Posts Tagged ‘retraction’

Disgraced Japan researcher fails to replicate 'game changing' stem cell results

Stem Cell Treatment | Posted by admin
Dec 19 2014

Published December 19, 2014

Haruko Obokata, a researcher at semi-governmental research institute RIKEN, lowers her eyes during a news conference in Osaka, western Japan, in this photo taken by Kyodo April 9, 2014. REUTERS/Kyodo

A disgraced Japanese researcher has failed to replicate results hailed as a potential breakthrough in stem-cell treatment and efforts to do so will be abandoned, officials at her research institute said on Friday.

The scandal involving the research, which detailed simple ways to reprogram mature cells back to an embryonic-like state, eventually led to the retraction of papers published in the influential journal Nature and tarnished the reputation of Japanese scientific research.

The so-called STAP cells had seemed to offer hope for replacing damaged cells or even growing new human organs for sick or injured people, and made research leader Haruko Obokata a national sensation after the news broke in January.

But the discovery began to unravel soon after when other researchers said they could not replicate the results. Investigations by Riken, the Japanese research institute where Obokata was based, found she had plagiarized and fabricated parts of the papers, which were withdrawn in July.

“We were unable to recreate the STAP phenomenon,” said Svinicki Aizawa, head of Aiken’s verification team.

“We had planned to continue replication efforts until March next year, but in the light of these results, we have decided to terminate the experiments.”

But when asked if this decision meant that the STAP cells did not exist, Aizawa said that as a scientist, he could not give an answer.

“All I can say is that we couldn’t replicate the original results,” he added.

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Disgraced Japan researcher fails to replicate 'game changing' stem cell results

New stem cell research retracted

Stem Cell Medical Center | Posted by admin
Jul 05 2014

Almost five months after publication, Nature retracted two papers regarding new stem cell research. This retraction came after various errors were spotted, both in the papers presented and the attempted recreations of the experiments described. The research, which claimed that embryonic stem cells could be created by exposing normal skin cells to stress, appeared to be a medical breakthrough at the time of publication.

The lead author was found guilty of misconduct, while her employer was threatened numerous times with dismantlement, reports Scientific American. It appeared that parts of the methods were plagiarized from previous studies in the stem cell field, and the supposed ‘different’ cells and embryos described in the study were actually the same.

It was only after recreation of the described methods failed that the errors were brought forth and scrutinized by various outside sources, including one of the co-authors. The Riken Center for Developmental Biology in Japan began in-depth investigations into the studies in February 2014, and categorized some of the major errors that skewed the written results as misconduct, reports Uncover California.

Nature released a statement regarding the publication, saying, “The episode has further highlighted flaws in Natures procedures and in the procedures of institutions that publish with us.”

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New stem cell research retracted