Local Doctor Working To ‘Brew Blood’ To Combat Certain Disorders – CBS Boston / WBZ

March 28, 2017 6:44 PM By Dr. Mallika Marshall

BOSTON (CBS) An everyday problem in the medical community is a lack of blood donations which are needed for transfusions worldwide.

Aware of this issue, scientists are working on a procedure that could brew blood to help combat certain blood disorders.

Scientists work on brewing blood to end lack of blood supply. (WBZ-TV)

As a child in Jamaica, Claud DAguilar was diagnosed with sickle cell disease. Its something thats genetic. It starts from birth so basically youre going through this forever and ever. Amen. Until you die.

Sickle cell disease causes red blood cells to become curved and rigid, leading to severe pain.

Hell on wheels, explained DAguilar. The most excruciating pains you could think about. Something I wouldnt wish on my worst enemy.

Anemia is another common complication and often requires multiple blood transfusions. Thats where George Murphy, PhD, a stem cell scientist at the Center for Regenerative Medicine at Boston Medical Center, enters the picture.

Dr. George Murphy, stem cell scientist, explains the brewing blood process. (WBZ-TV)

We like to actually work on diseases that directly impact this under-served community, one of which is sickle cell disease, said Murphy.

He and his team are working on growing personalized blood cells in the lab that could one day help patients like DAguilar.

In essence, sort of brew blood, said Murphy.

Blood being brewed in lab. (WBZ-TV)

Using a small sample of a patients own blood, scientists can reprogram red blood cells back into master stem cells and then coax them back into red blood cells that are unique to that patient. They can then grow the red blood cells over and over again in the lab.

We could actually make a stem cell line from those particular patients who suffer from sickle cell disease, says Murphy.

Such personalized blood could meet a patients transfusion demands and even reduce the effects of the disease. DAguilar said that would be a win.

Scientist rotates brewed blood in sac. (WBZ-TV)

Not only for me but other people suffering, he said. That would be a godsend.

The process could assist millions of people worldwide who need blood products.

You could actually make a universal supply of blood that could be transfused into anyone, says Murphy.

Although not ready for prime time yet, stem cell derived blood could be available for transfusions in the general population, as Murphy says, Sooner than you think.

Follow Dr. Mallika Marshall on Twitter Mallika Marshall, MD, is an Emmy-award winning journalist and physician who serves as the regular Health Reporter at WBZ-TV in Boston. A practicing physician who is Board Certified in both internal medicine a...

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Local Doctor Working To 'Brew Blood' To Combat Certain Disorders - CBS Boston / WBZ

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