BrainStorm Cell Therapeutics Announces Ralph Kern MD MHSc to Present at the 7th International Stem Cell Meeting – GlobeNewswire

NEW YORK, Nov. 12, 2019 (GLOBE NEWSWIRE) -- BrainStorm Cell Therapeutics, Inc. (NASDAQ:BCLI), a leading developer of adult stem cell therapies for neurodegenerative diseases, today announced that the Companys Chief Operating and Chief Medical Officer Ralph Kern MD MHSc will present at the 7th International Stem Cell Meeting, which is hosted by the Israel Stem Cell Society. The Conference will be held November 12-13, in Tel Aviv, Israel.

Ralph Kern, MD, MHSc, said: I welcome the opportunity to participate in the 7th International Stem Cell Meeting where I will share the advances BrainStorm has made with NurOwn. It is a privilege to participate and to exchange ideas with many of the international scientific leaders in stem cell research.

About NurOwn

NurOwn (autologous MSC-NTF) cells represent a promising investigational therapeutic approach to targeting disease pathways important in neurodegenerative disorders. MSC-NTF cells are produced from autologous, bone marrow-derived mesenchymal stem cells (MSCs) that have been expanded and differentiated ex vivo. MSCs are converted into MSC-NTF cells by growing them under patented conditions that induce the cells to secrete high levels of neurotrophic factors. Autologous MSC-NTF cells can effectively deliver multiple NTFs and immunomodulatory cytokines directly to the site of damage to elicit a desired biological effect and ultimately slow or stabilize disease progression. BrainStorm has fully enrolled a Phase 3 pivotal trial of autologous MSC-NTF cells for the treatment of amyotrophic lateral sclerosis (ALS). BrainStorm also recently received U.S. FDA acceptance to initiate a Phase 2 open-label multicenter trial in progressive MS and enrollment began in March 2019.

About BrainStorm Cell Therapeutics Inc.

BrainStorm Cell Therapeutics Inc. is a leading developer of innovative autologous adult stem cell therapeutics for debilitating neurodegenerative diseases. The Company holds the rights to clinical development and commercialization of the NurOwn technology platform used to produce autologous MSC-NTF cells through an exclusive, worldwide licensing agreement. Autologous MSC-NTF cells have received Orphan Drug status designation from the U.S. Food and Drug Administration (U.S. FDA) and the European Medicines Agency (EMA) in ALS. BrainStorm has fully enrolled a Phase 3 pivotal trial in ALS (NCT03280056), investigating repeat-administration of autologous MSC-NTF cells at six U.S. sites supported by a grant from the California Institute for Regenerative Medicine (CIRM CLIN2-0989). The pivotal study is intended to support a filing for U.S. FDA approval of autologous MSC-NTF cells in ALS. BrainStorm also recently received U.S. FDA clearance to initiate a Phase 2 open-label multicenter trial in progressive Multiple Sclerosis. The Phase 2 study of autologous MSC-NTF cells in patients with progressive MS (NCT03799718) started enrollment in March 2019. For more information, visit the company's website at http://www.brainstorm-cell.com

Safe-Harbor Statement

Statements in this announcement other than historical data and information, including statements regarding future clinical trial enrollment and data, constitute "forward-looking statements" and involve risks and uncertainties that could causeBrainStorm Cell Therapeutics Inc.'sactual results to differ materially from those stated or implied by such forward-looking statements. Terms and phrases such as "may", "should", "would", "could", "will", "expect", "likely", "believe", "plan", "estimate", "predict", "potential", and similar terms and phrases are intended to identify these forward-looking statements. The potential risks and uncertainties include, without limitation, BrainStorms need to raise additional capital, BrainStorms ability to continue as a going concern, regulatory approval of BrainStorms NurOwn treatment candidate, the success of BrainStorms product development programs and research, regulatory and personnel issues, development of a global market for our services, the ability to secure and maintain research institutions to conduct our clinical trials, the ability to generate significant revenue, the ability of BrainStorms NurOwn treatment candidate to achieve broad acceptance as a treatment option for ALS or other neurodegenerative diseases, BrainStorms ability to manufacture and commercialize the NurOwn treatment candidate, obtaining patents that provide meaningful protection, competition and market developments, BrainStorms ability to protect our intellectual property from infringement by third parties, heath reform legislation, demand for our services, currency exchange rates and product liability claims and litigation,; and other factors detailed in BrainStorm's annual report on Form 10-K and quarterly reports on Form 10-Q available athttp://www.sec.gov. These factors should be considered carefully, and readers should not place undue reliance on BrainStorm's forward-looking statements. The forward-looking statements contained in this press release are based on the beliefs, expectations and opinions of management as of the date of this press release. We do not assume any obligation to update forward-looking statements to reflect actual results or assumptions if circumstances or management's beliefs, expectations or opinions should change, unless otherwise required by law. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements.

CONTACTS

Corporate:Uri YablonkaChief Business OfficerBrainStorm Cell Therapeutics Inc.Phone: 646-666-3188uri@brainstorm-cell.com

Media:Sean LeousWestwicke/ICR PRPhone: +1.646.677.1839sean.leous@icrinc.com

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BrainStorm Cell Therapeutics Announces Ralph Kern MD MHSc to Present at the 7th International Stem Cell Meeting - GlobeNewswire

Learn How You Can Treat Your Pain with Regenerative Medicine! – Patch.com

Have you wondered about new and innovative pain treatment processes that could change your quality of life?

Join us Monday, December 16, 7PM at the Woodbridge Main Library as Manisha Chahal, MD of Edison-Metuchen Orthopaedic Group discusses Regenerative Medicine to Treat Pain. Dr. Chahal will walk us through the promising results of regenerative medicine with a focus on platelet rich plasma and stem cells. She will explain how this process works and the evidence to support this cutting edge science. Dr. Chahal will also describe the best practices to go about and the indications to look out for. She will disclose how to avoid misleading providers and illegitimate products.

About Dr. Manisha Chahal, MD

Dr. Manisha Chahal is a board certified Interventional Pain Management Physician who specializes in minimally invasive procedures for pain.

Dr. Chahal treats the following conditions: headache, lower back pain, joint pain, neck pain, CRPS, postherpetic neuralgia, abdominal wall pain, pelvic pain, coccydynia, and sciatica.

Additionally, Dr. Chahal also performs the following procedures: spinal cord stimulators, regenerative medicine (PRP & stem cell injections), Botox for migraines, cervical epidural steroid injection, lumbar translaminar or transforaminal epidural steroid injections, cervical and lumbar facet rhizotomy, discograms, nerve blocks (ultrasound & C-arm guided), knee genicular blocks & rhizotomy, joint injections, trigger point injections, and qutenza treatment (chemical rhizotomy) for PHN pain.

She received her medical degree from Howard University where she was awarded a Trustee Scholarship for academic achievement. She completed her anesthesia residency training at Beth Israel Deaconess Medical Center (Harvard) in Boston. Dr. Chahal did her Pain Management Fellowship at New York Presbyterian/ Weill Cornell Medical Center in NYC. She is board certified by the American Board of Anesthesiology for both anesthesia and pain medicine.

She treats a wide variety of pain diagnoses and has expertise in many procedures including spinal cord stimulators, transforaminal epidural injections, rhizotomies, ultrasound guided nerve blocks, regenerative treatments and botox.

Dr. Chahal's philosophy is use every pain management option available to help patients ease their pain and "get their life back."

The Woodbridge Main Library is located at 1 George Frederick Plaza in Woodbridge, NJ. If you have any questions or need any further information please contact us at 732-634-4450 or visit our website -www.woodbrigelibrary.org.

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Learn How You Can Treat Your Pain with Regenerative Medicine! - Patch.com

New Drug Benefits Patients With Myeloma Who Are Resistant to All Therapies – Dana-Farber Cancer Institute

Earlier this year, a novel drug became the first agent to receive U.S. Food and Drug Administration (FDA) approval for patients with multiple myeloma who have exhausted all types of currently available therapies, including proteasome inhibitors, immunomodulatory drugs and monoclonal antibodies.

A clinical trial found that 26.2 percent of such patients responded with significant shrinkage of their disease, including complete responses, and a median survival of 8.6 months despite their highly refractory disease.

The drug, selinexor or XPOVIO, developed by Karyopharm Therapeutics of Newton, Massachusetts, is a pill given with low-dose dexamethasone. Its currently being tested in a larger trial in combination with other drugs, such as bortezomib, to determine if it can improve outcome in myeloma.

Its novel mechanism of action and ability to overcome highly resistant disease is striking, says Paul Richardson, MD, clinical program leader and director of clinical research in the Jerome Lipper Multiple Myeloma Center at Dana-Farber, and co-senior author of a report on the study in The New England Journal of Medicine. He and other Dana-Farber investigators were involved in the preclinical and clinical research on selinexor.

The accelerated approval of oral XPOVIOmarks an important advance in the treatment paradigm for patients with relapsed refractory multiple myeloma and in my view the drug is an important addition to our therapeutic armamentarium, says Richardson.

Selinexor is the first in a class ofdrugs that bind to a molecule called exportin 1 and block the transport ofseveral cancer-growth proteins from the cell nucleus to the cytoplasm. The drugalso activates tumor-suppressor proteins in the nucleus, leading to apoptosis,or self-destruction, of the cancer cell.

Selinexor earned accelerated approved by the FDA in July 2019 for patients with relapsed or refractory multiple myeloma who received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody drug.

Patients matching this description are known as triple-class refractory, meaning they did not respond satisfactorily to the three main classes of drugs used to treat myeloma. Survival for these patients is extremely short.

The clinical study report in The New England Journal of Medicine published in August included122 patients who had received a median of seven previous treatment regimensincluding chemotherapy, targeted therapy with bortezomib, carfilzomib,lenalidomide, pomalidomide, and monoclonal antibody (daratumumab). Almost allhad undergone stem cell transplant.

Their median age was 65.2 years and had myeloma for a median of 6.6 years; their disease was rapidly worsening, and they were out of options. These individuals represented the growing population of patients who have exhausted available therapies but want to continue with active therapy, say the researchers.

A partial response or better was seen in 26% of patients, including two complete responses (disappearance of the myeloma protein in their blood) and six very good partial responses, and 39% had a minimal response or better. The median duration of response was 4.4 months, median progression-free survival was 3.7 months, and median overall survival was 8.6 months, though in patients who responded the median survival was 15.6 months. Although there was no control group in the study, as in this setting such an approach is very problematic and lacks equipoise, Richardson says that historically, patients like those in the trial have a survival of only two to three months.

Because the window of time to treat such patients was closing rapidly, says Richardson, they started on a high dose of selinexor, with the researchers anticipating the need to reduce doses if adverse effects occurred. This proved to be the case, with 80% of patients having dose modification or interruption because of adverse events. Fatigue, nausea, and decreased appetite were common and low platelet counts occurred in 73% of patients, anemia in 44% of patients, and 22% had low blood sodium levels.

Richardson says the side effects proved manageable with careful supportive care required in this group of patients who were otherwise very ill and had no other treatment options. He notes the FDA approval was based not only on the results of this study, called STORM, but also on early indications of safety from the phase 3 BOSTON study which was recently completed to enrollment.

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New Drug Benefits Patients With Myeloma Who Are Resistant to All Therapies - Dana-Farber Cancer Institute

Notice of Business Alliance between Promethera Biosciences SA and MEDIPAL HOLDINGS – Business Wire

MONT-SAINT-GUIBERT, Belgium--(BUSINESS WIRE)--Promethera Biosciences SA (Promethera) and MEDIPAL HOLDINGS CORPORATION (MEDIPAL) today announced that they have entered into a business alliance agreement. In conjunction with todays alliance, MEDIPAL has decided to increase its shareholdings in the Promethera Group. Details follows below.

The purpose of this alliancePromethera has been developing its lead liver cell-derived technology (HepaStem) in an area of high medical need, primarily for Non-alcoholic steatohepatitis (NASH), Acute-on-chronic liver failure (ACLF) and urea cycle disorder (UCD). Promethera completed the recruitment of 24 patients in its Phase 2a study in Acute-on-chronic liver failure (ACLF) in July 2019. The 3 months follow-up data were presented on 10th November at the AASLD 2019 conference (70th American Association for the Study of the Liver Diseases). In addition, the Phase 2a clinical study in patients with late stage NASH with worlds first cell therapy was initiated in May 2019. MEDIPAL will support Promethera in the commercialization of its products in Japan through the subscription to a private placement of new shares on March 20th, 2019, with the aim to expand the products it handles in the regenerative medicine field going forward.

The purpose of this alliance is to further deepen the cooperative relationship between the two companies by providing access to MEDIPALs know-how and capabilities in the distribution of cellular medicines at ultra-low temperatures. MEDIPAL will support Promethera's clinical trials and aims to provide a steady supply after its product launch.

With about 430 cases per year, the percent of patients receiving a liver transplant in Japan is significantly lower than in the US, where some 8,000 patients receive a transplant every year. Rescue solutions for Japanese patients with fatal liver diseases are performing poorly too. An even closer partnership with MEDIPAL will support us in setting up clinical trials in Japan that could positively impact and contribute to a solution for this considerable medical need in Japan. Building on this partnership, we will accelerate the clinical development of HepaStem towards a subsequent market launch in Japan, which will be a meaningful new development for Japanese patients suffering from end-stage liver disease, said Dr John Tchelingerian, President and CEO of Promethera. Mastering the entire supply chain is a key requirement for an off-the-shelf allogeneic cell therapy product, and MEDIPALs expertise and capabilities in this sector will be very valuable in this regard.

Prometheras HepaStem program can potentially become the worlds first therapeutic product using liver stem cells for the treatment of severe liver diseases, commented Shuichi Watanabe, Chief Executive Officer of MEDIPAL. Liver disease prevalence is rising in Japan and around the world due to an increase in obesity and other metabolic syndromes. The need to deliver effective treatments such as Prometheras is expected to augment rapidly. MEDIPALs system enables strict temperature management and traceability by using SDDU (Specialty Drug Distribution Unit: a liquid nitrogen-based ultra-low cold chain system for drug distribution) and has an extensive expertise in this field. We are very pleased with this partnership and the opportunity to support the development and the logistics of this innovative product candidate with our capabilities.

About MEDIPAL HOLDINGS CORPORATION

Head office

2-7-15, Yaesu Chuo-ku Tokyo 104-8461 Japan

Representative

Shuichi Watanabe, Representative Director, President and CEO

Business

As a holding company, MEDIPAL controls, administers and supports the operating activities of companies in which it holds shares in the Prescription Pharmaceutical Wholesale Business; the Cosmetics, Daily Necessities and OTC Pharmaceutical Wholesale Business; and the Animal Health Products and Food Processing Raw Materials Wholesale Business, and conducts business development for the MEDIPAL Group.

Website

https://www.medipal.co.jp/english

About Promethera Biosciences S.A.

Head office

Watson & Crick Hill, Rue Granbonpr, 11 B-1435 Mont-Saint-Guibert, Belgium

Representative

John Tchelingerian, PhD, President & CEO

Business

Promethera Biosciences is a global innovator in liver therapeutics whose mission is to bring patients life-saving treatments to reduce the need for liver transplantation. Promethera develops and manufactures allogeneic cell-based medicines for liver diseases by using regenerative medicine technology.

Website

https://www.promethera.com/

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Notice of Business Alliance between Promethera Biosciences SA and MEDIPAL HOLDINGS - Business Wire

Silencing Of MAGI1 Promotes The Proliferation And Inhibits Apoptosis O | OTT – Dove Medical Press

Yongzhi Lu,1 Wei Sun,2 Liang Zhang,3 Junyao Li4

1Department of Oncology, Qingdao Municipal Hospital, Qingdao, Shandong Province 266000, Peoples Republic of China; 2Department of Neurology, Qingdao Third Peoples Hospital, Qingdao, Shandong Province 266000, Peoples Republic of China; 3Department of Critical Care Medicine, Qingdao Eighth Peoples Hospital, Qingdao, Shandong Province 266000, Peoples Republic of China; 4Department of Emergency, Qingdao Municipal Hospital, Qingdao, Shandong Province 266000, Peoples Republic of China

Correspondence: Junyao LiDepartment of Emergency, Qingdao Municipal Hospital, Qingdao, Shandong Province 266000, Peoples Republic of ChinaEmail wmy_188@126.com

Background: Membrane-associated guanylate kinase (MAGUK) with inverted orientation protein 1 (MAGI1) is a novel member of the MAGUK family with a vital role in tumor progression related to invasion and metastasis. However, the function of MAGI1 in glioma is currently unknown. We therefore analyzed the expression of MAGI1 protein in human glioma samples, glioma cell lines and glioma stem cells (GSCs), and explored its effects on glioma cell proliferation and apoptosis.Methods: MAGI1 expression in glioma tissues was examined by Western blotting and real-time polymerase chain reaction and its relationships with clinical pathological features were analyzed. The effects of MAGI1 knockdown on the proliferation of glioma cell lines and GSCs were detected by CCK8 and colony-formation assays, and apoptosis was assessed by flow cytometry. We also investigated the effects of MAGI1 silencing on protein expression levels of epithelial-mesenchymal transition biomarkers, as well as -catenin, cyclin D1, PTEN and phospho-Akt by Western blotting.Results: MAGI1 was significantly downregulated in glioma tissues and its expression was related to cancer progression. Silencing of MAGI1 in both glioma cell lines and GSCs enhanced proliferation and inhibited apoptosis. MAGI1 knockdown also significantly increased the expression levels of N-cadherin, vimentin, -catenin, cyclin D1 and phospho-Akt and reduced the expression of E-cadherin and PTEN.Conclusions: Our results indicated that MAGI1 might play a vital role in glioma progression and may represent a potential therapeutic target for the treatment of glioma.

Keywords: glioma, MAGI1, -catenin, EMT, proliferation, knockdown

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Stem Cell Banking Market 2019: Growth, Trends, Demand, Share, Analysis and Forecast to 2026 – Markets Gazette 24

Stem Cell Banking Marketis expected to reachUSD 5830.41 Million by 2026 fromUSD 1593.9 Million in 2017 during the forecast period. A stem cell bank is a facility, which stores stem cells for future use. Stem cell banking is the process of conserving stem cells at temperatures below the freezing point. These cells used for the treatment of Parkinsons syndrome, cancer, diabetes, heart diseases, and others.

Stem cell banking market is segmented by Type, Banking service, Application, and Geography. Based on service type the sample preservation & storage segment is expected to hold maximum market share during the forecast period due to the increasing adoption of stem cell banking services in key countries, growing numbers of stem cell banks across developing countries, increasing public consciousness about the therapeutic applications of stem cells.

On the basis of application, the personalized banking applications segment is fastest-growing segment owing to increasing adoption of precision medicine across established countries, the growing prevalence of blood & immune system-related disorders amongstnew-borns& children, &growing public worries regarding the clinical abuse of stored stem cell samples.

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North America is expected to hold largest market share during the forecast period. The increasing network of stem cell banking services, ongoing support of stem cell lines for various disease treatment, new technological developments in the field of stem cell collection & preservation techniques, increasing public-private investments for stem cell researches, rising number of stem cell transplantation procedures are pouring the growth of the Stem Cell Banking Market in North America.

Cordlife introduced NICE, a clinically approved non-invasive prenatal test in Indonesia and the Philippines.LifeCodexx AG, a Provider of non-invasive prenatal DNA testing in Europe, declared its partnership with LifeCell International Pvt. Ltd., an Indian mother & baby preventive health care Type, to bring PrenaTesT, qNIPT testing for the first time to India. The qNIPT technology, which detects the presence of foetal trisomy 21 (Down Syndrome) from maternal blood, received CE marking (European Conformity) in December 2016.

Cordlife Group Limited and China Cord Blood Corporation announced that the two companies collaborated in order to support patients across the China, Singapore, Hong Kong, Indonesia, India, the Philippines, and Malaysia to identify suitable cord blood matching units for stem cell therapy.

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Scope of the report Stem Cell Banking Market:

Stem Cell Banking Market by Type:

Umbilical Cord Stem Cell Adult Stem CellEmbryonic Stem Cell Stem Cell Banking Market by Service Type

Storage Analysis Processing Collection & Transportation Stem Cell Banking Market by Application

Cerebral Palsy Thalassemia Cancer Diseases Diabetes Autism Stem Cell Banking Market by region

North America Europe APAC Latin America MEAKey Players Stem Cell Banking Market:

1. CCBC2. CBR Systems, Inc.3. ViaCord4. Esperite5. Vcanbio6. Boyalife7. LifeCell8. Crioestaminal9. RMS Regrow10. Cryo-cell11. Cordlife Group12. PBKM FamiCord13. Cells4life14. Beikebiotech15. StemCyte

MAJOR TOC OF THE REPORT

Chapter One: Stem Cell Banking Market Overview

Chapter Two: Manufacturers Profiles

Chapter Three: Global Stem Cell Banking Market Competition, by Players

Chapter Four: Global Stem Cell Banking Market Size by Regions

Chapter Five: North America Stem Cell Banking Revenue by Countries

Chapter Six: Europe Stem Cell Banking Revenue by Countries

Chapter Seven: Asia-Pacific Stem Cell Banking Revenue by Countries

Chapter Eight: South America Stem Cell Banking Revenue by Countries

Chapter Nine: Middle East and Africa Revenue Stem Cell Banking by Countries

Chapter Ten: Global Stem Cell Banking Market Segment by Type

Chapter Eleven: Global Stem Cell Banking Market Segment by Application

Chapter Twelve: Global Stem Cell Banking Market Size Forecast (2019-2026)

Browse Full Report with Facts and Figures of Stem Cell Banking Market Report at:https://www.maximizemarketresearch.com/market-report/stem-cell-banking-market/13540/

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Stem Cell Banking Market 2019: Growth, Trends, Demand, Share, Analysis and Forecast to 2026 - Markets Gazette 24

4th Annual Bioprocessing of Advanced Cellular Therapies & Regenerative Medicine Congress – Montana Ledger

Date: 10th 11th March 2020 Location: London UK

Regenerative therapies are proving its acceptance in the potential of cell-based therapies for chronic disorders. Since our past three editions, our aim through this conference is to provide an illustrative approach to recent developments in technologies of bioprocessing of cellular therapies, to process development and addressing qualitative and regulatory hurdles.

In the 4th edition of MarketsandMarkets Bioprocessing of Advanced Cellular Therapies & Regenerative Medicine, we would be focusing on the pre-clinical, manufacturing, clinical and regulatory aspects of cell therapies and regenerative medicine. This Congress event will be held on 10th and 11th March 2020 in London -UK

Get Register and Download the Agenda at https://www.reportsnreports.com/events/4th-annual-marketsandmarkets-bioprocessing-of-advanced-cellular-therapies-regenerative-medicine-congress/

Key Pointers 4th Annual MarketsandMarkets Bioprocessing of Advanced Cellular Therapies & Regenerative Medicine Congress

Conference Registration

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4th Annual Bioprocessing of Advanced Cellular Therapies & Regenerative Medicine Congress - Montana Ledger

Global Progenitor Cell-Based Market to Witness Robust Expansion throughout the Forecast 2026 – Herald Correspondent

Global Progenitor Cell-Based Market By Type (Allogeneic Stem Cell, Autologous Stem Cell), Therapeutic Application (Musculoskeletal Disorders, Wound and Injuries, Neurology, Cardiovascular Diseases (CVD), Gastrointestinal Diseases, Surgeries, Others), Cell Source (Adipose Tissue-Derived Mesenchymal Stem Cells, Bone Marrow-Derived Mesenchymal Stem Cells, Embryo/Cord Blood Stem Cells, Others), End User (Laboratory, Hospitals, Research Institute), Geography (North America, Europe, Asia-Pacific, South America, Middle East and Africa) Industry Trends and Forecast to 2026

Global progenitor cell-based market is estimated to register a substantial CAGR in the forecast period of 2019 to 2026. The imminent market report contains data for historic year 2017, the base year of calculation is 2018 and the forecast period is 2019 to 2026. The growth of the market can be attributed to the rising geriatric population.

Progenitor cell are the kind of stem cell which are located in bone marrow and also called as hematopoietic. These cells give rise to the different cell lines. The progenitor cells can divide and stem cells can replicate indefinitely. Progenitor cells are used in various neurological disorders such as Parkinson disease and Huntington disease.

Prevalence of Parkinsons disease (PD) increases with increasing age but an estimated four percent of people with Parkinsons disease are diagnosed before age 50, more than 10 million people worldwide are living with Parkinsons disease, and other neurological diseases.

Market Drivers

Market Restraints

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By Type

By Therapeutic Application

By Cell Source

By End User

By Geography

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Key Developments in the Market:

Competitive Analysis:

Global progenitor cell-based market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of progenitor cell-based market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Key Market Competitors:

Some of the major companies functioning in global progenitor cell-based market are F. Hoffmann-La Roche Ltd, Pfizer Inc., Merck & Co., Inc., Abbott, Vericel, Novartis AG, Alcon, GlaxoSmithKline plc, BAXTER INTERNATIONAL INC, Boehringer Ingelheim International GmbH, Amgen Inc., Bristol-Myers Squibb Company, Nuvasive, Inc., Organogenesis, Inc., Nu-Tech International, MiMedx, Stability Biologic., Takara Bio Inc., Caladrius, Biosciences, Inc., U.S. Stem Cell, Inc., Cesca Therapeutics and Osiris Therapeutics, Inc among others

Data assemblage and base year analysis is done using data collection modules with large sample sizes. The market data is analysed and forecasted using market statistical and coherent models. Also market share analysis and key trend analysis are the major success factors in the market report. To know more pleaserequest an analyst callor can drop down your enquiry.

The key research methodology used byDBMR researchteam is data triangulation which involves data mining, analysis of the impact of data variables on the market, and primary (industry expert) validation. Apart from this, other data models include Vendor Positioning Grid, Market Time Line Analysis, Market Overview and Guide, Company Positioning Grid, Company Market Share Analysis, Standards of Measurement, Top to Bottom Analysis and Vendor Share Analysis. To know more about the research methodology, drop in an inquiry to speak to our industry experts.

Primary Respondents

Demand Side: Doctors, Surgeons, Medical Consultants, Nurses, Hospital Buyers, Group Purchasing Organizations, Associations, Insurers, Medical Payers, Healthcare Authorities, Universities, Technical Writers, Scientists, Promoters, and Investors among others.

Reasons to Purchase this Report

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Global Progenitor Cell-Based Market to Witness Robust Expansion throughout the Forecast 2026 - Herald Correspondent

Business Analytics of Regenerative Medicine Market to See Excellent Growth by 2026 |Popular Keysights: Organogenesis Inc., Vericel Corporation, Osiris…

The Regenerative Medicine Market is anticipated to reach over USD 79.23 billion by 2026 according to a new research published by Alexa Reports Research. In 2017, the cell therapy dominated the global Regenerative Medicine market, in terms of revenue. North America is expected to be the leading contributor to the global market revenue in 2017.

Regenerative medicine is a branch of medicine that regrows, and repairs the damaged cells in the human body. These medicines include the use of stem cells, tissue engineering, that further helps in developing new organ that function smoothly. These medicines have the caliber of developing an entire organ as these cells are multipotent. The cells are majorly isolated from bone marrow, and umbilical cord blood.

Get Sample Report PDF of Regenerative Medicine research report @ https://www.alexareports.com/report-sample/10264

The regenerative medicine market is primarily driven by the increasing number of individuals suffering from cancer, rising need to monitor and treating these chronic diseases in the limited time. Furthermore, stringent government policies, proper reimbursement policies, and increasing government healthcare expenditure for developing healthcare infrastructure to also boost the market growth in coming years. Also, rising number of organ transplantation, and increasing number of products in pipeline that are waiting for approval create major opportunity for the regenerative medicines in the coming years. However, some of the ethical and religious concerns for the use of stem cells, and lack of proper regulatory for the approval of various drugs would impede the market growth during the forecast period.

North America generated the highest revenue in the Regenerative Medicine market in 2017, and is expected to be the leading region globally during the forecast period. Increasing number of patients suffering from chronic diseases, improved healthcare infrastructure and health facilities, accessibility of healthcare facilities, are the primary factors driving the market growth in this region. While, Asia Pacific to be the fastest growing region in the coming years. The growth in this region is majorly attributed to the developing healthcare infrastructure of the countries like India, & China, and rising awareness for the use of regenerative medicines as an effective treatment option for chronic diseases.

The key players operating in the Regenerative Medicine market include Organogenesis Inc., Vericel Corporation, Osiris Therapeutics, Inc., Stryker Corporation, and NuVasive, Inc., Medtronic Plc., Acelity, Cook Biotech Inc., Integra LifeSciences, and C.R. Bard. These companies launch new products and collaborate with other market leaders to innovate and launch new products to meet the increasing needs and requirements of consumers.For Getting [emailprotected] https://www.alexareports.com/check-discount/10264

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Business Analytics of Regenerative Medicine Market to See Excellent Growth by 2026 |Popular Keysights: Organogenesis Inc., Vericel Corporation, Osiris...

Analysis of Regenerative Medicine Market 2019-2024: Industry Trends, Share, Size, Price, Revenue, Business Strategy, Production Technology Forecast to…

The Regenerative Medicine Market research report 2019 delivers comprehensive information about the market ranging from the establishment to the predictable growth trend.Regenerative Medicine market report provides brief analytical data of the market contenders globally using advanced methodological approaches, such as SWOT analysis, production chain, cost, sales margin, financial details, recent developments. Regenerative Medicine market report also offers market competitors that includes detailed company profiles along with company product specifications.

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Key Market Trends:

Dermatology is the Segment by Application that is Expected to be the Largest During the Forecast Period

Dermatology is estimated to have the largest share in revenue generation, and this high contribution is attributive to the presence of easy grafting techniques for dermatological wounds and diseases. Skin, being an organ with great cell replication characteristics, provides various types of stem cells from its different layers. Therefore, there are a broad range of products present, from patches to cure small injuries to matrix and grafts for chronic wounds and burns. Thus, the segment is expected to continue to dominate the market through to the forecast period.

The increasing number of accidents and bone defects is also expected to drive the regenerative medicine market. There are also several research studies that are being conducted on tissue engineering for the development of bone graft substitutes, with the help of regenerative medicine. So, with the new advances in bone graft, the market is expected to grow over the forecast period.

North America Holds the Largest Share and is Expected to Follow the Same Trend Over the Forecast Period

North America is estimated to have the largest share, in terms of revenue, owing to the presence of major players and rapid advances in technology, along with high investments in stem cell and oncology research. There is also an increasing prevalence of diseases, such as cancer and diabetes, which can now be cured by various stem cell therapies. Additionally, the awareness regarding the available stem cell procedures and therapies among people is rising, which in turn, is increasing the demand for the overall market.

The Research Document Will Answer Following Questions Such as:

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Detailed TOC of Regenerative Medicine Market Report 2019-2024:

1 INTRODUCTION1.1 Study Deliverables1.2 Study Assumptions1.3 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS4.1 Market Overview4.2 Market Drivers4.2.1 Increasing Adoption of Stem Cell Technology4.2.2 Technological Advancements in Regenerative Medicine4.3 Market Restraints4.3.1 Regulatory and Ethical Issues4.3.2 High Cost of Treatments4.4 Porters Five Forces Analysis4.4.1 Threat of New Entrants4.4.2 Bargaining Power of Buyers/Consumers4.4.3 Bargaining Power of Suppliers4.4.4 Threat of Substitute Products4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION5.1 By Type of Technology5.1.1 Stem Cell Therapy5.1.2 Biomaterial5.1.3 Tissue Engineering5.1.4 Other Types of Technologies5.2 By Application5.2.1 Bone Graft Substitutes5.2.2 Osteoarticular Diseases5.2.3 Dermatology5.2.4 Cardiovascular5.2.5 Central Nervous System5.2.6 Other Applications5.3 Geography5.3.1 North America5.3.1.1 United States5.3.1.2 Canada5.3.1.3 Mexico5.3.2 Europe5.3.2.1 Germany5.3.2.2 United Kingdom5.3.2.3 France5.3.2.4 Italy5.3.2.5 Spain5.3.2.6 Rest of Europe5.3.3 Asia-Pacific5.3.3.1 China5.3.3.2 Japan5.3.3.3 India5.3.3.4 Australia5.3.3.5 South Korea5.3.3.6 Rest of Asia-Pacific5.3.4 Middle East & Africa5.3.4.1 GCC5.3.4.2 South Africa5.3.4.3 Rest of Middle East & Africa5.3.5 South America5.3.5.1 Brazil5.3.5.2 Argentina5.3.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE6.1 Company Profiles6.1.1 Allergan6.1.2 Osiris Therapeutics6.1.3 Integra Lifesciences6.1.4 Cook Biotech Incorporated6.1.5 Organogenesis Inc.6.1.6 Baxter6.1.7 Medtronic6.1.8 Thermo Fisher Scientific6.1.9 Sigma-Aldrich Co.6.1.10 Becton Dickinson and Company

7 MARKET OPPORTUNITIES AND FUTURE TRENDS

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Analysis of Regenerative Medicine Market 2019-2024: Industry Trends, Share, Size, Price, Revenue, Business Strategy, Production Technology Forecast to...