the public finally had the chance to know something about Michael Schumachers health condition. As per Express, one of the racing champs doctors has finally spoken up and said something about how Schumis is doing these days.

It was said that Dr. Kean-Francois Payen is the physician who was the first medical practitioner who confirmed in the past that Michael Schumacher has woken up from his coma. And today, he is giving some updates about his health by mentioning about the current and recent treatments he had.

"I still visit him occasionally and talk to the family about any progress I see," the doctor said. "There is a one-to-three year plan for the regeneration period.

Schumis wifes role in his road to recovery

Dr. Payen revealed that Corrina is trying everything and making sure that her husband is getting the best treatments sho he can recover soon. The doctor said that Schumis wife is not giving up and always looking for ways to treat Michael so he can be normal again.

While he wants to share something about Michael Schumacher, the doctor also reminded everyone to respect the familys decision to stay quiet when it comes to his condition. He said that fans have to be patient and just wait for the time when the family is ready to open up and speak.

She immediately knew the severity of the situation and the long road ahead, Payen explained. She sees things very clearly and will do anything to make her husbands condition better.

In any case, the doctor confirmed that Michael Schumacher had a stem-cell therapy and another health professional, Professor Philippe Menasche, mentioned that he recently had a heart and vascular surgery at Paris Georges Pompidou Hospital.

See original here:
Michael Schumacher health: Doctor reveals truth about Schumi as Lewis Hamilton is catching up fast to break F1 legend's record - EconoTimes

Mother and son, together, cope with autism and multiple sclerosis – MLive.com

Jacob Austin depends on his mom, and she depends on him.

April Austin, a 33-year-old Eastern Michigan University student who suffers from blindness and other ailments related to multiple sclerosis, relies on a walking cane, a white cane and often her son to get around.

When she's in pain, 12-year-old Jacob, who is autistic, is there to help with things like carrying groceries up the stairs. Jacob relies on his mom for help with communication, focus, learning and emotional needs.

Hes not mentally capable of doing things in his age range right now, so that keeps me going because I know he depends on me, Austin said. "I need him because he keeps me moving. He gives me a reason to keep moving. I know that he needs me to help him with basic daily tasks like bathing and cutting his hair. No matter how bad I'm feeling, I know that he needs me to do those things, so it pushes me to get up and do those things for him.

Below is a peek inside the day-to-day lives of April and Jacob Austin, in photos.

The mother and son have a co-dependent relationship, Austin said.

"Right now hes going through puberty," she said. "I'm a little worried about that because now were dealing with facial hair and stuff like that, but I say were going to work together and figure it out... Some days, we struggle with regular tasks, like taking a bath and doing his homework, even communicating. I am his voice. I have to think for him and speak for him. Because if I dont do it, I don't think no one else will."

More on the Austins here.

Jenna Kieser | jkieser@mlive.com

April and Jacob practice counting on their fingers on an Uber ride home after grocery shopping together. "We sort of need each other," April said. She is unable to drive due to her blindness and relies rely on ride-sharing services like Uber and Lyft to get around. Her insurance carrier covers the costs of getting to and from doctors appointments, but not other transportation needs.

Jenna Kieser | jkieser@mlive.com

April gives Jacob a haircut at their Belleville home. Because Jacob has autism, it can be hard for him to perform some basic tasks. April does what she can to help Jacob live the most comfortable life he can, including giving him haircuts herself. "It's always just me and him," said April.

Jenna Kieser | jkieser@mlive.com

April receives a treatment to help ease symptoms of multiple sclerosis at St. Joseph Mercy Ann Arbor Hospital. She was diagnosed with multiple sclerosis in 2014. Since being diagnosed, she's endured partial blindness, bladder infections and pain throughout her body. She undergoes treatments to help ease her pain, although it comes with a cost. After the treatments, which she undergoes a few times a year, she's usually sick for days, making it difficult to care for Jacob. The treatments themselves last an entire day. She no longer brings Jacob with her to the appointments, instead having friends help care for him.

Jenna Kieser | jkieser@mlive.com

Jacob covers his face as he walks through a Walmart with April. "He has real bad social anxiety." The mother and son are often subject to strange looks when they venture out in public together. Due to Jacob's autism, he has a tendency to yell out or run around. During one trip to a public pool, a young girl asked Jacob if he was dumb, April said. Jacob stayed by his mom's side the rest of the time they were there. "He's such a sweet person," said April of her son. "When I go to Walmart, when I go to stores, I want to see people like Jacob included and working."

Jenna Kieser | jkieser@mlive.com

Photos of April and Jacob lay out around their home. April is working on a photo album with images of the two giving each other kisses. "I often feel that him and I only exist to each other. I believe our ailments together make us even closer."

Jenna Kieser | jkieser@mlive.com

Jacob sits on April's lap during an appointmentwith a child psychologist. Jacob sees a therapist in their home multiple times a week to help him learn to be more independent. Jacob has learned to cook a few meals for himself and will make himself breakfast some mornings before he goes to school. Jacob learning to be more independent has been a priority for April, who hopes that eventually, on her bad days, Jacob can care for himself and live a more fulfilling life.

Jenna Kieser | jkieser@mlive.com

Jacob looks up at April while grocery shopping with her. On days when her pain is bad, Jacob helps support his mom, carrying groceries for her, and giving her the physical support she needs to climbs stairs.

April fastens a brace on Jacob before he gets on the school bus in the morning. The brace is meant to prevent Jacob from running off the bus. Jacob has a history of attempting to run off. It proved to be a challenge for April, especially in recent years as she began to deal with the chronic pain. To keep Jacob from running out of the house, she had a special lock installed on their front door. She said they haven't had to use the lock for some time, as Jacob has gotten older and more responsible.

Jenna Kieser | jkieser@mlive.com

Jacob gives April a kiss as he gets home from school one afternoon. "I want to work for people in the community who can't speak for themselves," said April. She currently works as a long-term substitute teacher for nearby schools, while simultaneously working toward a bachelor's degree in social work from Eastern Michigan University. With her degree, she hopes to advocate for policies that would protect people like Jacob who can't speak for themselves. She also hopes to one day open an autism residential facility where teens and adolescents can live an independent, high-quality life with the right resources. "With training, with therapies, the right medications and education, our kids can really function and do well in society," April said.

Jenna Kieser | jkieser@mlive.com

April watches over Jacob as he gets ready for bed. "The goal is for him to be independent. Autistic people live and thrive on their own all the time," said April. The pair often rely on each other. April does everything she can to be there for her son as both a mother and a friend, she said, providing him with the resources he needs to succeed.

Jenna Kieser | jkieser@mlive.com

Jacob plays on his tablet in his room by himself. "I don't have a lot of support. That's why I'm trying to push his independence, because I can't take him everywhere."

Jenna Kieser | jkieser@mlive.com

With one hand, April holds onto Jacob, and with the other, her cane as they take an Uber to the grocery store. April doesn't use her cane every day. In fact, she often tries to conceal the pain she is feeling. "(Life) doesn't stop, no matter how much pain you're in," April said.

April leads Jacob toward the bus before school in the early morning. Jacob attends BurgerSchoolfor Students with Autism in Garden City, about a 20-minute drive from their home in Belleville. "It takes a lot of work to get your child the help that they need," April said. When April began looking at programs in which to enroll Jacob to help him, she quickly learned how difficult it can be to get your child the help they need. "I had to really sit down and study and look into stuff. I just about know in every state what resources are available to Autistic children."

Jenna Kieser | jkieser@mlive.com

April often speaks of living in isolation and how challenging it has been for her, often feeling alone. She is planning on starting a support group for mothers with children with disabilities. "I just started reaching out," she said. She spends her time advocating for children with Autism and helping parents learn what resources are available to them. She also likes to collect donations for children in need to help provide them with more clothes or food.

April Austin is hoping to undergo a hematopoietic stem cell transplant and has raised more than $5,000 in an online

to help with the costs. She's seeking the treatment in Mexico, where she estimates the cost at about $54,000, whereas the procedure at Northwestern University in Chicago would come close to $100,000.

She plans to get the treatment at Clinica Ruiz in Puebla.

More:EMU student seeks stem cell treatment in Mexico for debilitating multiple sclerosis

Originally posted here:
Mother and son, together, cope with autism and multiple sclerosis - MLive.com