Creative Medical Technology Holdings Announces Reversion of Liver Failure Using ImmCelz Personalized Cellular Immunotherapy in Preclinical Model -…

PHOENIX, Dec. 29, 2020 /PRNewswire/ --(OTC-CELZ)Creative Medical Technology Holdings Inc. announced today novel data and patent filing No. 63131261 describing the ability of ImmCelz to reverse liver failure in the carbon tetrachloride preclinical model of hepatocyte necrosis.

These findings are the basis for a patent filing covering various means of generating the ImmCelz product in a hepatoprotective specific manner. The Company has previously reported that ImmCelz is capable of treating animal models of stroke,1 as well as inducing "immunological tolerance" in a model of autoimmune rheumatoid arthritis.2

The work is an extension of previously published findings of Dr. Thomas E. Ichim, in which mesenchymal stem cells were capable of inhibiting progression of liver failure.3

"I am proud of the work the team at Creative Medical Technologies is conducting in advancing the concept of immunologically-mediated regeneration,"said Dr. Ichim, Co-inventor of the patent. "ImmCelz is an advancement on our previous liver failure work due to the fact that we have shown transfer of regenerative activity from the stem cell to the immune cell. Immune cells possess ability to home to injured tissues faster than stem cells due to their smaller size. Additionally, immune cells possess immunological memory, which we believe may be applied to the concept of regeneration."

"While stem cell therapeutics are recognized as the future of medicine, I believe it is important to realize that many activities of stem cells are mediated by changes to the immune system," said Dr. Amit Patel, Board Member of the Company and Co-Inventor of the Patent Application. "ImmCelz represents a fundamental advancement in regenerative medicine in that instead of administering stem cells in the body to induce immune modulation, we actually optimize the immune modulation in the laboratory before injecting immune cells into the patient."

Being at the forefront in identifying novel regenerative treatment options, the Company possesses numerous issued patents in the area of cellular therapy, including patent no. 10,842,815 covering use of T regulatory cells for spinal disc regeneration, patent no. 9,598,673 covering stem cell therapy for disc regeneration, patent no. 10,792,310 covering regeneration of ovaries using endothelial progenitor cells and mesenchymal stem cells, patent no. 8,372,797 covering use of stem cells for erectile dysfunction, and patent no. 7,569,385 licensed from the University of California covering a novel stem cell type.

"Liver failure represents a significant unmet medical need and I am extremely excited that ImmCelz has the potential to help the numerous patients on the liver transplant waiting list who currently have no other option.

With growing validation and acceptance of such technologies, the company intends to continue to broaden its intellectual property portfolio by compiling research data and filing patents, in order to record early filing dates and increase the likelihood of our receiving patent issue.

We continue to welcome opportunities with collaborators and Key Opinion Leaders as we are dedicated to accelerating the further development of our technology."

About Creative Medical Technology Holdings

Creative Medical Technology Holdings, Inc. is a commercial stage biotechnology company specializing in stem cell technology in the fields of urology, neurology and orthopedics and trades on the OTC under the ticker symbol CELZ. For further information about the company, please visitwww.creativemedicaltechnology.com.

Forward Looking Statements

OTC Markets has not reviewed and does not accept responsibility for the adequacy or accuracy of this release. This news release may contain forward-looking statements including but not limited to comments regarding the timing and content of upcoming clinical trials and laboratory results, marketing efforts, funding, etc. Forward-looking statements address future events and conditions and, therefore, involve inherent risks and uncertainties. Actual results may differ materially from those currently anticipated in such statements. See the periodic and other reports filed by Creative Medical Technology Holdings, Inc. with the Securities and Exchange Commission and available on the Commission's website atwww.sec.gov.

Creativemedicaltechnology.com http://www.StemSpine.com http://www.Caverstem.com http://www.Femcelz.com

1Creative Medical Technology Holdings Identifies Mechanism of Action of ImmCelz Stroke Regenerative Activity (prnewswire.com) 2Creative Medical Technology Holdings Reports Positive Preclinical Data on ImmCelz Immunotherapy Product in Rheumatoid Arthritis Model | BioSpace 3Human endometrial regenerative cells alleviate carbon tetrachloride-induced acute liver injury in mice | Journal of Translational Medicine | Full Text (biomedcentral.com)

SOURCE Creative Medical Technology Holdings, Inc.

http://creativemedicaltechnology.com

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Creative Medical Technology Holdings Announces Reversion of Liver Failure Using ImmCelz Personalized Cellular Immunotherapy in Preclinical Model -...

Rheumatoid Arthritis Stem Cell Therapy Market Latest Trends and Future Growth Study by 2029 – Farming Sector

Global Rheumatoid Arthritis Stem Cell Therapy Market: Overview

Rheumatoid arthritis is an inflammatory disease of the bodys supportive tissues, usually affecting an individuals toes and fingers. Inflammation is triggered by an abnormal response to the bodys normally functioning tissues. This results in malformed joints and severe pain. Stem cells are novel cells that are generated in regenerative centers of the body. They can be transformed into any other cell type in the body with the right kind of stimulus.

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Stem cell therapy for rheumatoid arthritis works on the principle of such cellular replacement. Stem cells are injected into a patients body and are transformed on site into anti inflammatory cells that limit the spread of this disease. Stem cells work better than traditional inflammation suppressing medicines because they are more organic and act in a targeted manner. In light of the development of innovations in allopathic medicine and demand of people for better healthcare facilities, the market for rheumatoid arthritis stem cell therapy is expected to grow at a commendable pace from 2019 to 2029, opines TMRR.

Global Rheumatoid Arthritis Stem Cell Therapy Market: Competitive Landscape

Handful of pharmaceutical manufacturing facilities is seen to be involved in the production of stem cell therapy solutions.

Significant players n the market include.

Some of these manufacturers are established players in the pharmaceutical industry and have branched into the foray of stem cell therapy. Their established base for pharmaceutical therapy makes the distribution and marketing of stem cell therapy easier. Innovations in this market scenario are funded by these players to increase patient compliance with therapy.

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Global Rheumatoid Arthritis Stem Cell Therapy Market: Key Trends and Drivers

Global Rheumatoid Arthritis Stem Cell Therapy Market: Regional Analysis

North America and Europe currently lead in the rheumatoid arthritis stem cell therapy market. This might be because of the presence of a robust healthcare infrastructure that is under pressure from people for better facilities. Moreover, most innovatory laboratories are based in these regions and enjoy supple funding from regional governments. Population in these regions too is more aged than in other regions of the world. Hence, market growth for stem cell therapy should be good here.

The Asia Pacific region (APAC) is expected to register the fastest growth in this market in the coming years. A growing healthcare infrastructure that derives protocol from western medicine should support the growth of stem cell therapy. Population here is also expected to age in future decades, and an increasingly stressful lifestyle shall undoubtedly bring an increase in incidence of stressful conditions like rheumatoid arthritis.

Based on treatment type, the global rheumatoid arthritis stem cell therapy market can be segmented into:

Based on application, the global rheumatoid arthritis stem cell therapy market can be segmented into:

Based on distribution channel, the global rheumatoid arthritis stem cell therapy market can be segmented into:

Based on geography, the global rheumatoid arthritis stem cell therapy market can be segmented into:

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About TMR Research

TMR Research is a premier provider of customized market research and consulting services to busi-ness entities keen on succeeding in todays supercharged economic climate. Armed with an experi-enced, dedicated, and dynamic team of analysts, we are redefining the way our clients conduct business by providing them with authoritative and trusted research studies in tune with the latest methodologies and market trends.

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Rheumatoid Arthritis Stem Cell Therapy Market Latest Trends and Future Growth Study by 2029 - Farming Sector

Impacts of COVID 19 on Stem Cell Therapy Market 2020 Size, Demand, Opportunities & Forecast To 2026 – Factory Gate

The newly added research report illustrating details on global Stem Cell Therapy market delivers key insights on specific market elements such as competition intensity, regional growth opportunities, vendor profiles and requisite understanding of most potential growth triggers and vendor activities that harbinger growth in global Stem Cell Therapy market. Crucial details on SWOT analysis, PESTEL analysis and Porters Five Forces analytical reviews have been professed with great detail in the report to encourage high investment returns by leading players in global Stem Cell Therapy market. The report carries out a deep analytical study to identify and understand the potential of core factors that stimulate high end growth. The report includes an illustrative overview and serves as an ideal reference point to encourage thoughtful market discretion pertaining to current, historical and future ready business decisions, trends and technologies that have growth steering vigor.

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This report gives a complete comprehension of different viewpoints, for example, monetary, creation in the Stem Cell Therapy market. The report contains the current situation of the market by utilizing the effective and exact chronicled information in different market fragments, for example, type and Application Different contextual analyses from different industry specialists are remembered for the report to shape the organizations.

The Stem Cell Therapy market report gives complete data of the development drivers and restrictions that will characterize the business development in the impending years. In addition, it recognizes the open doors existing across the different areas to additional guide business development.

Segmentation Overview The global Stem Cell Therapy market has been examined with ample detailing to disclose vital market specific developments across segment categories. Segment classification of the market structure has been encouraged by our seasoned in-house research experts to allow readers comprehend the versatility of the market in terms of product and service variation. Additional details on regional expanse and geography-based vendor investments are also discussed extensively based on which global Stem Cell Therapy market is splintered into type, application and end-user.

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Stem Cell Therapy Market Segmentation Type Analysis of Stem Cell Therapy Market:

Based on cell source, the market has been segmented into,

Adipose Tissue-Derived Mesenchymal SCs Bone Marrow-Derived Mesenchymal SCs Embryonic SCs Other Sources

Applications Analysis of Stem Cell Therapy Market:

Based on therapeutic application, the market has been segmented into,

Musculoskeletal Disorders Wounds & Injuries Cardiovascular Diseases Gastrointestinal Diseases Immune System Diseases Other Applications

COVID-19 Impact on Stem Cell Therapy Market: The outbreak of COVID-19 has brought along a global recession, which has impacted several industries. Along with this impact COVID Pandemic has also generated few new business opportunities for Stem Cell Therapy Market. Overall competitive landscape and market dynamics of Stem Cell Therapy has been disrupted due to this pandemic. All these disruptions and impacts has been analysed quantifiably in this report, which is backed by market trends, events and revenue shift analysis. COVID impact analysis also covers strategic adjustments for Tier 1, 2 and 3 players of Stem Cell Therapy Market.

Table of Contents Includes Major Pointes as follows: 1. Stem Cell Therapy Market Overview 2. Global Stem Cell Therapy Market Competition by Manufacturers 3. Global Stem Cell Therapy Capacity, Production, Revenue (Value) by Region (2014-2019) 4. Global Stem Cell Therapy Supply (Production), Consumption, Export, Import by Region (2014-2019) 5. Global Stem Cell Therapy Production, Revenue (Value), Price Trend by Type 6. Global Stem Cell Therapy Market Analysis by Application 7. Global Stem Cell Therapy Manufacturers Profiles/Analysis 8. Stem Cell Therapy Manufacturing Cost Analysis 9. Industrial Chain, Sourcing Strategy and Downstream Buyers 10. Marketing Strategy Analysis, Distributors/Traders 11. Market Effect Factors Analysis 12. Global Stem Cell Therapy Market Forecast (2019-2026) 13. Research Findings and Conclusion 14. Appendix

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Impacts of COVID 19 on Stem Cell Therapy Market 2020 Size, Demand, Opportunities & Forecast To 2026 - Factory Gate

Efficacy and safety of mesenchymal stem cells for the treatment of patients infected with COVID-19: a systematic review and meta-analysis protocol -…

This article was originally published here

BMJ Open. 2020 Dec 18;10(12):e042085. doi: 10.1136/bmjopen-2020-042085.

ABSTRACT

INTRODUCTION: To date, no specific antivirus drugs or vaccines have been available to prevent or treat the COVID-19 pandemic. Mesenchymal stem cell (MSC) therapy may be a promising therapeutic approach that reduces the high mortality in critical cases. This protocol is proposed for a systematic review and meta-analysis that aims to evaluate the efficacy and safety of MSC therapy on patients with COVID-19.

METHODS AND ANALYSIS: Ten databases including PubMed, EMBASE, Cochrane Library, CINAHL, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), Wanfang database, China Biomedical Literature Database (CBM) and Chinese Biomedical Literature Service System (SinoMed) will be searched from inception to 1 December 2020. All published randomised controlled trials, clinical controlled trials and case series that meet the prespecified eligibility criteria will be included. The primary outcomes include mortality, incidence and severity of adverse events, respiratory improvement, days from ventilator, duration of fever, progression rate from mild or moderate to severe, improvement of such serious symptoms as difficulty breathing or shortness of breath, chest pain or pressure, and loss of speech or movement, biomarkers of laboratory examination and changes in CT. The secondary outcomes include dexamethasone doses and quality of life. Two reviewers will independently perform study selection, data extraction and assessment of bias risk. Data synthesis will be conducted using RevMan software (V.5.3.5). If necessary, subgroup and sensitivity analysis will be performed. Grading of Recommendations Assessment, Development and Evaluation system will be used to assess the strength of evidence.

ETHICS AND DISSEMINATION: Ethical approval is not necessary since no individual patient or privacy data have been collected. The results of this review will be disseminated in a peer-reviewed journal or an academic conference presentation.

PROSPERO REGISTRATION NUMBER: CRD42020190079.

PMID:33371042 | DOI:10.1136/bmjopen-2020-042085

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Efficacy and safety of mesenchymal stem cells for the treatment of patients infected with COVID-19: a systematic review and meta-analysis protocol -...

Global Stem Cell Therapy Market Industry 2021 In-depth Market Analysis and Recent Developments, Share, Revenue and Forecast 2025 | Anterogen Co. Inc….

The market study on the global Stem Cell Therapy market published by Adroit Market Research exhibits the important aspects that are estimated to shape the growth of the global Stem Cell Therapy market over the forecast period. The market for Stem Cell Therapy is growing with a significant grow rate and is considered to achieve notable revenue by the end of 2025. In addition to this, the research provides a detailed analysis of the market value & forecast, covering the different segments and geographies.

The latest study indicates that the Global Stem Cell Therapy Market is expected to register a lucrative annual growth rate during the predicted time period. The report also showcases important information related to the assessment that the market retains and an in-depth analysis of the Global Stem Cell Therapy Market along with several growth opportunities. Readers of the report are expected to receive useful guidelines on how to make your companys presence known in the market, thereby increasing its share in the coming years.

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Market dynamics including drivers, restraints, Stem Cell Therapy market challenges, opportunities, influence factors, and trends are especially focused upon to give a clear understanding of the global Stem Cell Therapy market. The research study includes segmental analysis where important type, application, and regional segments are studied in quite some detail. It also includes Stem Cell Therapy market channel, distributor, and customer analysis, manufacturing cost analysis, company profiles, market analysis by application, production, revenue, and price trend analysis by type, production and consumption analysis by region, and various other market studies. Our researchers have used top-of-the-line primary and secondary research techniques to prepare the Stem Cell Therapy report.

The report covers the competitive landscape of the global Stem Cell Therapy market. It states the market state of all the prominent vendors in the market. It is very important for the vendors to provide customers with new and improved product/ services in order to gain their loyalty. The up-to-date, complete product knowledge, end users, industry growth will drive the profitability and revenue. Stem Cell Therapy report studies the current state of the market to analyze the future opportunities and risks. Stem Cell Therapy report provides a 360-degree global market state. Potential consumers, market values, and the future scope for the Stem Cell Therapy market are explained thoroughly to the users in this report. The key players of Stem Cell Therapy industry, their product portfolio, market share, industry profiles is studied in this report.

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Stem Cell Therapy Market Segmentation Type Analysis of Stem Cell Therapy Market:

Based on cell source, the market has been segmented into,

Adipose Tissue-Derived Mesenchymal SCs Bone Marrow-Derived Mesenchymal SCs Embryonic SCs Other Sources

Applications Analysis of Stem Cell Therapy Market:

Based on therapeutic application, the market has been segmented into,

Musculoskeletal Disorders Wounds & Injuries Cardiovascular Diseases Gastrointestinal Diseases Immune System Diseases Other Applications

Regional Description On the basis of region, the market has been segmented into Americas, Europe, Asia Pacific (APAC), and the Middle East and Africa (MEA). Regional segmentation has been provided at a high level and a more detailed level in terms of a country-wise analysis of the market in each region. This regional analysis points out regions with highest consumptions and production rates and also provides a comparative study basis these factors. The revenues generated in these regions, the market growth rate and the compound annual growth rate percentage are also discussed in detail.

Some Points from Table of Content Global Stem Cell Therapy Market Report 2020 by Key Players, Types, Applications, Countries, Market Size, Forecast to 2027 Chapter 1 Report Overview Chapter 2 Global Market Growth Trends Chapter 3 Value Chain of Stem Cell Therapy Market Chapter 4 Players Profiles Chapter 5 Global Stem Cell Therapy Market Analysis by Regions Chapter 6 North America Stem Cell Therapy Market Analysis by Countries Chapter 7 Europe Stem Cell Therapy Market Analysis by Countries Chapter 8 Asia-Pacific Stem Cell Therapy Market Analysis by Countries Chapter 9 Middle East and Africa Stem Cell Therapy Market Analysis by Countries Chapter 10 South America Stem Cell Therapy Market Analysis by Countries Chapter 11 Global Stem Cell Therapy Market Segment by Types Chapter 12 Global Stem Cell Therapy Market Segment by Applications Chapter 13 Stem Cell Therapy Market Forecast by Regions (2020-2027) Chapter 14 Appendix

If you have any questions on this report, please reach out to us @ https://www.adroitmarketresearch.com/contacts/enquiry-before-buying/691?utm_source=Pallavi

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Contact Us :

Ryan Johnson Account Manager Global 3131 McKinney Ave Ste 600, Dallas, TX 75204, U.S.A Phone No.: USA: +1 972-362 -8199 / +91 9665341414

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Global Stem Cell Therapy Market Industry 2021 In-depth Market Analysis and Recent Developments, Share, Revenue and Forecast 2025 | Anterogen Co. Inc....